Research output per year
Research output per year
Personal profile
Research interests
Overview
Research is focused on the development and biopharmaceutical application of respiratory and intestinal epithelial cell culture models. Drug permeability, metabolism and gene delivery are studied:
- enhancement of drug transport
- presystemic drug metabolism
- epithelial pathology / toxicity
Inhaled Drug Delivery
“Inhalation biopharmaceutics” encompasses anything that may affect the rate or extent of drug absorption from the lung. Research projects in this emerging field include:
- Dissolution in lung fluid
- Mucociliary and macrophage interactions
- Drug metabolism
- Epithelial permeability
- Toxicity of delivery vehicles (excipients, nanoparticles)
All these events occur at (or in) the respiratory epithelium.
Oral Drug Delivery
Current projects investigate interactions between intestinal fluid, the intestinal epithelium, orally administered drugs and formulation excipients.
Clinical Pharmaceutics
Projects with innovation aimed at improving practice in the manufacturing of pharmaceutical products.
Research interests (short)
Inhaled medicines; pulmonary biopharmaceutics; drug targeting to the lung.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Bacterial diversity, viability and stability in lyophilised faecal microbiota capsules support ongoing clinical use
Zain, N. M., Merrick, B., Martin-Lilley, T., Edwards, L. A., ter Linden, D., Tsoka, S., Mason, J., Hatton, G., Allen, E., Royall, P., Lilley, A., Bruce, K., Shawcross, D., Goldenberg, S. & Forbes, B., 10 Jun 2025, In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. 678, 125703.Research output: Contribution to journal › Article › peer-review
Open Access -
Brain distribution study of [14C]-Riluzole following intranasal administration in mice
Baker, R. S., Wang, J. T. W., Rouatbi, N., Lu, Y., Al-adhami, T., Asker, D., Rahman, K. M., Al-Chalabi, A., Forbes, B., Bansal, S. & Al-Jamal, K. T., 10 Feb 2025, In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. 670, 125195.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
Intratracheal Administration of Nanoplastics With Varying Surface Hydrophobicity Results in Coarsely Vacuolated Alveolar Macrophages, Transient Respiratory Inflammation, and Mild Collagen Deposition
Babin, A., Riffo Vasquez, Y., Bodhaniya, A., Jones, S., Forbes, B., Sunassee, K., T. M. de Rosales, R., Wright, S., Page, C. & Dailey, L. A., 14 Jan 2025, (Accepted/In press) In: Nano Select. e202400154.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeted nasal delivery of LNP-mRNAs aerosolised by Rayleigh breakup technology
Li, H.-Y., Paramanandana, A., Kim, S. Y., Granger, L., Raimi-Abraham, B. T., Shattock, R., Makatsoris, C. & Forbes, B., 15 Mar 2025, In: INTERNATIONAL JOURNAL OF PHARMACEUTICS. 672, p. 125335 125335.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
PPAR Gamma Receptor: A Novel Target to Improve Morbidity in Preterm Babies
Victor, S., Forbes, B., Greenough, A. & Edwards, D., 27 Oct 2023, In: Pharmaceuticals. 16, 11, p. 1530 11 p., 1530.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus)86 Downloads (Pure)
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Ondansetron: Ondansetron nasal spray for the treatment of pregnancy-related nausea and vomiting
Forbes, B. (Primary Investigator)
6/01/2025 → 5/01/2026
Project: Research
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Defining targets for intervention in the aetiopathogenic pathways of Parkinson’s and related diseases
Forbes, B. (Primary Investigator), Dobbs, J. (Co-Investigator) & Dobbs, S. (Co-Investigator)
1/01/2025 → 31/12/2027
Project: Research
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Host-Microbiome Interaction: Clinical Pharmacology & Therapeutics
Forbes, B. (Primary Investigator), Dobbs, J. (Co-Investigator) & Dobbs, S. (Co-Investigator)
1/07/2024 → 30/11/2027
Project: Research
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Does exenatide in conjunction with therapeutic hypothermia reduce cerebral palsy in neonatal hypoxic-ischemic encephalopathy?
Victor, S. (Primary Investigator), Forbes, B. (Co-Investigator) & Prevost, T. (Co-Investigator)
1/05/2023 → 31/12/2026
Project: Research
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Advanced experimental & computational methods for optimising nasal drug delivery
Forbes, B. (Primary Investigator) & Dreiss, C. (Co-Investigator)
1/10/2022 → 30/09/2026
Project: Research