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Christopher Mathew

Professor

 https://orcid.org/0000-0003-4178-1838
  • 46697
    Citations
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  • 2019

    IBD BioResource: An Open-Access Platform of 25 000 Patients to Accelerate Research in Crohn's and Colitis

    Parkes, M., Prescott, N., Mathew, C., Sanderson, J. & Irving, P., Sept 2019, In: Gut. 68, 9, p. 1537-1540

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    23 Citations (Scopus)
  • 2017

    Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

    de Lange, K. M., Moutsianas, L., Lee, J. C., Lamb, C. A., Luo, Y., Kennedy, N. A., Jostins, L., Rice, D. L., Gutierrez-Achury, J., Ji, S-G., Heap, G., Nimmo, E. R., Edwards, C., Henderson, P., Mowat, C., Sanderson, J., Satsangi, J., Simmons, A., Wilson, D. C., Tremelling, M., & 12 othersHart, A., Mathew, C. G., Newman, W. G., Parkes, M., Lees, C. W., Uhlig, H., Hawkey, C., Prescott, N. J., Ahmad, T., Mansfield, J. C., Anderson, C. A. & Barrett, J. C., 1 Feb 2017, In: Nature Genetics. 49, 2, p. 256-261

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    File
    665 Citations (Scopus)
    92 Downloads (Pure)
  • 2013

    Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis

    Fakiola, M., Strange, A., Cordell, H. J., Miller, E. N., Pirinen, M., Su, Z., Mishra, A., Mehrotra, S., Monteiro, G. R., Band, G., Bellenguez, C., Dronov, S., Edkins, S., Freeman, C., Giannoulatou, E., Gray, E., Hunt, S. E., Lacerda, H. G., Langford, C., Pearson, R., & 31 othersPontes, N. N., Rai, M., Singh, S. P., Smith, L., Sousa, O., Vukcevic, D., Bramon-Bosch, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Wilson, M. E., Deloukas, P., Peltonen, L., Christiansen, F., Witt, C., Jeronimo, S. M. B., Sundar, S., Spencer, C. C. A., Blackwell, J. M. & LeishGEN Consortium, 1 Feb 2013, In: Nature Genetics. 45, 2, p. 208-213 6 p.

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    File
    83 Citations (Scopus)
    150 Downloads (Pure)

  • Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

    Hunt, K. A., Mistry, V., Bockett, N. A., Ahmad, T., Ban, M., Barker, J. N., Barrett, J. C., Blackburn, H., Brand, O., Burren, O., Capon, F., Compston, A., Gough, S. C. L., Jostins, L., Kong, Y., Lee, J. C., Lek, M., MacArthur, D. G., Mansfield, J. C., Mathew, C. G., & 17 othersMein, C. A., Mirza, M., Nutland, S., Onengut-Gumuscu, S., Papouli, E., Parkes, M., Rich, S. S., Sawcer, S., Satsangi, J., Simmonds, M. J., Trembath, R. C., Walker, N. M., Wozniak, E., Todd, J. A., Simpson, M. A., Plagnol, V. & van Heel, D. A., 13 Jun 2013, In: NATURE. 498, 7453, p. 232-235 4 p.

