Search results

• Finished

  Feasibility of the safe withdrawal of inhaled corticosteroids in patients with mild to moderate COPD prescribed outside guidelines

  White, P. (Primary Investigator), Corrigan, C. (Co-Investigator), Harries, T. (Co-Investigator), Moxham, J. (Co-Investigator), Schofield, P. (Co-Investigator), Sethi, T. (Co-Investigator) & Wright, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  29/08/2017 → 30/06/2019

  Project: Research

• Does sphingosine-1-phosphate constrict human airways? In-vivo challenge pilot study

  Woszczek, G. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  KHP King's Health Partners

  23/08/2017 → 22/02/2022

  Project: Research

• NIHR Biomedical Research Centre. Funding for Financial Years 2017/18, 2018/19

  Wolfe, C. (Primary Investigator), Parsons, M. (Primary Investigator), Gould, H. (Primary Investigator), Corrigan, C. (Primary Investigator), Greenough, A. (Primary Investigator), Peakman, M. (Primary Investigator), Vyse, T. (Primary Investigator), Antoniou, M. (Primary Investigator), Oakey, R. (Primary Investigator), McGrath, J. (Primary Investigator), Karagiannis, S. (Primary Investigator), Barker, J. (Primary Investigator), Flohr, C. (Primary Investigator), Tziotzios, C. (Primary Investigator), Whittaker, S. (Primary Investigator), Spector, T. (Primary Investigator), Watt, F. (Primary Investigator), Hayday, A. (Primary Investigator), Spencer, J. (Primary Investigator), Cope, A. (Primary Investigator), Malim, M. (Primary Investigator), Martin Serrano, J. (Primary Investigator), Edgeworth, J. (Primary Investigator), Cason, J. (Primary Investigator), Lord, G. (Primary Investigator), Dorling, A. (Primary Investigator), Sacks, S. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Lombardi, G. (Primary Investigator), Ostermann, M. (Primary Investigator), Shah, A. (Primary Investigator), Marber, M. (Primary Investigator), Mayr, M. (Primary Investigator), Chowienczyk, P. (Primary Investigator), Wells, C. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Sawyer, E. (Primary Investigator), Maher, J. (Primary Investigator), Tribe, R. (Primary Investigator), Ilic, D. (Primary Investigator), Poston, L. (Primary Investigator), Rutherford, M. (Primary Investigator), Gee, T. (Primary Investigator), Blower, P. (Primary Investigator), Edwards, D. (Primary Investigator), Sharpe, P. (Primary Investigator), Streit, A. (Primary Investigator), Naglik, J. (Primary Investigator), Tavassoli, M. (Primary Investigator) & McNaughton, P. (Primary Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2017 → 31/03/2022

  Project: Research

  • Biomedical Research 100%

• Development of a novel therapeutic for inflammatory lung disorders

  Corrigan, C. (Primary Investigator) & Ward, J. (Co-Investigator)

  1/01/2016 → 31/12/2019

  Project: Research

• Genetic and Functional Characterization of the IgE Repertoire and Compartmental Regulation of IgE Activity in the Pathogenesis of Asthma

  Gould, H. (Primary Investigator), Corrigan, C. (Co-Investigator), Tindall, L. (Co-Investigator) & Wu, B. (Co-Investigator)

  MRC Medical Research Council

  15/12/2015 → 14/12/2018

  Project: Research

• The sphingosine-1-phosphate/ sphingosine kinase pathway in asthma pathogenesis

  Woszczek, G. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  7/12/2015 → 6/12/2018

  Project: Research

• A proof-of-concept study for a novel COPD treatment

  Ward, J. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  1/07/2015 → 30/06/2016

  Project: Research

• Bronchoconstricting activity of sphingosine-1-phosphate in asthma

  Woszczek, G. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  1/05/2015 → 30/04/2016

  Project: Research

• UK Refractory Asthma Stratification Programme (RASP-UK)

  Corrigan, C. (Primary Investigator)

  MRC Medical Research Council

  1/04/2015 → 31/03/2020

  Project: Research

• Genetic and functional characterisation of the IgE repertoire and compartmental regulation of IgE activity in the pathogenesis and treatment of asthma

  Gould, H. (Primary Investigator), Corrigan, C. (Co-Investigator), Tindall, L. (Co-Investigator) & Wu, B. (Co-Investigator)

  1/09/2014 → 31/08/2019

  Project: Research

• Role of glycosaminoglycans upon human airway smooth muscle remodelling in asthma - investigation of cell-extracellular matrix interactions

  Page, C. (Primary Investigator), Corrigan, C. (Co-Investigator) & Kanabar-Raivadera, V. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Defining immune phenotypes in steroid sensitive and steroid refractory asthma patients, and how this is altered by vitamin D: in vitro and in vivo investigations

