Research output per year
Research output per year
Personal profile
Research interests
My research focus is the development and application of statistical methods in human genetics, to identify and characterise genes contributing to common, complex disorders. Current research includes genome-wide association studies and disease risk prediction using genetic and environmental factors.
Research interests (short)
Statistical methods for gene identification and characterisation in complex genetic disorders.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Antidepressant switching as a proxy phenotype for drug non-response: investigating clinical, demographic and genetic characteristics
Lo, C. W. H., Gillett, A. C., Iveson, M. H., Kamp, M., Fabbri, C., Wong, W. L. E., Handley, D., Pain, O., Vassos, E., Wray, N. R., Whalley, H. C., Li, D., Young, A. H., McIntosh, A. M., AMBER Research Team & Lewis, C. M., 2025.Research output: Working paper/Preprint › Preprint
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Depression symptom-specific genetic associations in clinically diagnosed and proxy case Alzheimer’s disease
Gilchrist, L., Spargo, T. P., Green, R. E., Coleman, J. R. I., Howard, D. M., Thorp, J. G., Adey, B. N., Lord, J., Davies, H. L., Mundy, J., ter Kuile, A. R., Davies, M. R., Hübel, C., Bristow, S., Lee, S. H., Rogers, H., Curtis, C., Kakar, S., Malouf, C. M. & Kalsi, G. & 14 others, , Feb 2025, In: Nature Mental Health . 3, 2, p. 212-228 17 p., 160.Research output: Contribution to journal › Article › peer-review
Open Access -
Genome-wide association study identifies common variants associated with breast cancer in South African Black women
Hayat, M., Chen, W. C., Babb de Villiers, C., Lee, S., Curtis, C., Newton, R., Waterboer, T., Sitas, F., Bradshaw, D., Muchengeti, M., Singh, E., Lewis, C., Ramsay, M., Mathew, C. G. & Brandenburg, J.-T., 14 Apr 2025, (E-pub ahead of print) In: Nature Communications. 16, 1, 11 p., 3542.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Investigating the genetic relationship between depression symptoms and Alzheimer’s Disease in clinically diagnosed and proxy cases
Gilchrist, L., Coleman, J., Howard, D., Adey, B., Davies, H. L., Mundy, J., ter Kuile, A., Davies, M., Bristow, S., Lee, S., Rogers, H., Curtis, C., Kalsi, G., Arathimos, R., Eley, T., Breen, G., Iacoangeli, A., Lewis, C. & Proitsi, P., 15 Jan 2025, In: Nature Mental Health .Research output: Contribution to journal › Article › peer-review
Open AccessFile64 Downloads (Pure) -
Recommendations for defining treatment outcomes in major psychiatric disorders using real-world data
Koch, E. & Lewis, C., 20 Feb 2025, (Accepted/In press) In: The Lancet Psychiatry.Research output: Contribution to journal › Review article › peer-review
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Accelerated biological aging: linking psychiatric disorders to age-related diseases and premature mortality
Mutz, J. (Primary Investigator) & Lewis, C. (Co-Investigator)
Brain and Behavior Research Foundation
15/01/2025 → 14/01/2027
Project: Research
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Understanding the causal mechanisms of antidepressant exposure and response
Lewis, C. (Primary Investigator)
1/08/2023 → 31/07/2028
Project: Research
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Longitudinal and genetic evaluation of type 2 diabetes and major depression
Lewis, C. (Primary Investigator)
1/04/2023 → 31/03/2026
Project: Research
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Maudsley BRC: NIHR SLaM BRC
Hotopf, M. (Primary Investigator), Brose, L. (Co-Investigator), Brown, J. (Co-Investigator), Chalder, T. (Co-Investigator), Cleare, A. (Co-Investigator), Coleman, J. (Co-Investigator), Cunningham, J. (Co-Investigator), Dazzan, P. (Co-Investigator), Deluca, P. (Co-Investigator), Desrivieres, S. (Co-Investigator), Di Forti, M. (Co-Investigator), Dobson, R. (Co-Investigator), Drummond, C. (Co-Investigator), Dutta, R. (Co-Investigator), Egerton, A. (Co-Investigator), Emsley, R. (Co-Investigator), Gilchrist, G. (Co-Investigator), Gillett, A. (Co-Investigator), Goadsby, P. (Co-Investigator), Happe, F. (Co-Investigator), Hirsch, C. (Co-Investigator), Hoffmann, J. (Co-Investigator), Ismail, K. (Co-Investigator), Koutsouleris, N. (Co-Investigator), Lewis, C. (Co-Investigator), Marsden, J. (Co-Investigator), McAlonan, G. (Co-Investigator), McNeill, A. (Co-Investigator), Mehta, M. (Co-Investigator), Mondelli, V. (Co-Investigator), Moran, R. (Co-Investigator), Moss-Morris, R. (Co-Investigator), Neale, J. (Co-Investigator), Pariante, C. (Co-Investigator), Pile, V. (Co-Investigator), Powell, T. (Co-Investigator), Robson, D. (Co-Investigator), Rucker, J. (Co-Investigator), Schmidt, U. (Co-Investigator), Sonuga-Barke, E. (Co-Investigator), Stahl, D. (Co-Investigator), Stewart, R. (Co-Investigator), Strang, J. (Co-Investigator), Sweeney, A. (Co-Investigator), Turkheimer, F. (Co-Investigator), Vassos, E. (Co-Investigator), Wong, C. (Co-Investigator), Wykes, T. (Co-Investigator), Young, A. (Co-Investigator), Zahn, R. (Co-Investigator) & Zelaya, F. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/12/2022 → 30/11/2027
Project: Research
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Integrating polygenic risk scores with clinical drug development
Lewis, C. (Primary Investigator) & Coleman, J. (Co-Investigator)
1/10/2022 → 30/09/2026
Project: Research
Activities
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Wellcome Trust Genetics, Genomics and Population Research Expert Review Group
Lewis, C. (Committee Member)
Jun 2011Activity: Other › Types of External academic engagement - Membership of peer review panel or committee
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PL o S Medicine (Journal)
Lewis, C. (Editorial board member)
2004 → …Activity: Publication peer-review and editorial work › Editorial activity
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Human Heredity (Journal)
Lewis, C. (Editorial board member)
2003 → …Activity: Publication peer-review and editorial work › Editorial activity