King's College London

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Dr Christine Bernsmeier

  1. Leucocyte ratios are biomarkers of mortality in patients with acute decompensation of cirrhosis and acute-on-chronic liver failure

    Bernsmeier, C., Cavazza, A., Fatourou, E. M., Theocharidou, E., Akintimehin, A., Baumgartner, B., Dhar, A., Auzinger, G., Thursz, M., Bernal, W., Wendon, J. A., Karvellas, C. J., Antoniades, C. G. & McPhail, M. J. W., 1 Sep 2020, In : Alimentary Pharmacology and Therapeutics. 52, 5, p. 855-865 11 p.

    Research output: Contribution to journalArticle

  2. Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis

    Brenig, R., Pop, O. T., Triantafyllou, E., Geng, A., Singanayagam, A., Perez-Shibayama, C., Besse, L., Cupovic, J., Künzler, P., Boldanova, T., Brand, S., Semela, D., Duong, F. H., Weston, C. J., Ludewig, B., Heim, M. H., Wendon, J., Antoniades, C. G. & Bernsmeier, C., 1 Jan 2020, In : Life Science Alliance. 3, 1, e201900465.

    Research output: Contribution to journalArticle

  3. Immunometabolic profiling of ascites from patients with acute-on-chronic liver failure reveals increased MerTK plus immunosuppressive myeloid cells and cell death markers with preferential lipid metabolism compared to cirrhosis without organ failure

    Singanayagam, A., Erminelli, D., Triantafyllou, E., Bernsmeier, C., Tunc, E., Krasniqi, M., Patel, V., Lebosse, F., Nathwani, R., Atkinson, A., Dhar, A., Heneghan, M., Auzinger, G., Khamri, W., Adams, D., Wendon, J., Thursz, M., McPhail, M. J. W. & Antoniades, H., Apr 2019, In : Journal of Hepatology. 70, p. E183-E183

    Research output: Contribution to journalMeeting Abstract

  4. PD-1+monocytes and macrophages contribute to impaired microbial clearance following acute liver failure

    Triantafyllou, E., Gudd, C., Nathwani, R., Trovato, F., Possamai, L., Morrison, R., Bernsmeier, C., Patel, V., Khamri, W., Goldin, R., Wendon, J., McPhail, M., Woollard, K., Thursz, M. & Antoniades, C., Apr 2019, In : Journal of Hepatology. 70, p. E430-E431

    Research output: Contribution to journalMeeting Abstract

  5. CD14+CD15-HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure

    Bernsmeier, C., Triantafyllou, E., Brenig, R., Lebosse, F. J., Singanayagam, A., Patel, V. C., Pop, O. T., Khamri, W., Nathwani, R., Tidswell, R., Weston, C. J., Adams, D. H., Thursz, M. R., Wendon, J. A. & Antoniades, C. G., Jun 2018, In : Gut. 67, 6, p. 1155-1167

    Research output: Contribution to journalArticle

  6. PLASMA S100A8/A9: A NOVEL MECHANISTIC BIOMARKER IN INNATE IMMUNE ACTIVATION IN ACUTE-ON-CHRONIC LIVER FAILURE

    Singanayagam, A., Nathwani, R., Triantafyllou, E., Patel, V. C., Dhar, A., McPhail, M., Bernsmeier, C., Wendon, J. & Antoniades, C. G., Jun 2018, In : Gut. 67, p. A131-A132

    Research output: Contribution to journalMeeting Abstract

  7. MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure

    Triantafyllou, E., Pop, O. T., Possamai, L. A., Wilhelm, A., Liaskou, E., Singanayagam, A., Bernsmeier, C., Khamri, W., Petts, G., Dargue, R., Davies, S. P., Tickle, J., Yuksel, M., Patel, V. C., Abeles, R. D., Stamataki, Z., Curbishley, S. M., Ma, Y., Wilson, I. D., Coen, M. & 7 others, Woollard, K. J., Quaglia, A., Wendon, J., Thursz, M. R., Adams, D. H., Weston, C. J. & Antoniades, C. G., Feb 2018, In : Gut. 67, 2, p. 333-347 15 p.

