Carmine Pariante

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  The effects of repeated inflammatory insults on programming and function of hippocampal progenitor cells: a study towards understanding consequences of early life immune challenges for neuropsychiatric disorders

  Zunszain, P. (Primary Investigator), Pariante, C. (Co-Investigator) & Salam, A. (Co-Investigator)

  Francis Crick Institute

  1/09/2015 → 31/08/2016

  Project: Research

• NIHR Senior Investigator Award

  Pariante, C. (Primary Investigator)

  1/09/2015 → 31/08/2020

  Project: Research

• An evidence synthesis approach to evaluating the mechanisms of depression, pregnancies, Chlamydia infection and behaviour in early adulthood

  Koukounari, A. (Primary Investigator), Maughan, B. (Co-Investigator), Pariante, C. (Co-Investigator), Pickles, A. (Co-Investigator) & Rahman, Q. (Co-Investigator)

  1/09/2015 → 31/08/2020

  Project: Research

• Enhancing antidepressant efficacy acting upon metabolic and inflammatory factors modulated by lifestyle - ENHANCE

  Pariante, C. (Primary Investigator)

  1/06/2015 → 31/05/2016

  Project: Research

• Neurocognitive basis and treatment of self-blaming bias and recurrence risk in depressive disorders

  Zahn, R. (Primary Investigator), Barker, G. (Co-Investigator), Cleare, A. (Co-Investigator), Giampietro, V. (Co-Investigator), Koukounari, A. (Co-Investigator), Pariante, C. (Co-Investigator), Tylee, A. (Co-Investigator), Williams, S. (Co-Investigator) & Young, A. (Co-Investigator)

  1/05/2015 → 30/04/2020

  Project: Research

• Improving depression treatment: from blood samples to brain insights

  Zunszain, P. (Primary Investigator), Mehta, M. (Co-Investigator), Pariante, C. (Co-Investigator), Price, J. (Co-Investigator), Stone, J. (Co-Investigator), Thuret, S. (Co-Investigator) & Vernon, A. (Co-Investigator)

  1/05/2015 → 30/04/2016

  Project: Research

• Neurocognitive basis and treatment of self-blaming bias and recurrence risk in depressive disorders

  Zahn, R. (Primary Investigator), Barker, G. (Co-Investigator), Cleare, A. (Co-Investigator), Giampietro, V. (Co-Investigator), Koukounari, A. (Co-Investigator), Pariante, C. (Co-Investigator), Shearer, J. (Co-Investigator), Tylee, A. (Co-Investigator), Williams, S. (Co-Investigator) & Young, A. (Co-Investigator)

  1/05/2015 → 30/04/2020

  Project: Research

• Improving depression treatment: inflammatory and kynurenine pathways as mechanistic targets of ketamine action

  Zunszain, P. (Primary Investigator), Pariante, C. (Co-Investigator), Price, J. (Co-Investigator), Srivastava, D. (Co-Investigator), Stone, J. (Co-Investigator) & Young, A. (Co-Investigator)

  1/04/2015 → 30/09/2016

  Project: Research

• Understanding the molecular basis for the use of adjunctive anti-inflammatory treatment in treatment resistant depression: a stratified, randomised, placebo-controlled, experimental medicine study using Minocycline

  Mondelli, V. (Primary Investigator), Pariante, C. (Co-Investigator) & Young, A. (Co-Investigator)

  1/04/2015 → 30/09/2016

  Project: Research

• A study to deliver Stage 1 of a new three-stages pipeline for antidepressant targets identification, prioritisation and validation

  Pariante, C. (Primary Investigator), Mondelli, V. (Co-Investigator), Young, A. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/04/2015 → 30/09/2016

  Project: Research

• An evidence synthesis approach to evaluating the interaction of adverse sexual health outcomes with mental illness and impulses in early adulthood

  Koukounari, A. (Primary Investigator), Maughan, B. (Co-Investigator), Pariante, C. (Co-Investigator), Pickles, A. (Co-Investigator) & Rahman, Q. (Co-Investigator)

