Search results

• 2012

  TOWARDS INDIVIDUALISED RISK PREDICTION FOR CROHN'S DISEASE

  Taylor, K. M., Prescott, N. J., Anderson, S. H., Irving, P. M., West, S. L., Crouch, D. J. M., Mathew, C. G., Sanderson, J. D. & Lewis, C. M., Jul 2012, In: Gut. 61, p. A72-A72 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Smoking 100%
  • Development 50%
  • Genotyping 50%
  • Population 50%
  • Genetics 25%
  16 Citations (Scopus)
• 2011

  AUTOPHAGY GENE POLYMORPHISMS INFLUENCE THE INTERACTION OF E COLI AND MACROPHAGES IN CROHN'S DISEASE

  Elliott, T., Prescott, N., Hudspith, B., Rayment, N., Hermon-Taylor, J., Brostoff, J., Mathew, C. & Sanderson, J. D., 2011, In: Gut. 60, p. A61 - A61

  Research output: Contribution to journal › Meeting abstract
  32 Citations (Scopus)

• Increased chromosome breakage in lymphocytes exposed to ionizing radiation can be used to distinguish FANCD1 caused by biallelic BRCA2 mutations from more common forms of Fanconi anaemia

  Holden, S., Stewart, G., Byrd, P., Turnbull, C., Kesterton, I., McDonald, F., Fulton, P., Ridout, C., Davidson, A., Bye, H., Mathew, C. G. & Taylor, A. M., 2011, In: Journal of Medical Genetics. 48, p. S18 - S18

  Research output: Contribution to journal › Meeting abstract

• Screening for rare pathogenic sequence variants in inflammatory bowel disease

  Prescott, N. J., Lehne, B., Harrison, K., Knight, J., Weale, M., Simpson, M., Green, P., Lewis, C., Hart, A., Sanderson, J., Mansfield, J., Schlitt, T. & Mathew, C., 2011, In: Gut. 60, p. A62 - A62

  Research output: Contribution to journal › Meeting abstract

  • Screening 100%
  • Inflammatory Bowel Disease 100%
  • Disease 88%
  • Gene 66%
  • Nested Gene 55%
• 2010

  An evaluation of the genetic relationship between Orofacial Granulomatosis and Crohn's Disease

  Nolan, A., Mansfield, J., Mentzer, A., Sanderson, J., Prescott, N. & Mathew, C., 2010, In: Oral Diseases. 16, 6, p. 526 - 526 1 p.

  Research output: Contribution to journal › Meeting abstract

• DEMOGRAPHIC, CLINICAL AND GENETIC FACTORS ASSOCIATED WITH DYSBIOSIS IN PATIENTS WITH ACTIVE CROHN'S DISEASE

  Benjamin, J. L., Koutsoumpas, A., Hedin, C. R. H., Ng, S. C., Prescott, N. J., Pessoa-Lopes, P., Mathew, C. G., Kamm, M. A., Hart, A. L., Sanderson, J. D., Knight, S. C., Forbes, A., Stagg, A. J., Lindsay, J. O. & Whelan, K., 2010, In: Gut. 59, p. A5 - A5

  Research output: Contribution to journal › Meeting abstract
• 2009

  A FUNCTIONAL STUDY OF THE EFFECT OF THE 14 BP INSERTION DELETION POLYMORPHISM OF THE HLA-G GENE ON RESPONSE TO IMMUNOMODULATORY THERAPY IN INFLAMMATORY BOWEL DISEASE

  Baburajan, B., Prescott, N., Hudspith, B., Ansari, A., Smith, M., Arenas-Hernandes, M., Mathew, C., Fairbanks, L., Lewis, C., Marinaki, A. & Sanderson, J., 2009, In: Gut. 58, p. A24 - A24