    Research output: Contribution to journal › Letter › peer-review

    158 Citations (Scopus)
  • 2012

    Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

    Hunt, K. A., Smyth, D. J., Balschun, T., Ban, M., Mistry, V., Ahmad, T., Anand, V., Barrett, J. C., Bhaw-Rosun, L., Bockett, N. A., Brand, O. J., Brouwer, E., Concannon, P., Cooper, J. D., Dias, K-R. M., van Diemen, C. C., Dubois, P. C., Edkins, S., Foelster-Holst, R., Fransen, K., & 45 othersGlass, D. N., Heap, G. A. R., Hofmann, S., Huizinga, T. W. J., Hunt, S., Langford, C., Lee, J., Mansfield, J., Marrosu, M. G., Mathew, C. G., Mein, C. A., Mueller-Quernheim, J., Nutland, S., Onengut-Gumuscu, S., Ouwehand, W., Pearce, K., Prescott, N. J., Posthumus, M. D., Potter, S., Rosati, G., Sambrook, J., Satsangi, J., Schreiber, S., Shtir, C., Simmonds, M. J., Sudman, M., Thompson, S. D., Toes, R., Trynka, G., Vyse, T. J., Walker, N. M., Weidinger, S., Zhernakova, A., Zoledziewska, M., Weersma, R. K., Gough, S. C. L., Sawcer, S., Wijmenga, C., Parkes, M., Cucca, F., Franke, A., Deloukas, P., Rich, S. S., Todd, J. A. & van Heel, D. A., Jan 2012, In: Nature Genetics. 44, 1, p. 3 - 5 3 p.

    Research output: Contribution to journal › Letter › peer-review

    36 Citations (Scopus)
  • 2011

    Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Sawcer, S., Hellenthal, G., Pirinen, M., Spencer, C. C. A., Patsopoulos, N. A., Moutsianas, L., Dilthey, A., Su, Z., Freeman, C., Hunt, S. E., Edkins, S., Gray, E., Booth, D. R., Potter, S. C., Goris, A., Band, G., Oturai, A. B., Strange, A., Saarela, J., Bellenguez, C., & 222 othersFontaine, B., Gillman, M., Hemmer, B., Gwilliam, R., Zipp, F., Jayakumar, A., Martin, R., Leslie, S., Hawkins, S., Giannoulatou, E., D'alfonso, S., Blackburn, H., Boneschi, F. M., Liddle, J., Harbo, H. F., Perez, M. L., Spurkland, A., Waller, M. J., Mycko, M. P., Ricketts, M., Comabella, M., Hammond, N., Kockum, I., McCann, O. T., Ban, M., Whittaker, P., Kemppinen, A., Weston, P., Hawkins, C., Widaa, S., Zajicek, J., Dronov, S., Robertson, N., Bumpstead, S. J., Barcellos, L. F., Ravindrarajah, R., Abraham, R., Alfredsson, L., Ardlie, K., Aubin, C., Baker, A., Baker, K., Baranzini, S. E., Bergamaschi, L., Bergamaschi, R., Bernstein, A., Berthele, A., Boggild, M., Bradfield, J. P., Brassat, D., Broadley, S. A., Buck, D., Butzkueven, H., Capra, R., Carroll, W. M., Cavalla, P., Celius, E. G., Cepok, S., Chiavacci, R., Clerget-Darpoux, F., Clysters, K., Comi, G., Cossburn, M., Cournu-Rebeix, I., Cox, M. B., Cozen, W., Cree, B. A. C., Cross, A. H., Cusi, D., Daly, M. J., Davis, E., de Bakker, P. I. W., Debouverie, M., D'hooghe, M. B., Dixon, K., Dobosi, R., Dubois, B., Ellinghaus, D., Elovaara, I., Esposito, F., Fontenille, C., Foote, S., Franke, A., Galimberti, D., Ghezzi, A., Glessner, J., Gomez, R., Gout, O., Graham, C., Grant, S. F. A., Guerini, F. R., Hakonarson, H., Hall, P., Hamsten, A., Hartung, H-P., Heard, R. N., Heath, S., Hobart, J., Hoshi, M., Infante-Duarte, C., Ingram, G., Ingram, W., Islam, T., Jagodic, M., Kabesch, M., Kermode, A. G., Kilpatrick, T. J., Kim, C., Klopp, N., Koivisto, K., Larsson, M., Lathrop, M., Lechner-Scott, J. S., Leone, M. A., Leppa, V., Liljedahl, U., Bomfim, I. L., Lincoln, R. R., Link, J., Liu, J., Lorentzen, A. R., Lupoli, S., Macciardi, F., Mack, T., Marriott, M., Martinelli, V., Mason, D., McCauley, J. L., Mentch, F., Mero, I-L., Mihalova, T., Montalban, X., Mottershead, J., Myhr, K-M., Naldi, P., Ollier, W., Page, A., Palotie, A., Pelletier, J., Piccio, L., Pickersgill, T., Piehl, F., Pobywajlo, S., Quach, H. L., Ramsay, P. P., Reunanen, M., Reynolds, R., Rioux, J., Rodegher, M., Roesner, S., Rubio, J. P., Rueckert, I-M., Salvetti, M., Salvi, E., Santaniello, A., Schaefer, C. A., Schreiber, S., Schulze, C., Scott, R. J., Sellebjerg, F., Selmaj, K. W., Sexton, D., Shen, L., Simms-Acuna, B., Skidmore, S., Sleiman, P. M. A., Smestad, C., Sorensen, P. S., Sondergaard, H. B., Stankovich, J., Strange, R. C., Sulonen, A-M., Sundqvist, E., Syvaenen, A-C., Taddeo, F., Taylor, B., Blackwell, J. M., Tienari, P., Bramon, E., Tourbah, A., Brown, M. A., Tronczynska, E., Casas, J. P., Tubridy, N., Corvin, A., Vickery, J., Jankowski, J., Villoslada, P., Markus, H. S., Wang, K., Mathew, C. G., Wason, J., Palmer, C. N. A., Wichmann, H-E., Plomin, R., Willoughby, E., Rautanen, A., Winkelmann, J., Wittig, M., Trembath, R. C., Yaouanq, J., Viswanathan, A. C., Zhang, H., Wood, N. W., Zuvich, R., Deloukas, P., Langford, C., Duncanson, A., Oksenberg, J. R., Pericak-Vance, M. A., Haines, J. L., Olsson, T., Hillert, J., Ivinson, A. J., De Jager, P. L., Peltonen, L., Stewart, G. J., Hafler, D. A., Hauser, S. L., McVean, G., Donnelly, P. & Compston, A., 11 Aug 2011, In: NATURE. 476, 7359, p. 214 - 219 6 p.