    Research output: Contribution to journalArticle

  8. Increased Expression of CTLA4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure

    Khamri, W., Abeles, R. D., Hou, T. Z., Anderson, A. E., El-Masry, A., Triantafyllou, E., Bernsmeier, C., Larsen, F. S., Singanayagam, A., Kudo, N., Possamai, L. A., Lebosse, F., Auzinger, G., Bernal, W., Willars, C., Weston, C. J., Lombardi, G., Wendon, J., Thursz, M. & Antoniades, C. G., 28 Mar 2017, In : Gastroenterology. 153, p. 263-276 e8.

    Research output: Contribution to journalArticle

  9. Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase

    Vergis, N., Khamri, W., Beale, K., Sadiq, F., Aletrari, M. O., Moore, C., Atkinson, S. R., Bernsmeier, C., Possamai, L. A., Petts, G., Ryan, J. M., Abeles, R. D., James, S., Foxton, M., Hogan, B., Foster, G. R., O'Brien, A. J., Ma, Y., Shawcross, D. L., Wendon, J. A. & 2 others, Antoniades, C. G. & Thursz, M. R., 9 Feb 2016, In : Gut.

    Research output: Contribution to journalArticle

  10. Neutrophil toll-like receptor 9 expression and the systemic inflammatory response in acetaminophen-induced acute liver failure

    Manakkat Vijay, G. K., Ryan, J. M., Abeles, R. D., Ramage, S., Patel, V., Bernsmeier, C., Riva, A., McPhail, M. J. W., Tranah, T. H., Markwick, L. J. L., Taylor, N. J., Bernal, W., Auzinger, G., Willars, C., Chokshi, S., Wendon, J. A., Ma, Y. & Shawcross, D. L., 1 Jan 2016, In : Critical Care Medicine. 44, 1, p. 43-53 11 p.

    Research output: Contribution to journalArticle

  11. High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial

    Larsen, F. S., Schmidt, L. E., Bernsmeier, C., Rasmussen, A., Isoniemi, H., Patel, V., Triantafyllou, E., Bernal, W., Auzinger, G., Shawcross, D., Eefsen, M., Bjerring, P. N., Clemmesen, J. O., Hockerstedt, K., Frederiksen, H-J., Hansen, B. A., Antoniades, C. G. & Wendon, J., Jan 2016, In : Journal of Hepatology. p. 590-595 6 p.

    Research output: Contribution to journalArticle

  12. Altered gut microbial profile is a proponent of bacterial translocation in acute-on-chronic liver failure

    Patel, V. C., Leong, L. E. X., Koller, G., Knapp, S., Lai, G., Singanayagam, A., Bernsmeier, C., McPhail, M. J. W., Shawcross, D. L., Antoniades, C. G., Thursz, M., Wendon, J. A., Rogers, G. B. & Bruce, K. D., 2016, J Hepatol. p. S453-S454 (J Hepatol; vol. 64).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  13. Immunotherapy in the treatment and prevention of infection in acute-on-chronic liver failure

    Bernsmeier, C., Singanayagam, A., Patel, V. C., Wendon, J. A. & Antoniades, C. G., 12 Jun 2015, In : Immunotherapy. 14 p.

    Research output: Contribution to journalArticle

  14. Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK

    Bernsmeier, C., Pop, O. T., Singanayagam, A., Triantafyllou, E., Patel, V. C., Weston, C. J., Curbishley, S., Sadiq, F., Vergis, N., Khamri, W., Bernal, W., Auzinger, G., Heneghan, M., Ma, Y., Jassem, W., Heaton, N. D., Adams, D. H., Quaglia, A., Thursz, M. R., Wendon, J. & 1 others, Antoniades, C. G., Mar 2015, In : Gastroenterology. 148, 3, p. 603-615.e14 27 p.

    Research output: Contribution to journalArticle

  15. Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure

    Antoniades, C. G., Khamri, W., Abeles, R. D., Taams, L. S., Triantafyllou, E., Possamai, L. A., Bernsmeier, C., Mitry, R. R., O'Brien, A., Gilroy, D., Goldin, R., Heneghan, M., Heaton, N., Jassem, W., Bernal, W., Vergani, D., Ma, Y., Quaglia, A., Wendon, J. & Thursz, M., 1 Apr 2014, In : Hepatology. 59, 4, p. 1564-1576 13 p.

    Research output: Contribution to journalArticle

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