  Hawrylowicz, C. (Primary Investigator), Corrigan, C. (Co-Investigator) & Lavender, P. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• The role of ER stress in asthmatic allergen sensitisation and IgE synthesis

  Corrigan, C. (Primary Investigator)

  1/10/2013 → 30/09/2015

  Project: Research

• IL-25 and its signalling pathways: key molecular targets for inhibition of airways remodelling in human asthma

  Sun, Y. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  15/01/2013 → 14/01/2016

  Project: Research

• Can vitamin D protect the airways from inflammation due to particulate matter air pollution that would otherwise drive asthma

  Hawrylowicz, C. (Primary Investigator), Pfeffer, P. (Primary Investigator), Corrigan, C. (Co-Investigator) & Kelly, F. (Co-Investigator)

  1/10/2012 → 30/09/2014

  Project: Research

• Can vitamin D reduce airway inflammation after injury by particulate matter air pollution

  Hawrylowicz, C. (Primary Investigator), Corrigan, C. (Co-Investigator) & Kelly, F. (Co-Investigator)

  1/10/2012 → 30/09/2014

  Project: Research

• Identification of predictive biomarkers of the long-term efficacy of specific immunotherapy for allergic rhinitis

  Turcanu, V. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  1/10/2012 → 30/09/2015

  Project: Research

• Can vitamin D protect airways from inflammation due to particulate matter air pollution that would otherwise drive asthma?

  Hawrylowicz, C. (Primary Investigator), Corrigan, C. (Co-Investigator), Kelly, F. (Co-Investigator) & Pfeffer, P. (Co-Investigator)

  Wellcome Trust

  1/10/2012 → 8/10/2014

  Project: Research

• IL-25-induced airways remodelling in human asthma and animal surrogates: effects of PI3K inhibitors (Senior Investigator Award)

  Corrigan, C. (Primary Investigator) & Sun, Y. (Co-Investigator)

  1/03/2012 → 28/02/2017

  Project: Research

• Characterisation of predictive biomarkers of allergen-specific immunotherapy efficacy

  Turcanu, V. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  1/10/2011 → 30/09/2014

  Project: Research

• Polycations and the calcium-sensing receptor (CaSR) in asthma

  Corrigan, C. (Primary Investigator) & Ward, J. (Primary Investigator)

  Asthma UK

  1/10/2011 → 30/09/2013

  Project: Research

• Differential production and regulation of IL-17 in steroid sensitive and refractory asthma

  Corrigan, C. (Primary Investigator) & Hawrylowicz, C. (Primary Investigator)

  Asthma UK

  1/10/2011 → 30/09/2012

  Project: Research

• The role of IL-25 in airways remodelling in asthma

  Sun, Y. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  1/07/2011 → 30/06/2013

  Project: Research

• Smooth muscle stimulation by platelets taken from asthmatic individuals

  Pitchford, S. (Primary Investigator), Corrigan, C. (Co-Investigator), Liu, S. (Co-Investigator) & Page, C. (Co-Investigator)

  1/10/2010 → 30/09/2013

  Project: Research

• Studies of aberrant B cell biology in non-atopic asthma

  Corrigan, C. (Primary Investigator) & Gould, H. (Primary Investigator)

  Novartis Pharmaceuticals UK Ltd

  1/10/2010 → 30/09/2013

  Project: Research

• Personal discretionary award

  Corrigan, C. (Primary Investigator)

  1/09/2010 → 31/08/2015

  Project: Research

• Receptor revision in the bronchial mucosa in the pathegenesis of asthma

  Gould, H. (Primary Investigator), Corrigan, C. (Co-Investigator) & Takhar, P. (Co-Investigator)

  1/07/2010 → 30/06/2013

  Project: Research

• A randomised, double-blind, placebo-controlled study to evaluate the efficacy of oral azithromycin (500mg OD) as a supplement to the standard care for patients with acute exacerbrations of asthma

  Corrigan, C. (Primary Investigator)

  1/06/2010 → 31/05/2012

  Project: Research

• Role of IgE in the pathogenesis of non-atopic asthma

  Gould, H. (Primary Investigator), Corrigan, C. (Co-Investigator), Lee, T. (Co-Investigator), Sun, Y. (Co-Investigator) & Takhar, P. (Co-Investigator)

  Wellcome Trust

  1/06/2010 → 31/08/2014

  Project: Research

• The role of the local IgE in the aetiology of non-atopic asthma

  Corrigan, C. (Primary Investigator), Beavil, A. (Co-Investigator), Gould, H. (Co-Investigator), Lee, T. (Co-Investigator) & Sun, Y. (Co-Investigator)

  4/01/2010 → 3/01/2015

  Project: Research

• Genome-wide profiling of asthmatic airway smooth muscle.