  Research output: Contribution to journal › Meeting abstract

• IN VITRO RESPONSES OF MACROPHAGES TO E COLI CHALLENGE IN CROHN'S DISEASE

  Hudspith, B. N., Rayment, N. B., Prescott, N. J., Dominy, K., Parkes, G. C., Petrovska, L., Brostoff, J., Mathew, C. G. & Sanderson, J. D., 2009, In: Gut. 58, p. A43 - A43

  Research output: Contribution to journal › Meeting abstract
• 2008

  A 14 bp Ins/Del polymorphism in HLA-G influences response to azathioprine in Crohn's disease but not in ulcerative colitis

  Baburajam, B., Prescott, N., Smith, M., Ansari, A., Mathew, C., Marinaki, AM. & Sanderson, JD., 2008, In: Gastroenterology. 134, p. A666 - A667

  Research output: Contribution to journal › Meeting abstract

• Association of a promoter variant and copy number polymorphisms at the IRGM locus with Crohn's disease

  Prescott, N., Fisher, S. A., Dominy, K. M., Blaszczyk, K., Redon, R., Huang, N., Onnie, C. M., Lewis, C. M., Sanderson, J., Forbes, A., Mansfield, J. C., Hurles, M. E., Roberts, R. G. & Mathew, C. G., 2008, In: Journal of Medical Genetics. 45, p. S23 - S23

  Research output: Contribution to journal › Meeting abstract

• Content-dependent slpicing of two novel 5 prime untranslated exons contributes to the complex regulation of NOD2 protein expression in intestinal inflammation.

  Rosenstiel, PC., Huse, K., Franke, A., Hampe, J., Roberts, R., Mathew, C., Platzer, M. & Schreiber, S., 2008, In: Gastroenterology. 134, 4, p. A514 - A514

  Research output: Contribution to journal › Meeting abstract

• Copy Number Variation at the Crohn's disease susceptibility locus, IRGM

  Dominy, K., Prescott, N. J., Fisher, S. A., Blaszczyk, K., Redon, R., Huang, N., Onnie, C. M., Lewis, C. M., Sanderson, J., Forbes, A., Mansfield, J. C., Hurles, M. E., Roberts, R. G. & Mathew, C. G., 2008, In: Journal of Medical Genetics. 45, p. S77 - S77

  Research output: Contribution to journal › Meeting abstract

• Further evidence for shared genetic architecture between psoriasis and Crohn's disease

  Quaranta, M., Burden, A. D., Griffiths, C. E. M., Worthington, J., Mathew, C., Barker, J. N., Capon, F. & Trembath, R. C., 2008, In: Journal of Medical Genetics. 45, p. S81 - S81

  Research output: Contribution to journal › Meeting abstract

• Searching for genotype-phenotype structure: Trying to understand Crohn's disease

  Chapman, J. M., Onnie, C., Prescott, N., Fisher, S., Lewis, C., Mathew, C., Verzilli, C. J. & Whittaker, J. C., 2008, In: Annals of Human Genetics. 72, p. 688 - 688 1 p.

  Research output: Contribution to journal › Meeting abstract

• Shared genetic determinants between psoriasis, Crohn's disease and diabetes

  Quaranta, M., Allen, M., Burden, D., Worthington, J., Griffiths, C., Mathew, C., Trembath, R., Capon, F. & Barker, J., 2008, In: Journal of Investigative Dermatology. 128, p. S124 - S124 743.

  Research output: Contribution to journal › Meeting abstract

• The Arg381gln SNP in IL 23 R does not influence response to immunomodulators in ulcerative colitis or Crohn's disease.

