King's College London

Research portal

Dr Christopher Huebel

  1. Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

    Coleman, J. R. I., Peyrot, W. J., Purves, K., Davis, K. A. S., Rayner, C., Choi, S. W., Huebel, C., Gaspar, H. A., Kan, C., der Auwera, S. V., Adams, M. J., Lyall, D., Choi, K. W., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Dunn, E. C., Vassos, E., Danese, A., Maughan, B., Grabe, H. J., Lewis, C. M. & 7 others, O'Reilly, P. F., McIntosh, A. M., Smith, D. J., Wray, N. R., Hotopf, M., Eley, T. C. & Breen, G., 23 Jan 2020, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  2. A longitudinal study of eating behaviours in childhood and later eating disorder behaviours and diagnoses

    Herle, M., De Stavola, B., Huebel, C., Abdulkadir, M., Santos Ferreira, D. L., Loos, R. J. F., Bryant-Waugh, R., Bulik, C. M. & Micali, N., 1 Jan 2020, In : British Journal of Psychiatry. 216, 2, p. 113-119 7 p.

    Research output: Contribution to journalArticle

  3. The Genetic Links to Anxiety and Depression (GLAD) Study: Online recruitment into the largest recontactable study of depression and anxiety

    Davies, M. R., Kalsi, G., Armour, C., Jones, I., McIntosh, A., Smith, D. J., Walters, J. T. R., Bradley, J. R., Kingston, N., Ashford, S., Beange, I., Brailean, A., Cleare, A. J., Coleman, J. R. I., Curtis, C. J., Curzons, S. C. B., Davis, K. A. S., Downey, L., Gault, V., Goldsmith, K. A. & 27 others, Hammond Bennett, M., Hirose, Y., Hotopf, M. H., Huebel, C., Leng, J., Mason, B. D., McAtarsney-Kovacs, M., Monssen, D., Palaiologou, E., Pariante, C. M., Parikh, S., Peel, A., Price, R., Rimes, K. A., Rogers, H. C., Skelton, M., Spaul, A., Almira Suarez, E. L., Sykes, B. L., Thomas, K., Young, A., Vassos, E., Veale, D., White, K. M., Wingrove, J., Eley, T. C. & Breen, G. D., 1 Dec 2019, In : Behaviour Research and Therapy. 123, 103503.

    Research output: Contribution to journalArticle

  4. Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Dec 2019, In : Translational psychiatry. 9, 1, p. 117 117.

    Research output: Contribution to journalArticle

  5. Body composition in anorexia nervosa: meta-analysis and meta-regression of cross-sectional and longitudinal studies

    Huebel, C., Yilmaz, Z., Schaumberg, K., Breithaupt, L., Hunjan, A. K., García-gonzález, J., O'Reilly, P. F., Bulik, C. M. & Breen, G. D., 1 Nov 2019, In : The International journal of eating disorders. 52, 11, p. 1205-1223 19 p.

    Research output: Contribution to journalReview article

  6. Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches

    Eating Disorders Working Group of the Psychiatric Genomics Consortium, 15 Oct 2019, In : Biological psychiatry. 86, 8, p. 577-586 10 p.

    Research output: Contribution to journalArticle

  7. Indicators of Mental Disorders in UK Biobank – A comparison of approaches

    Davis, K. A. S., Cullen, B., Adams, M. J., Brailean, A., Breen, G. D., Coleman, J. R. I., Dregan, A., Gaspar, H. A., Huebel, C., Lee, W., McIntosh, A. M., Nolan, J., Pearsall, R. & Hotopf, M., 1 Sep 2019, In : International Journal of Methods in Psychiatric Research. 28, 3, e1796.

    Research output: Contribution to journalArticle

  8. Associations between blood metabolic profile at 7 years old and eating disorders in adolescence: Findings from the avon longitudinal study of parents and children

    Ferreira, D. L. S., Hübel, C., Herle, M., Abdulkadir, M., Loos, R. J. F., Bryant-Waugh, R., Bulik, C. M., De Stavola, B. L., Lawlor, D. A. & Micali, N., Sep 2019, In : Metabolites. 9, 9, p. 1-16 191.

    Research output: Contribution to journalArticle

  9. Genomics of body fat percentage may contribute to sex bias in anorexia nervosa

    Hübel, C., Gaspar, H. A., Coleman, J. R. I., Finucane, H., Purves, K. L., Hanscombe, K. B., Prokopenko, I., MAGIC Investigators, Graff, M., Workalemahu, T., Ngwa, J. S., Eating Disorder Working Group of the Psychiatric Genomics Consortium, O'Reilly, P. F., Bulik, C. M. & Breen, G., Sep 2019, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 180, 6, p. 428-438 11 p.