    Research output: Contribution to journal › Letter › peer-review

    2115 Citations (Scopus)
  • 2010

    Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Franke, A., McGovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A., Bis, J. C., Bumpstead, S., Ellinghaus, D., Festen, E. M., Georges, M., Green, T., Haritunians, T., Jostins, L., Latiano, A., & 76 othersMathew, C. G., Montgomery, G. W., Prescott, N. J., Raychaudhuri, S., Rotter, J. I., Schumm, P., Sharma, Y., Simms, L. A., Taylor, K. D., Whiteman, D., Wijmenga, C., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Buening, C., Cohen, A., Colombel, J-F., Cottone, M., Stronati, L., Denson, T., De Vos, M., D'Inca, R., Dubinsky, M., Edwards, C., Florin, T., Franchimont, D., Gearry, R., Glas, J., Van Gossum, A., Guthery, S. L., Halfvarson, J., Verspaget, H. W., Hugot, J-P., Karban, A., Laukens, D., Lawrance, I., Lemann, M., Levine, A., Libioulle, C., Louis, E., Mowat, C., Newman, W., Panes, J., Phillips, A., Proctor, D. D., Regueiro, M., Russell, R., Rutgeerts, P., Sanderson, J., Sans, M., Seibold, F., Steinhart, A. H., Stokkers, P. C. F., Torkvist, L., Kullak-Ublick, G., Wilson, D., Walters, T., Targan, S. R., Brant, S. R., Rioux, J. D., D'Amato, M., Weersma, R. K., Kugathasan, S., Griffiths, A. M., Mansfield, J. C., Vermeire, S., Duerr, R. H., Silverberg, M. S., Satsangi, J., Schreiber, S., Cho, J. H., Annese, V., Hakonarson, H., Daly, M. J. & Parkes, M., Dec 2010, In: Nature Genetics. 42, 12, p. 1118 - U121 9 p.

