Christina Dunster

Christina Dunster

Mrs

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Personal profile

Research interests

I have extensive experience in the area of oxidative stress & free radicals and determining  the antioxidant status of healthy people and specific patient groups. 

These groups include those with respiratory diseases (asthmatics, COPD), pregnant women (pre-eclampsia,  Wellcome-VIP trial), and premature/full term births.   The sources of oxidative stress examined include  environmental factors (Particulate matter from indoor and outdoor sources, ozone, allergens, oxygen therapy in premature babies) or those occurring in situ  (inflammation, low vitamin status).  Additionally I have been involved in examining the impact of antioxidant supplementation, specifically vitamins C and E, in various patient groups (pre-eclampsia) or healthy subjects (BBC Horizon, MAFF), and alternatively,  the impact of patient treatment (in cystic fibrosis, asthma) on vitamin status.

My current work includes examining the chemical composition and oxidative potential of air pollution  in London and across the world.  Specifically, I am studying the respirable particulate matter  (PM10 and PM2.5) found in ambient air and by using an antioxidant depletion approach I  am determining their oxidative potential. This property we feel is an important factor in determining their impact on both healthy individuals, and those that are pre-disposed to the effects of this pollution (such as asthmatics).  In parallel, this information provides useful guidance on how Government policies could be introduced to reduce the most damaging types of pollution through measures such as the London Low Emmission Zone, or cleaner fuels. Techniques employed: HPLC-EC, GC-MS, enzyme kinetics, ELISA

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being
  • SDG 8 - Decent Work and Economic Growth
  • SDG 9 - Industry, Innovation, and Infrastructure
  • SDG 11 - Sustainable Cities and Communities
  • SDG 15 - Life on Land

Education/Academic qualification

Master of Philosophy, The Free Radical Reactions of Muconic Acid, Brunel University London

Award Date: 1 Jan 1993

Bachelor of Science, Biochemistry, Institute of Biology

Award Date: 1 Jan 1987

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