    Research output: Contribution to journalArticle

  10. Accepted/In press

    A major role for common genetic variation in anxiety disorders

    Purves, K., Coleman, J. R. I., Meier, S. M., Rayner, C. D., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Choi, S. W., Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M. H., Hougaard, D. M., Huebel, C., Kan, C., McIntosh, A. M., Mors, O., Mortensen, P. B. & 6 others, Nordentoft, M., Werge, T., Nicodemus, K. K., Mattheisen, M., Breen, G. D. & Eley, T. C., 19 Aug 2019, (Accepted/In press) In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  11. Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

    Anorexia Nervosa Genetics Initiative, Aug 2019, In : Nature Genetics. 51, 8, p. 1207–1214 8 p.

    Research output: Contribution to journalArticle

  12. Obesity remodels activity and transcriptional state of a lateral hypothalamic brake on feeding

    Rossi, M. A., Basiri, M. L., McHenry, J. A., Kosyk, O., Otis, J. M., van den Munkhof, H. E., Bryois, J., Hübel, C., Breen, G., Guo, W., Bulik, C. M., Sullivan, P. F. & Stuber, G. D., 28 Jun 2019, In : Science. 364, 6447, p. 1271-1274 4 p.

    Research output: Contribution to journalArticle

  13. Increased lipid and lipoprotein concentrations in anorexia nervosa: A systematic review and meta-analysis

    Hussain, A. A., Hübel, C., Hindborg, M., Lindkvist, E., Kastrup, A. M., Yilmaz, Z., Støving, R. K., Bulik, C. M. & Sjögren, J. M., 1 Jun 2019, In : The International journal of eating disorders. 52, 6, p. 611-629 19 p.

    Research output: Contribution to journalReview article

  14. Accepted/In press
  15. BIOLOGICAL PATHWAYS AND DRUG GENE-SETS: ANALYSIS AND VISUALIZATION

    Gaspar, H. A., Hubel, C. & Breen, G., 2019, In : European Neuropsychopharmacology. 29, p. S834-S834

    Research output: Contribution to journalMeeting Abstract

  16. Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent

    Huebel, C., Gaspar, H. A., Coleman, J. R. I., Hanscombe, K. B., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Purves, K., Prokopenko, I., The MAGIC Investigators, O'Reilly, P. F., Bulik, C. M. & Breen, G. D., 2019, In : Nature Communications. 10, 1, 5765 .

    Research output: Contribution to journalArticle

  17. Epigenetics in eating disorders: a systematic review

    Hübel, C., Marzi, S. J., Breen, G. & Bulik, C. M., 23 Oct 2018, In : Molecular Psychiatry.

    Research output: Contribution to journalReview article

  18. Bidirectional relationship between eating disorders and autoimmune diseases

    Hedman, A., Breithaupt, L., Hübel, C., Thornton, L. M., Tillander, A., Norring, C., Birgegård, A., Larsson, H., Ludvigsson, J. F., Sävendahl, L., Almqvist, C. & Bulik, C. M., 3 Sep 2018, In : Journal of child psychology and psychiatry.

    Research output: Contribution to journalArticle

  19. Rigor and reproducibility in genetic research on eating disorders

    Hübel, C., Leppä, V., Breen, G. & Bulik, C. M., Jul 2018, In : The International journal of eating disorders. 51, 7, p. 593-607 15 p.

    Research output: Contribution to journalReview article

  20. Updates on Genome-Wide Association Findings in Eating Disorders and Future Application to Precision Medicine

    Breithaupt, L., Hubel, C. & Bulik, C. M., 2018, In : Current Neuropharmacology. 16, 8, p. 1102-1110 9 p.

    Research output: Contribution to journalReview article

  21. The Science Behind the Academy for Eating Disorders' Nine Truths About Eating Disorders

    Schaumberg, K., Welch, E., Breithaupt, L., Hübel, C., Baker, J. H., Munn-Chernoff, M. A., Yilmaz, Z., Ehrlich, S., Mustelin, L., Ghaderi, A., Hardaway, A. J., Bulik-Sullivan, E. C., Hedman, A. M., Jangmo, A., Nilsson, I. A. K., Wiklund, C., Yao, S., Seidel, M. & Bulik, C. M., Nov 2017, In : European Eating Disorders Review. 25, 6, p. 432-450 19 p.

    Research output: Contribution to journalReview article

  22. Translating genome-wide association findings into new therapeutics for psychiatry

    Breen, G., Li, Q., Roth, B. L., O'donnell, P., Didriksen, M., Dolmetsch, R., O'reilly, P. F., Gaspar, H. A., Manji, H., Huebel, C., Kelsoe, J. R., Malhotra, D., Bertolino, A., Posthuma, D., Sklar, P., Kapur, S., Sullivan, P. F., Collier, D. A. & Edenberg, H. J., Nov 2016, In : Nature Neuroscience. 19, 11, p. 1392-1396

    Research output: Contribution to journalArticle

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