    Research output: Contribution to journal › Letter › peer-review

    2050 Citations (Scopus)
  • 2007

    Combined evidence from three large British association studies rejects TUCAN/CARD8 as an IBD susceptibility gene

    Fisher, S. A., Mirza, M. M., Onnie, C. M., Soars, D., Lewis, C. M., Prescott, N. J., Mathew, C. G., Sanderson, J., Forbes, A., Todhunter, C., Donaldson, P. & Mansfield, J., May 2007, In: Gastroenterology. 132, 5, p. 2078 - 2080 3 p.

    Research output: Contribution to journal › Letter › peer-review

    24 Citations (Scopus)

  • Interleukin-23R arg381 gln is associated with susceptibility to Crohn's disease but not with phenotype in an Italian population - Reply

    Tremelling, M., Lees, C., Mansfiel, J., Mathew, C., Jewell, D., Satsangi, J. & Parkes, M., Sept 2007, In: Gastroenterology. 133, 3, p. 1051 - 1052 2 p.

    Research output: Contribution to journal › Letter › peer-review

  • 2005

    A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.

    Meetei, A. R., Medhurst, A., Ling, C., Xue, Y., Singh, T. R., Bier, P., Steltenpool, J., Stone, S., Dokal, I., Mathew, C. G., Hoatlin, M., Joenje, H., de Winter, J. P. & Wang, W., Sept 2005, In: Nature Genetics. 37, 9, p. 958 - 963 6 p.

    Research output: Contribution to journal › Letter › peer-review

    361 Citations (Scopus)

  • Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease.

    van Heel, D. A., Ghosh, S., Butler, M., Lundberg, A. M. C., Ahmad, T., McGovern, D. P. B., Onnie, C., Negoro, K., Goldthorpe, S., Foxwell, B. M. J., Mathew, C. G., Forbes, A., Jewell, D. P. & Playford, R. J., 2005, In: The Lancet. 365, 9473, p. 1794 - 1796 3 p.

    Research output: Contribution to journal › Letter › peer-review

    268 Citations (Scopus)

  • No association of the NFKB1 promoter polymorphism with ulcerative colitis in a British case control cohort.

    Mirza, M. M., Fisher, S. A., Onnie, C., Sanderson, J., Forbes, A., Lewis, C. M. & Mathew, C. G., Aug 2005, In: Gut. 54, 8, p. 1205 - 1206 2 p.

    Research output: Contribution to journal › Letter › peer-review

    34 Citations (Scopus)
  • 2004

    Genetic association between EPHX1 and Crohn's disease: population stratification, genotyping error, or random chance?

    Cuthbert, A. P., Fisher, S. A., Lewis, C. M., Mathew, C. G., Sanderson, J. & Forbes, A., 2004, In: Gut. 53, 9, p. 1386 - 1386 1 p.

    Research output: Contribution to journal › Letter › peer-review

    6 Citations (Scopus)
  • 2003

    Lack of association between the C3435T MDR1 gene polymorphism and inflammatory bowel disease in two independent northern European populations

    Croucher, P. J. P., Mascheretti, S., Foelsch, U. R., Hampe, J., Schreiber, S. & Mathew, C. G., Dec 2003, In: Gastroenterology. 125, 6, p. 1919 - 1920 2 p.

    Research output: Contribution to journal › Letter › peer-review

    65 Citations (Scopus)
  • 2000

    Low prevalence of germline BRCA1 mutations in early onset breast cancer without a family history

    Ellis, D., Greenman, J., Hodgson, S., McCall, S., Lalloo, F., Cameron, J., Izatt, L., Scott, G., Jacobs, C., Watts, S., Chorley, W., Perrett, C., Macdermot, K., Mohammed, S., Evans, G. & Mathew, C. G., Oct 2000, In: Journal of Medical Genetics. 37, 10, p. 792-4 3 p.

    Research output: Contribution to journal › Letter › peer-review

    15 Citations (Scopus)
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