  Corrigan, C. (Primary Investigator), Cousins, D. (Primary Investigator) & Woszczek, G. (Primary Investigator)

  1/10/2009 → 30/09/2010

  Project: Research

• The role of IL-25 in airways remodelling in asthma: effects on fibroblasts and endothelial cells

  Sun, Y. (Primary Investigator) & Corrigan, C. (Co-Investigator)

  Asthma UK

  1/10/2009 → 30/09/2010

  Project: Research

• The role of IL-25 in airways remodelling in asthma

  Corrigan, C. (Primary Investigator) & Sun, Y. (Primary Investigator)

  1/10/2009 → 30/09/2012

  Project: Research

• Receptor revision in the bronchial mucosa in allergic asthma

  Gould, H. (Primary Investigator), Corrigan, C. (Co-Investigator) & Takhar, P. (Co-Investigator)

  1/10/2009 → 30/09/2010

  Project: Research

• Comprehensive transcriptome analysis of cells in the asthmatic lung

  Lee, T. (Primary Investigator), Corrigan, C. (Co-Investigator) & Cousins, D. (Co-Investigator)

  1/09/2009 → 31/08/2014

  Project: Research

• Effects of environmental tobacco smoke (ETS) on airways inflammation and remodelling in asthma

  Corrigan, C. (Primary Investigator), Lee, T. (Co-Investigator) & Sun, Y. (Co-Investigator)

  1/04/2009 → 31/03/2012

  Project: Research

• The effect of a humanised monoclonal anti-IgE antibody (omalizumab) on disease control and bronchial mucosal inflammation in non-atopic (intrinsic) asthma

  Corrigan, C. (Primary Investigator), Gould, H. (Co-Investigator), Sun, Y. (Co-Investigator) & Takhar, P. (Co-Investigator)

  Guy's & St Thomas' Charity

  1/03/2009 → 31/07/2013

  Project: Research

• Modification of the t cell response to mycobacterium tuberculosis by intestinal helminth infection renders individuals more susceptible to active tuberculosis

  Corrigan, C. (Primary Investigator) & academic, A. (Primary Investigator)

  1/03/2009 → 29/02/2012

  Project: Research

• Real time imaging of Eosinophil and neutrophil migration in healthy volunteers and asthmatics

  Mullen, G. (Primary Investigator), Blower, P. (Co-Investigator), Corrigan, C. (Co-Investigator), Lee, T. (Co-Investigator), O'Doherty, M. (Co-Investigator) & academic, A. (Co-Investigator)

  1/02/2009 → 31/01/2012

  Project: Research

• Receptor revision in the asthmatic bronchial mucosa: a new target for therapy

  Gould, H. (Primary Investigator), Corrigan, C. (Co-Investigator), Lee, T. (Co-Investigator) & Takhar, P. (Co-Investigator)

  5/01/2009 → 4/01/2012

  Project: Research

• Understanding defective gene regulation by glucocorticoids in asthma.

  Corrigan, C. (Primary Investigator), Hawrylowicz, C. (Primary Investigator) & Lavender, P. (Primary Investigator)

  1/10/2008 → 30/09/2010

  Project: Research

• The signicance of RAG expression in the bronchial mucosa in asthma

  Takhar, P. (Primary Investigator), Corrigan, C. (Co-Investigator), Gould, H. (Co-Investigator) & Lee, T. (Co-Investigator)

  1/10/2008 → 30/09/2011

  Project: Research

• The effect of an anti-IgE antibody (omalizumab) on disease control and bronchial mucosal in flammation in non-atopic asthma

  Corrigan, C. (Primary Investigator), Gould, H. (Primary Investigator), Lee, T. (Primary Investigator) & Sun, Y. (Primary Investigator)

  1/10/2008 → 30/09/2011

  Project: Research

• Does 1x, 25-dihydroxyvitamin D 3 enhance corticosteroid activity in steroid-refractory asthma?

  Corrigan, C. (Primary Investigator) & Hawrylowicz, C. (Primary Investigator)

  Asthma UK

  1/10/2008 → 31/01/2013

  Project: Research

• The effect of a humanised monoclonal anti-IgE antibody (omalizumab) in disease control and bronchial mucosal inflammation in non-atopic asthma

  Corrigan, C. (Primary Investigator), Lee, T. (Primary Investigator), Sun, Y. (Primary Investigator), Chung, F. (Co-Investigator), Durham, S. (Co-Investigator) & Gould, H. (Co-Investigator)

  1/10/2008 → 30/09/2011

  Project: Research

• Can Vitamn D improve the clinical resonse to steroids in sever steroid insensitive asthma?

