Caroline Le Roy

2023

Interplay between the (Poly)phenol Metabolome, Gut Microbiome, and Cardiovascular Health in Women: A Cross-Sectional Study from the TwinsUK Cohort

Li, Y., Xu, Y., Le Roy, C., Hu, J., Steves, C. J., Bell, J. T., Spector, T. D., Gibson, R., Menni, C. & Rodriguez-Mateos, A., 14 Apr 2023, In: Nutrients. 15, 8, 1900.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Citations (Scopus)

2022

Characterisation, procedures and heritability of acute dietary intake in the Twins UK cohort: an observational study

Leeming, E. R., Mompeo, O., Turk, P., Bowyer, R. C. E., Louca, P., Johnson, A. J., Spector, T. D., Le Roy, C. & Gibson, R., 27 Feb 2022, (E-pub ahead of print) In: Nutrition Journal. 21, 1, 13.

Research output: Contribution to journal › Article › peer-review

Open Access

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3 Citations (Scopus)

175 Downloads (Pure)

Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome

Le Roy, C. I., Kurilshikov, A., Leeming, E. R., Visconti, A., Bowyer, R. C. E., Menni, C., Falchi, M., Koutnikova, H., Veiga, P., Zhernakova, A., Derrien, M. & Spector, T. D., Dec 2022, In: BMC Microbiology. 22, 1, p. 39 1 p., 39.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Citations (Scopus)

2021

Epigenome-wide association study of diet quality in the Women's Health Initiative and TwinsUK cohort

Do, W. L., Whitsel, E. A., Costeira, R., Masachs, O. M., Le Roy, C. I., Bell, J. T., Staimez, L. R., Stein, A. D., Smith, A. K., Horvath, S., Assimes, T. L., Liu, S., Manson, J. A. E., Shadyab, A. H., Li, Y., Hou, L., Bhatti, P., Jordahl, K., Narayan, K. M. V. & Conneely, K. N., 17 May 2021, In: International Journal of Epidemiology. 50, 2, p. 675-684 10 p.

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Large-scale association analyses identify host factors influencing human gut microbiome composition

Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J. Y., Kim, H. N., Lüll, K. & Barkan, E. & 84 others, Shah, S. A., Fornage, M., Szopinska-Tokov, J., Wallen, Z. D., Borisevich, D., Agreus, L., Andreasson, A., Bang, C., Bedrani, L., Bell, J. T., Bisgaard, H., Boehnke, M., Boomsma, D. I., Burk, R. D., Claringbould, A., Croitoru, K., Davies, G. E., van Duijn, C. M., Duijts, L., Falony, G., Fu, J., van der Graaf, A., Hansen, T., Homuth, G., Hughes, D. A., Ijzerman, R. G., Jackson, M. A., Jaddoe, V. W. V., Joossens, M., Jørgensen, T., Keszthelyi, D., Knight, R., Laakso, M., Laudes, M., Launer, L. J., Lieb, W., Lusis, A. J., Masclee, A. A. M., Moll, H. A., Mujagic, Z., Qibin, Q., Rothschild, D., Shin, H., Sørensen, S. J., Steves, C. J., Thorsen, J., Timpson, N. J., Tito, R. Y., Vieira-Silva, S., Völker, U., Völzke, H., Võsa, U., Wade, K. H., Walter, S., Watanabe, K., Weiss, S., Weiss, F. U., Weissbrod, O., Westra, H. J., Willemsen, G., Payami, H., Jonkers, D. M. A. E., Arias Vasquez, A., de Geus, E. J. C., Meyer, K. A., Stokholm, J., Segal, E., Org, E., Wijmenga, C., Kim, H. L., Kaplan, R. C., Spector, T. D., Uitterlinden, A. G., Rivadeneira, F., Franke, A., Lerch, M. M., Franke, L., Sanna, S., D’Amato, M., Pedersen, O., Paterson, A. D., Kraaij, R., Raes, J. & Zhernakova, A., Feb 2021, In: Nature Genetics. 53, 2, p. 156-165 10 p.

Research output: Contribution to journal › Article › peer-review

1032 Citations (Scopus)

Self-Reported Symptoms of COVID-19, Including Symptoms Most Predictive of SARS-CoV-2 Infection, Are Heritable

Williams, F. M. K., Freidin, M. B., Mangino, M., Couvreur, S., Visconti, A., Bowyer, R. C. E., Le Roy, C. I., Falchi, M., Mompeó, O., Sudre, C., Davies, R., Hammond, C., Menni, C., Steves, C. J. & Spector, T. D., 9 Feb 2021, (E-pub ahead of print) In: TWIN RESEARCH AND HUMAN GENETICS. 23, 6, p. 316-321 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Citations (Scopus)

The complexities of the diet-microbiome relationship: advances and perspectives

Leeming, E., Louca, B., Gibson, R., Menni, C., Spector, T. & Le Roy, C., 20 Jan 2021, In: Genome medicine. 13, 1, p. 10 10.

Research output: Contribution to journal › Review article › peer-review

Open Access

75 Citations (Scopus)

2020

A reference map of potential determinants for the human serum metabolome

IMI DIRECT consortium, 3 Dec 2020, In: Nature. 588, 7836, p. 135-140 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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276 Citations (Scopus)

205 Downloads (Pure)

Arrhythmic Gut Microbiome Signatures Predict Risk of Type 2 Diabetes

Reitmeier, S., Kiessling, S., Clavel, T., List, M., Almeida, E. L., Ghosh, T. S., Neuhaus, K., Grallert, H., Linseisen, J., Skurk, T., Brandl, B., Breuninger, T. A., Troll, M., Rathmann, W., Linkohr, B., Hauner, H., Laudes, M., Franke, A., Le Roy, C. I. & Bell, J. T. & 5 others, Spector, T., Baumbach, J., O'Toole, P. W., Peters, A. & Haller, D., 12 Aug 2020, In: Cell Host and Microbe. 28, 2, p. 258-272.e6

Research output: Contribution to journal › Article › peer-review

179 Citations (Scopus)

Associations between UK tap water and gut microbiota composition suggest the gut microbiome as a potential mediator of health differences linked to water quality

Bowyer, R. C. E., Schillereff, D. N., Jackson, M., Le Roy, C. I., Wells, P. M., Spector, T. D. & Steves, C. J., 23 May 2020, (Accepted/In press) In: Science of the Total Environment.

Research output: Contribution to journal › Article › peer-review

Consumption of Stilbenes and Flavonoids is Linked to Reduced Risk of Obesity Independently of Fiber Intake

Mompeo, O., Spector, T. D., Matey Hernandez, M., Le Roy, C., Istas, G., Le Sayec, M., Mangino, M., Jennings, A., Rodriguez-Mateos, A., Valdes, A. M. & Menni, C., 23 Jun 2020, In: Nutrients. 12, 6, p. 1-12 12 p., 1871.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Citations (Scopus)

Red Wine Consumption Associated With Increased Gut Microbiota α-Diversity in 3 Independent Cohorts

Le Roy, C. I., Wells, P. M., Si, J., Raes, J., Bell, J. T. & Spector, T. D., Jan 2020, In: Gastroenterology. 158, 1, p. 270-272.e2

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes

Menni, C., Zhu, J., Le Roy, C. I., Mompeo, O., Young, K., Rebholz, C. M., Selvin, E., North, K. E., Mohney, R. P., Bell, J. T., Boerwinkle, E., Spector, T. D., Mangino, M., Yu, B. & Valdes, A. M., 1 Nov 2020, In: Gut Microbes. 11, 6, p. 1632-1642 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access