King's College London

Research portal

Dr Ashley Jones

  1. Meta-analysis of pharmacogenetic interactions in amyotrophic lateral sclerosis clinical trials

    van Eijk, R. P. A. , Jones, A. , Sproviero, W. , Shatunov, A. , Shaw, P. J. , Leigh, P. N. , Young, C. A. , Shaw, C. E. , Mora, G. , Mandrioli, J. , Borghero, G. , Volanti, P. , Diekstra, F. P. , van Rheenen, W. , Verstraete, E. , Eijkemans, M. J. C. , Veldink, J. H. , Chio, A. , Al-Chalabi, A. , van den Berg, L. H. & 2 others van Es, M. A. & For UKMND-LiCALS and LITALS Study Group 31 Oct 2017 In : Neurology. 89, 18, p. 1915-1922 8 p.

    Research output: Contribution to journalArticle

  2. A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK

    Morgan, S., Shatunov, A., Sproviero, W., Jones, A. R., Shoai, M., Hughes, D., Al Khleifat, A., Malaspina, A., Morrison, K. E., Shaw, P. J., Shaw, C. E., Sidle, K., Orrell, R. W., Fratta, P., Hardy, J., Pittman, A. & Al-Chalabi, A. 1 Jun 2017 In : Brain : a journal of neurology. 140, 6, p. 1611-1618 8 p.

    Research output: Contribution to journalArticle

  3. ATXN2 trinucleotide repeat length correlates with risk of ALS

    Sproviero, W. , Shatunov, A. , Stahl, D. , Shoai, M. , van Rheenen, W. , Jones, A. R. , Al-Sarraj, S. , Andersen, P. M. , Bonini, N. M. , Conforti, F. L. , Van Damme, P. , Daoud, H. , Del Mar Amador, M. , Fogh, I. , Forzan, M. , Gaastra, B. , Gellera, C. , Gitler, A. D. , Hardy, J. , Fratta, P. & 27 others La Bella, V., Le Ber, I., Van Langenhove, T., Lattante, S., Lee, Y. C., Malaspina, A., Meininger, V., Millecamps, S., Orrell, R., Rademakers, R., Robberecht, W., Rouleau, G., Ross, O. A., Salachas, F., Sidle, K., Smith, B. N., Soong, B. W., Sorarù, G., Stevanin, G., Kabashi, E., Troakes, C., van Broeckhoven, C., Veldink, J. H., van den Berg, L. H., Shaw, C. E., Powell, J. F. & Al-Chalabi, A. 24 Nov 2016 In : Neurobiology of Aging.

    Research output: Contribution to journalArticle

  4. C9orf72 expansion differentially affects males with spinal onset amyotrophic lateral sclerosis

    Rooney, J., Fogh, I., Westeneng, H-J., Vajda, A., McLaughlin, R., Heverin, M., Jones, A., van Eijk, R., Calvo, A., Mazzini, L., Shaw, C., Morrison, K., Shaw, P. J., Robberecht, W., Van Damme, P., Al-Chalabi, A., van den Berg, L., Chiò, A., Veldink, J. & Hardiman, O. 23 Sep 2016 In : Journal of neurology, neurosurgery, and psychiatry. 7 p.

    Research output: Contribution to journalArticle

  5. NEK1 variants confer susceptibility to amyotrophic lateral sclerosis

    Kenna, K. P. , van Doormaal, P. T. C. , Dekker, A. M. , Ticozzi, N. , Kenna, B. J. , Diekstra, F. P. , van Rheenen, W. , van Eijk, K. R. , Jones, A. R. , Keagle, P. , Shatunov, A. , Sproviero, W. , Smith, B. N. , van Es, M. A. , Topp, S. D. , Kenna, A. , Miller, J. W. , Fallini, C. , Tiloca, C. , McLaughlin, R. L. & 62 others Vance, C., Troakes, C., Colombrita, C., Mora, G., Calvo, A., Verde, F., Al-Sarraj, S., King, A., Calini, D., de Belleroche, J., Baas, F., van der Kooi, A. J., de Visser, M., Ten Asbroek, A. L. M. A., Sapp, P. C., McKenna-Yasek, D., Polak, M., Asress, S., Muñoz-Blanco, J. L., Strom, T. M., Meitinger, T., Morrison, K. E., Lauria, G., Williams, K. L., Leigh, P. N., Nicholson, G. A., Blair, I. P., Leblond, C. S., Dion, P. A., Rouleau, G. A., Pall, H., Shaw, P. J., Turner, M. R., Talbot, K., Taroni, F., Boylan, K. B., Van Blitterswijk, M., Rademakers, R., Esteban-Pérez, J., García-Redondo, A., Van Damme, P., Robberecht, W., Chio, A., Gellera, C., Drepper, C., Sendtner, M., Ratti, A., Glass, J. D., Mora, J. S., Basak, N. A., Hardiman, O., Ludolph, A. C., Andersen, P. M., Weishaupt, J. H., Brown, R. H., Al-Chalabi, A., Silani, V., Shaw, C. E., van den Berg, L. H., Veldink, J. H., Landers, J. E. & SLAGEN Consortium 1 Sep 2016 In : Nature Genetics. 48, 9, p. 1037-42 6 p.