  Corrigan, C. (Primary Investigator) & Hawrylowicz, C. (Primary Investigator)

  1/04/2008 → 30/09/2009

  Project: Research

• The use of surface parasternal intercostal muscle electromyogram recordings (EMGps) to assess disease severity in paediatric and adult asthma

  Corrigan, C. (Primary Investigator), Moxham, J. (Primary Investigator), Greenough, A. (Co-Investigator), Kanabar, D. (Co-Investigator) & Rafferty, G. (Co-Investigator)

  Guy's & St Thomas' Charity

  1/01/2008 → 29/02/2012

  Project: Research

• Pharmacological induction of allergen-specific IL-10-secreting regulatory cells in allergy and asthma

  Hawrylowicz, C. (Primary Investigator), Corrigan, C. (Co-Investigator) & Ryanna, K. (Co-Investigator)

  MRC Medical Research Council

  1/10/2007 → 30/09/2010

  Project: Research

• Crosstalk between eosinophilis and Th2 memory cells augments allergic lung inflammation

  Corrigan, C. (Primary Investigator) & Sun, Y. (Primary Investigator)

  Dana Foundation

  1/07/2007 → 31/12/2010

  Project: Research

• NIHR Biomedical Research Centre

  Afzali, B. (Primary Investigator), Antoniou, M. (Primary Investigator), Barker, J. (Primary Investigator), Barratt, B. (Primary Investigator), Beighton, D. (Primary Investigator), Bevan, S. (Primary Investigator), Blower, P. (Primary Investigator), Burchell, J. (Primary Investigator), Cason, J. (Primary Investigator), Chappell, L. (Primary Investigator), Cope, A. (Primary Investigator), Corrigan, C. (Primary Investigator), Cunninghame Graham, D. (Primary Investigator), Dontu, G. (Primary Investigator), Edgeworth, J. (Primary Investigator), Farzaneh, F. (Primary Investigator), Gee, T. (Primary Investigator), Gould, H. (Primary Investigator), Green, P. (Primary Investigator), Greenough, A. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Hayday, A. (Primary Investigator), Higginson, I. (Primary Investigator), Kalra, L. (Primary Investigator), Karagiannis, S. (Primary Investigator), Kelly, F. (Primary Investigator), Kemper, C. (Primary Investigator), Lau-Walker, M. (Primary Investigator), Lavender, P. (Primary Investigator), Lee, T. (Primary Investigator), Lempp, H. (Primary Investigator), Lewis, C. (Primary Investigator), Lombardi, G. (Primary Investigator), Lord, G. (Primary Investigator), Marber, M. (Primary Investigator), Mason, J. (Primary Investigator), Mathew, C. (Primary Investigator), McGrath, J. (Primary Investigator), Metcalfe, A. (Primary Investigator), Molokhia, M. (Primary Investigator), Mullen, G. (Primary Investigator), Nagel, E. (Primary Investigator), Neil, S. (Primary Investigator), Nestle, F. (Primary Investigator), Oakey, R. (Primary Investigator), Parker, P. (Primary Investigator), Peakman, M. (Primary Investigator), Perera, D. (Primary Investigator), Purushotham, A. (Primary Investigator), Rasekh Ahmadi, K. (Primary Investigator), Rashid, T. (Primary Investigator), Razavi, R. (Primary Investigator), Ridley, A. (Primary Investigator), Robson, M. (Primary Investigator), Sacks, S. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Santis, G. (Primary Investigator), Sanz Moreno, V. (Primary Investigator), Sawyer, E. (Primary Investigator), Schaeffter, T. (Primary Investigator), Shah, A. (Primary Investigator), Sharpe, P. (Primary Investigator), Simpson, M. (Primary Investigator), Smith, R. (Primary Investigator), Sorinola, I. (Primary Investigator), Spector, T. (Primary Investigator), Spicer, J. (Primary Investigator), Taams, L. (Primary Investigator), Tavassoli, M. (Primary Investigator), Taylor, D. (Primary Investigator), Tree, T. (Primary Investigator), Trembath, R. (Primary Investigator), Tribe, R. (Primary Investigator), Tutt, A. (Primary Investigator), Waltham, M. (Primary Investigator), Watt, F. (Primary Investigator), Webb, A. (Primary Investigator), Wells, C. (Primary Investigator), Whelan, K. (Primary Investigator), Whitaker, J. (Primary Investigator), Whittlesea, C. (Primary Investigator), Williamson, C. (Primary Investigator), Wolfe, C. (Primary Investigator), Yu, V. (Primary Investigator), academic, A. (Primary Investigator), Hughes, S. (Co-Investigator), Montana, G. (Co-Investigator), Rhode, K. (Co-Investigator), Schnabel, J. (Co-Investigator) & Tziotzios, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research, DHSC Department of Health and Social Care

  1/04/2007 → 31/03/2017

  Project: Research

  • T-Helper Cell 100%
  • Inflammatory Arthritis 66%
  • Interleukin 17 66%
  • T Cell 44%
  • Interleukin 10 41%