  1/04/2015 → 31/03/2020

  Project: Research

• Neuroimaging scopolamine and ketamine antidepressant response

  Stone, J. (Primary Investigator), Mehta, M. (Co-Investigator), Pariante, C. (Co-Investigator), Zelaya, F. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/03/2015 → 28/02/2020

  Project: Research

• TARGETING BRAIN INFLAMMATION IN DEPRESSION USING MINOCYCLINE: A STRATIFIED, RANDOMISED, PLACEBO-CONTROLLED, EXPERIMENTAL MEDICINE STUDY, INTEGRATING BEHAVIOUR, PET, MRI AND PERIPHERAL BIOMARKERS

  Pariante, C. (Primary Investigator), Barker, G. (Co-Investigator), Cash, D. (Co-Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Egeland, M. (Co-Investigator), Mondelli, V. (Co-Investigator), Turkheimer, F. (Co-Investigator), Tylee, A. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/03/2015 → 29/02/2020

  Project: Research

• T-FLAME: Dissecting neuroinflammation in trauma - integrating behaviour, PET, MRI biomarkers and molecular mechanisms in humans and animal models

  Pariante, C. (Primary Investigator), Barker, G. (Co-Investigator) & Cash, D. (Co-Investigator)

  1/03/2015 → 28/02/2018

  Project: Research

• Mechanisms underlying suicide: molecular and neuroimaging signatures of drug that modulate risk

  Zunszain, P. (Primary Investigator), Cash, D. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/03/2015 → 28/02/2016

  Project: Research

• WATERFLAME

  Turkheimer, F. (Primary Investigator), Dazzan, P. (Co-Investigator), Pariante, C. (Co-Investigator) & Vernon, A. (Co-Investigator)

  1/03/2015 → 28/02/2020

  Project: Research

• Defining the disturbance in cortical glutamate and GABA function in psychosis, its origins and consequences

  Zunszain, P. (Primary Investigator) & Pariante, C. (Co-Investigator)

  MRC Medical Research Council

  1/02/2015 → 30/09/2017

  Project: Research

• Fast-acting antidepressants: understanding ketamine to find new pharmacological targets

  Zunszain, P. (Primary Investigator), Pariante, C. (Co-Investigator) & Price, J. (Co-Investigator)

  1/02/2015 → 31/01/2017

  Project: Research

• Consortium for Neuroimmunology of Mood Disorders and Alzheimer's disease

  Pariante, C. (Primary Investigator), Turkheimer, F. (Primary Investigator), Barker, G. (Co-Investigator), Cash, D. (Co-Investigator), Cleare, A. (Co-Investigator), Dell' Acqua, F. (Co-Investigator), Mondelli, V. (Co-Investigator), So, P.-W. (Co-Investigator), Vernon, A. (Co-Investigator), Williams, S. (Co-Investigator), Young, A. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  Wellcome Trust

  1/01/2015 → 30/06/2024

  Project: Research

• Using stress-related biomarkers to predict clinical outcomes in first episode psychosis

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Murray, R. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/11/2014 → 31/10/2016

  Project: Research

• Biological, social and clinical predictors of suicidal behaviour in first episode psychosis

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Murray, R. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/11/2014 → 31/10/2016

  Project: Research

• Developing a biomarkets-based tool to predict treatment response in first-episode psychosis

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/10/2014 → 30/09/2017

  Project: Research

• The role of neurogenesis in post-partum depression: a new target for prediction and intervention

  Thuret, S. (Primary Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/10/2014 → 30/09/2016

  Project: Research

• Consortium for Neuroimmunology of Mood disorders & Alzheimer's disease

  Pariante, C. (Primary Investigator), Barker, G. (Co-Investigator), Cash, D. (Co-Investigator), Dell' Acqua, F. (Co-Investigator), Mondelli, V. (Co-Investigator), So, P.-W. (Co-Investigator), Turkheimer, F. (Co-Investigator), Tylee, A. (Co-Investigator), Vernon, A. (Co-Investigator), Williams, S. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/10/2014 → 30/09/2019