    Research output: Contribution to journalLetter

  6. Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosis

    Gaastra, B., Shatunov, A., Pulit, S., Jones, A. R., Sproviero, W., Gillett, A., Chen, Z., Kirby, J., Fogh, I., Powell, J. F., Leigh, P. N., Morrison, K. E., Shaw, P. J., Shaw, C. E., van den Berg, L. H., Veldink, J. H., Lewis, C. M. & Al-Chalabi, A. 1 Sep 2016 In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration . p. 1-7 7 p.

    Research output: Contribution to journalArticle

  7. Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

    van Rheenen, W. , Shatunov, A. , Dekker, A. M. , McLaughlin, R. L. , Diekstra, F. P. , Pulit, S. L. , van der Spek, R. A. A. , Võsa, U. , de Jong, S. , Robinson, M. R. , Yang, J. , Fogh, I. , van Doormaal, P. T. , Tazelaar, G. H. P. , Koppers, M. , Blokhuis, A. M. , Sproviero, W. , Jones, A. R. , Kenna, K. P. , van Eijk, K. R. & 158 others Harschnitz, O., Schellevis, R. D., Brands, W. J., Medic, J., Menelaou, A., Vajda, A., Ticozzi, N., Lin, K., Rogelj, B., Vrabec, K., Ravnik-Glavač, M., Koritnik, B., Zidar, J., Leonardis, L., Grošelj, L. D., Millecamps, S., Salachas, F., Meininger, V., de Carvalho, M., Pinto, S., Mora, J. S., Rojas-García, R., Polak, M., Chandran, S., Colville, S., Swingler, R., Morrison, K. E., Shaw, P. J., Hardy, J., Orrell, R. W., Pittman, A., Sidle, K., Fratta, P., Malaspina, A., Topp, S., Petri, S., Abdulla, S., Drepper, C., Sendtner, M., Meyer, T., Ophoff, R. A., Staats, K. A., Wiedau-Pazos, M., Lomen-Hoerth, C., Van Deerlin, V. M., Trojanowski, J. Q., Elman, L., McCluskey, L., Basak, A. N., Tunca, C., Hamzeiy, H., Parman, Y., Meitinger, T., Lichtner, P., Radivojkov-Blagojevic, M., Andres, C. R., Maurel, C., Bensimon, G., Landwehrmeyer, B., Brice, A., Payan, C. A. M., Saker-Delye, S., Dürr, A., Wood, N. W., Tittmann, L., Lieb, W., Franke, A., Rietschel, M., Cichon, S., Nöthen, M. M., Amouyel, P., Tzourio, C., Dartigues, J-F., Uitterlinden, A. G., Rivadeneira, F., Estrada, K., Hofman, A., Curtis, C., Blauw, H. M., van der Kooi, A. J., de Visser, M., Goris, A., Weber, M., Shaw, C. E., Smith, B. N., Pansarasa, O., Cereda, C., Del Bo, R., Comi, G. P., D'Alfonso, S., Bertolin, C., Sorarù, G., Mazzini, L., Pensato, V., Gellera, C., Tiloca, C., Ratti, A., Calvo, A., Moglia, C., Brunetti, M., Arcuti, S., Capozzo, R., Zecca, C., Lunetta, C., Penco, S., Riva, N., Padovani, A., Filosto, M., Muller, B., Stuit, R. J., Blair, I., Zhang, K., McCann, E. P., Fifita, J. A., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Grosskreutz, J., Witte, O. W., Ringer, T., Prell, T., Stubendorff, B., Kurth, I., Hübner, C. A., Leigh, P. N., Casale, F., Chio, A., Beghi, E., Pupillo, E., Tortelli, R., Logroscino, G., Powell, J., Ludolph, A. C., Weishaupt, J. H., Robberecht, W., Van Damme, P., Franke, L., Pers, T. H., Brown, R. H., Glass, J. D., Landers, J. E., Hardiman, O., Andersen, P. M., Corcia, P., Vourc'h, P., Silani, V., Wray, N. R., Visscher, P. M., de Bakker, P. I. W., van Es, M. A., Pasterkamp, R. J., Lewis, C. M., Breen, G., Al-Chalabi, A., van den Berg, L. H., Veldink, J. H. & PARALS Registry 25 Jul 2016 In : Nature Genetics.

