Research output per year
Research output per year
Personal profile
Research interests
The primary focus of my research program is on the biology and toxicology of minerals. In particular, I am interested in how metals and other minerals are regulated by organisms and how metals, primarily zinc, control biological processes. These studies include identification, function, and regulation of transporters and metal binding proteins as well as their respective genes.Present research interests concern functions of trace elements in health and disease, and molecular toxicology of environmental contaminants. Current research projects are (1) the roles of zinc and zinc-transporters in (a) development, (b) diabetes, (c) lipid metabolism, (d) epigenetic programming, and (e) gut epithelium maintenance; (2) regulation of dietary trace element uptake; and (3) in vitro methods to assess toxicity and bioaccumulation of contaminants. <br />
Research interests (short)
Biological functions of zinc and toxicology of environmental pollutants
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Assessment of information as regards the toxicity of deoxynivalenol for horses and poultry: EFSA Journal
Schrenk, D., Bignami, M., Bodin, L., del Mazo, J. K. C. J., Grasl-Kraupp, B., Hogstrand, C., Leblanc, J-C., Nielsen, E., Ntzani, E., Petersen, A., Sand, S., Schwerdtle, T., Vleminckx, C., Wallace, H., Dänicke, S., Nebbia, C. S., Oswald, I. P., Rovesti, E., Steinkellner, H., Hoogenboom, L., & 1 others, Feb 2023, In: EFSA J.. 21, 2, e07806.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Copper induces liver lipotoxicity disease by up-regulating Nrf2 expression via the activation of MTF-1 and inhibition of SP1/Fyn pathway
Zhong, C-C., Zhao, T., Hogstrand, C., Song, C-C., Zito, E., Tan, X-Y., Song, Y. F., Wei, X-L. & Luo, Z., 22 May 2023, In: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 1869, 6, 166752.Research output: Contribution to journal › Article › peer-review
Open Access -
Improving accuracy scores of neural network driven QSAR models of mutagenicity
Kalian, A., Osborne, O. J., Dorne, J-L. C. M., Gott, D., Potter, C., Guo, M. & Hogstrand, C., 18 Jul 2023, (E-pub ahead of print) In: Computer Aided Chemical Engineering. p. 2717-2722 6 p.Research output: Contribution to journal › Article › peer-review
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Risk assessment of N-nitrosamines in food: EFSA Journal
Schrenk, D., Bignami, M., Bodin, L., Chipman, J. K., del Mazo, J., Hogstrand, C., Hoogenboom, L., Leblanc, J-C., Nebbia, C. S., Nielsen, E., Ntzani, E., Petersen, A., Sand, S., Schwerdtle, T., Vleminckx, C., Wallace, H., Romualdo, B., Cristina, F., Stephen, H., Marco, I., & 5 others, Mar 2023, In: EFSA J.. 21, 3, e07884.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Risks for human health related to the presence of grayanotoxins in certain honey: EFSA Journal
Schrenk, D., Bignami, M., Bodin, L., Chipman, J. K., del Mazo, J., Grasl-Kraupp, B., Hogstrand, C., Hoogenboom, L., Leblanc, J-C., Nebbia, C. S., Nielsen, E., Ntzani, E., Petersen, A., Sand, S., Schwerdtle, T., Vleminckx, C., Dusemund, B., Hart, A., Mulder, P., Viviani, B., & 5 others, Mar 2023, In: EFSA J.. 21, 3, e07866.Research output: Contribution to journal › Article › peer-review
Open Access
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SPHERTOX: Hepatic 3D spheroids: the next generation of testing in toxicology (SPHERTOX)
1/09/2021 → 31/08/2025
Project: Research
Activities
- 1 Types of Award - Prize (including medals and awards)
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ZnT8: from molecular structure to function and back again
Christer Hogstrand (Recipient)
1 Mar 2015 → 29 Feb 2016Activity: Other › Types of Award - Prize (including medals and awards)