  Project: Research

• Mechanisms underlying suicide: defining molecular signatures of drugs that modulate risk

  Zunszain, P. (Primary Investigator), Cattaneo, A. (Co-Investigator), Egeland, M. (Co-Investigator), Fernandes, C. (Co-Investigator), Pariante, C. (Co-Investigator), So, P.-W. (Co-Investigator) & Thuret, S. (Co-Investigator)

  1/10/2014 → 30/09/2016

  Project: Research

• Development of New Intervention for Families Experiencing Domestic Abuse

  Pawlby, S. (Primary Investigator) & Pariante, C. (Co-Investigator)

  1/10/2014 → 30/09/2015

  Project: Research

• Immuno-psychiatry: a consortium to test the opportunity for immunotherapeutics in psychiatry

  Pariante, C. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dobson, R. (Co-Investigator), Newhouse, S. (Co-Investigator), Stewart, R. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  MRC Medical Research Council

  1/10/2014 → 30/09/2016

  Project: Research

• Inflamation and Trauma Across the Life Span

  Pariante, C. (Primary Investigator), Conroy, S. (Co-Investigator), Hatch, S. (Co-Investigator), Hotopf, M. (Co-Investigator), Pawlby, S. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/08/2014 → 1/08/2015

  Project: Research

• Neurobiological abnormalities in congenital adrenal hyperplasia (CAH): finding the molecular signature in vitro and in vivo

  Pariante, C. (Primary Investigator), Cattaneo, A. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/06/2014 → 31/05/2016

  Project: Research

• NIHR Senior Investigator Award

  Pariante, C. (Primary Investigator)

  1/04/2014 → 31/03/2019

  Project: Research

• The Intergenerational Transmission of Childhood Maltreatment: Finding the Molecular Signature

  Pariante, C. (Primary Investigator)

  1/03/2014 → 28/02/2019

  Project: Research

• Identification of transcriptomic predicitive biomarkers of IFN-alpha induced depression and underlying mechanisms: focus on stress related pathways using a combined approach in HCV patients and in hippocampal progenitor stem cells.

  Cattaneo, A. (Primary Investigator), Hotopf, M. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  15/01/2014 → 14/01/2016

  Project: Research

• Antenatal depression and the epigenetics of developmental programming

  Pariante, C. (Primary Investigator) & Mill, J. (Co-Investigator)

  Brain and Behavior Research Foundation

  15/01/2014 → 14/01/2016

  Project: Research

• Depression n pregnancy and adverse obstetric neonatal outcomes

  Pariante, C. (Primary Investigator), Conroy, S. (Co-Investigator) & Pawlby, S. (Co-Investigator)

  1/01/2014 → 31/12/2015

  Project: Research

• Identifying novel and fast treatment targets for depression: learning from the molecular actions of ketamine in a human neuronal model

  Zunszain, P. (Primary Investigator), Cattaneo, A. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/01/2014 → 31/12/2016

  Project: Research

• Inflammation and Psychosis : translating research findings into clincal practice

  Mondelli, V. (Primary Investigator), Bhattacharyya, S. (Co-Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Howes, O. (Co-Investigator), McGuire, P. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/01/2014 → 31/12/2017

  Project: Research

• Inflammation and psychosis : translating research findings into clinical practise

  Mondelli, V. (Primary Investigator), Bhattacharyya, S. (Co-Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Howes, O. (Co-Investigator), McGuire, P. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/12/2013 → 30/11/2018

  Project: Research

• Inflammation and psychosis: translating findings on biological mechanisms into clinical practice

  Mondelli, V. (Primary Investigator), Cattaneo, A. (Co-Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/11/2013 → 30/10/2016

  Project: Research

• NEUROBIOLOGICAL ABNORMALITIES IN CONGENITAL ADRENAL HYPERPLASIA (CAH): FINDING THE MOLECULAR SIGNATURE IN VITRO

  Pariante, C. (Primary Investigator), Cattaneo, A. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  1/11/2013 → 30/04/2015

  Project: Research

• Neuroinflammation in psychosis : a proof-of-concept mechanistic study of changes in myelin content and microglia activation using the anti-inflammatory , Minocycline