    Research output: Contribution to journalArticle

  8. Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

    Fogh, I. , Lin, K. , Tiloca, C. , Rooney, J. , Gellera, C. , Diekstra, F. P. , Ratti, A. , Shatunov, A. , Van Es, M. A. , Proitsi, P. , Jones, A. , Sproviero, W. , Chiò, A. , McLaughlin, R. L. , Sorarù, G. , Corrado, L. , Stahl, D. , Del Bo, R. , Cereda, C. , Castellotti, B. & 29 others Glass, J. D., Newhouse, S., Dobson, R., Smith, B. N., Topp, S., Van Rheenen, W., Meininger, V., Melki, J., Morrison, K. E., Shaw, P. J., Leigh, P. N., Andersen, P. M., Comi, G. P., Ticozzi, N., Mazzini, L., D'Alfonso, S., Traynor, B. J., Van Damme, P., Robberecht, W., Brown, R. H., Landers, J. E., Hardiman, O., Lewis, C. M., Van Den Berg, L. H., Shaw, C. E., Veldink, J. H., Silani, V., Al-Chalabi, A. & Powell, J. 1 Jul 2016 In : JAMA Neurology. 73, 7, p. 812-820 9 p.

    Research output: Contribution to journalArticle

  9. The ALSFRS as an outcome measure in therapeutic trials and its relationship to symptom onset

    Proudfoot, M., Jones, A., Talbot, K., Al-Chalabi, A. & Turner, M. R. 11 Feb 2016 In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration . p. 1-12 12 p.

    Research output: Contribution to journalArticle

  10. Regionality of disease progression predicts prognosis in amyotrophic lateral sclerosis

    Van Der Kleij, L. A., Jones, A. R., Steen, I. N., Young, C. A., Shaw, P. J., Shaw, C. E., Leigh, P. N., Turner, M. R. & Al-Chalabi, A. 27 Nov 2015 In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration . 16, 7-8, p. 442-447 6 p.

    Research output: Contribution to journalArticle

  11. Investigation of next-generation sequencing technologies as a diagnostic tool for amyotrophic lateral sclerosis

    Morgan, S., Shoai, M., Fratta, P., Sidle, K., Orrell, R., Sweeney, M. G., Shatunov, A., Sproviero, W., Jones, A., Al-Chalabi, A., Malaspina, A., Houlden, H., Hardy, J. & Pittman, A. Mar 2015 In : Neurobiology of Aging. 36, 3, p. 1600.e5-1600.e8 3 p.

    Research output: Contribution to journalArticle

  12. Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes

    Jones, A. R., Troakes, C., King, A., Sahni, V., De Jong, S., Bossers, K., Papouli, E., Mirza, M., Al-Sarraj, S., Shaw, C. E., Shaw, P. J., Kirby, J., Veldink, J. H., Macklis, J. D., Powell, J. F. & Al-Chalabi, A. 19 Feb 2015 In : Neurobiology of Aging. p. 2006.e1-2006.e9 9 p.

    Research output: Contribution to journalArticle

  13. Intermediate length C9orf72 expansion in an ALS patient without classical C9orf72 neuropathology

    Beer, A. M., Cooper-Knock, J., Higginbottom, A., Highley, J. R., Wharton, S. B., Ince, P. G., Milano, A., Jones, A. A., Al-Chalabi, A., Kirby, J. & Shaw, P. J. 2014 In : Amyotrophic lateral sclerosis & frontotemporal degeneration. p. 1-3 3 p.

    Research output: Contribution to journalArticle

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