Search results

• Active

  Nuclear to synaptic signalling dysregulation by Annexin A11 in ALS

  Smith, B. (Primary Investigator), Mitchell, J. (Co-Investigator), Mizielinska, S. (Co-Investigator), Ruepp, M.-D. (Co-Investigator), Troakes, C. (Co-Investigator) & Vance, C. (Co-Investigator)

  MNDA Motor Neurone Disease Association

  1/04/2025 → 31/03/2026

  Project: Research

• MNDSTaR (MND: MNDSTaR: The King's-LifeArc Solution for Motor Neurone Disease Target Validation

  Al Khleifat, A. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Iacoangeli, A. (Co-Investigator), Mitchell, J. (Co-Investigator) & Smith, B. (Co-Investigator)

  LifeArc

  1/05/2024 → 30/04/2026

  Project: Research

• Finished

  Alzheimer’s Research UK London Network Centre Grant Sub-project: Brad Smith

  Smith, B. (Primary Investigator)

  Alzheimer's Research UK

  1/04/2024 → 30/06/2024

  Project: Research

• Validating new promising drug targets in Amyotrophic Lateral Sclerosis

  Iacoangeli, A. (Primary Investigator), Al Khleifat, A. (Co-Investigator), Al-Chalabi, A. (Co-Investigator), Mitchell, J. (Co-Investigator), Smith, B. (Co-Investigator) & Sreedharan, J. (Co-Investigator)

  Alzheimer's Research UK

  1/01/2023 → 31/01/2025

  Project: Research

• Smith/Apr21/: Mapping neuropathological signatures of rare ALS genes: a means to identify key ALS functional pathways.

  Smith, B. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Troakes, C. (Co-Investigator) & Vance, C. (Co-Investigator)

  MNDA Motor Neurone Disease Association

  1/05/2022 → 31/03/2025

  Project: Research

• Identifying ALS associated molecular and cellular changes in an Annexin A11 mutant knock-in mouse model

  Smith, B. (Primary Investigator), Mitchell, J. (Co-Investigator) & Vance, C. (Co-Investigator)

  Frick Foundation Frick Foundation for ALS Research

  1/03/2021 → 31/08/2024

  Project: Research

• Elucidating the role of Calcyclin in the pathogenesis of ALS and Alzheimer's Disease

  Smith, B. (Primary Investigator), Adinolfi, S. (Co-Investigator), Houart, C. (Co-Investigator) & Shaw, C. (Co-Investigator)

  Motor Neurone Disease Association

  1/10/2017 → 31/07/2021

  Project: Research

• A Drosophila model for an Annexin gene causing ALS

  Fanto, M. (Primary Investigator), Shaw, C. (Co-Investigator) & Smith, B. (Co-Investigator)

  Motor Neurone Disease Association

  1/09/2017 → 31/12/2020

  Project: Research

  • Lipocortin 100%
  • Fruit Fly Model 100%

• Gene hunting in Middle-eastern adult onset ALS cases containing a high degree of consanguinity

  Smith, B. (Primary Investigator) & Shaw, C. (Co-Investigator)

  Motor Neurone Disease Association

  1/09/2016 → 31/08/2018

  Project: Research

• From ALS exomes to functional assays: turning candidates into confirmed genes

  Smith, B. (Primary Investigator), Houart, C. (Co-Investigator) & Shaw, C. (Co-Investigator)

  Medical Research Foundation

  1/07/2015 → 30/09/2018

  Project: Research

• Gene hunting in young onset amyotrophic lateral sclerosis patients

  Shaw, C. (Primary Investigator) & Smith, B. (Co-Investigator)

  1/10/2014 → 30/09/2015

  Project: Research

• Exome sequencing of young onset sporadic patients with amyotrophic lateral sclerosis

  Shaw, C. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Smith, B. (Co-Investigator) & Topp, S. (Co-Investigator)

  1/10/2014 → 30/09/2016

  Project: Research