  Giordano, A. (Primary Investigator), Dazzan, P. (Co-Investigator), Howes, O. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Neuroinflammation in psychosis : a proof-of-concept mechanistic study of changes in myelin content and microglia activation using the anti-inflammatory, Minocycline

  Giordano, A. (Primary Investigator), Dazzan, P. (Co-Investigator), Howes, O. (Co-Investigator), Pariante, C. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Williams, S. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Identification of inflammation pathways involved in the predisposition to decreased neurogenesis and depression

  Egeland, M. (Primary Investigator), Fernandes, C. (Co-Investigator), Pariante, C. (Co-Investigator), Thuret, S. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  Lundbeck Foundation

  1/10/2013 → 30/09/2015

  Project: Research

• Dissecting brain inflammation in depression : Integrating behaviour,PET,MRS,MRI,cytokines and transcriptomics

  Pariante, C. (Primary Investigator), Barker, G. (Co-Investigator), Cleare, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Dobson, R. (Co-Investigator), Hayday, A. (Co-Investigator), Hotopf, M. (Co-Investigator), Howes, O. (Co-Investigator), Kapur, S. (Co-Investigator), Pickles, A. (Co-Investigator), Rabiner, E. (Co-Investigator), Taylor, M. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Tylee, A. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Effectiveness and cost-effectiveness of perinatal mental health services

  Bick, D. (Primary Investigator), Howard, L. (Primary Investigator), Byford, S. (Co-Investigator), Hunter, M. (Co-Investigator), Morgan, C. (Co-Investigator), Pariante, C. (Co-Investigator), Pawlby, S. (Co-Investigator), Pickles, A. (Co-Investigator) & Rose, D. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2013 → 30/09/2019

  Project: Research

• The neurobiological basis of Puerperal Psychosis : how multiple systems interact with brain vulnerability.

  Dazzan, P. (Primary Investigator), Clement, S. (Co-Investigator), Craig, M. (Co-Investigator), Howard, L. (Co-Investigator), Mehta, M. (Co-Investigator), Pariante, C. (Co-Investigator), Pickles, A. (Co-Investigator), Price, J. (Co-Investigator), Srivastava, D. (Co-Investigator) & Williams, S. (Co-Investigator)

  Medical Research Foundation

  1/09/2013 → 31/01/2017

  Project: Research

• Effectiveness and cost-effectiveness of perinatal mental health services (ESMI)

  Howard, L. (Primary Investigator), Bick, D. (Co-Investigator), Byford, S. (Co-Investigator), Hunter, M. (Co-Investigator), Morgan, C. (Co-Investigator), Pariante, C. (Co-Investigator), Pawlby, S. (Co-Investigator), Pickles, A. (Co-Investigator) & Rose, D. (Co-Investigator)

  DHSC Department of Health and Social Care

  1/09/2013 → 31/08/2018

  Project: Research

• In search of the right medication for psychosis

  Mondelli, V. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/09/2013 → 1/09/2014

  Project: Research

• Identifying molecular predictors of treatment response in first-episode psychosis

  Mondelli, V. (Primary Investigator), Dazzan, P. (Co-Investigator), McGuire, P. (Co-Investigator) & Pariante, C. (Co-Investigator)

  1/08/2013 → 1/08/2015

  Project: Research

• Depression in pregnancy and adverse obstetric and neonatal outcomes

  Conroy, S. (Primary Investigator), Pariante, C. (Co-Investigator) & Pawlby, S. (Co-Investigator)

  1/08/2013 → 1/07/2016

  Project: Research

• South East London Community Health Study (SELCoH) Phase 3

  Hotopf, M. (Primary Investigator), Breen, G. (Co-Investigator), Cleare, A. (Co-Investigator), Frissa, S. (Co-Investigator), Goodwin, L. (Co-Investigator), Hatch, S. (Co-Investigator), Pariante, C. (Co-Investigator) & Zunszain, P. (Co-Investigator)

  Maudsley Charity

  1/07/2013 → 30/09/2014

  Project: Research