  Baburajan, B., Prescott, N., Tremelling, M., Cummings, F., Parkes, M., Jewell, DP., Mathew, CG., Marinaki, AM. & Sanderson, JD., 2008, In: Gastroenterology. 134, p. A666 - A666

  Research output: Contribution to journal › Meeting abstract

• The combined effect of the aicartase C347g and the aldehype oxidase A3505g SNPs predict efficacy of methotrexate therapy in inflammatory bowel disease. Gastroenterology

  Baburajan, B., Prescott, N., Arenes-Hernandez, M., Tremelling, M., Cummings, F., Larkes, M., Jewell, DP., Ansari, A., Mathew, C., Marinaki, AM. & Sanderson, JD., 2008, In: Gastroenterology. 134, p. A666 - A666

  Research output: Contribution to journal › Meeting abstract
• 2007

  Estimating risks of common complex diseases across genetic and environmental risk factors: The example of Crohn's disease

  Lewis, C. M., Mathew, C. G. & Marteau, T. M., 2007, In: Annals of Human Genetics. 71, 4, p. 553 - 553 1 p.

  Research output: Contribution to journal › Meeting abstract

• Risk estimation for common complex genetic disorders: using genetic, environmental and family history information in Crohn's disease

  Lewis, C. M., Whitwell, S. C. L., Forbes, A., Sanderson, J., Mathew, C. G. & Marteau, T. M., 2007, In: Genetic Epidemiology. 31, 6, p. 636 - 637 2 p., 109.

  Research output: Contribution to journal › Meeting abstract

• The HLA-G 14bp ins-del polymorphism influences response to methotrexate in inflammatory bowel disease.

  Baburajan, B., Prescott, N., Smith, M., Ansari, A., Arenas, M., Herrlinger, K., Cummings, F., Tremelling, M., Parkes, M., Mathew, C., Jewell, DP., Marinaki, AM. & Sanderson, JD., 2007, In: Gastroenterology. 134, 4, p. A-38 - A-38

  Research output: Contribution to journal › Meeting abstract
• 2006

  5Q31 haplotype and relapse after small bowel resection

  Todhunter, C., Barbour, J., Mohuiddin, K., Price, M., Onnie, C., Mathew, C. G. & Mansfield, J. C., 2006, In: Gut. 55, p. A82 - A82 313.

  Research output: Contribution to journal › Meeting abstract

• Association of a nonsense mutation in the TUCAN (CARD8) gene with inflammatory bowel disease

  Mirza, M. M., Fisher, S. A., Onnie, C., Sanderson, J., Forbes, A., Mansfield, J., Lewis, C. M. & Mathew, C. G., 2006, In: Gut. 55, p. A15 - A16 055.

  Research output: Contribution to journal › Meeting abstract

• Association of the MDR1 gene with inflammatory bowel disease: A case control and meta-analysis study

  Onnie, C., Fisher, S. A., Pattni, R., Sanderson, J., Forbes, A., Lewis, C. M. & Mathew, C. G., 2006, In: Gut. 55, p. A77 - A77 293.

  Research output: Contribution to journal › Meeting abstract

• Detection of muramyl dipeptide sensing pathway defects in patients with Crohn's disease

  van Heel, D. A., Hunt, K. A., Ghosh, S., King, K., Gabe, S., Mathew, C. G., Forbes, A. & Playford, R. J., 2006, In: Gut. 55, 060.

  Research output: Contribution to journal › Meeting abstract

• Detection of muramyl dipeptide sensing pathway defects in patients with Crohn's disease.

  van Heel, D. A., Hunt, K. A., Ghosh, S., King, K., Gabe, S., Mathew, C., Forbes, A. & Playford, R. J., 2006, In: Gastroenterology. 130, 4, p. A64 - A64

  Research output: Contribution to journal › Meeting abstract

• Genetic evidence for a role for gut flora in the pathogenesis of NASH in humans

  Day, C. P., Leathart, J. B., McTernan, P. G., Mathew, C. & Daly, A. K., 2006, In: Hepatology. 44, 4, p. 261A - 261A 192.

  Research output: Contribution to journal › Meeting abstract

• Histological phenotype of CARD15 genotype

  Todhunter, C., Wilkinson, L., Henry, J., Mathew, C. G., Burt, A. & Mansfield, J. C., 2006, In: Gut. 55, p. A76 - A77 292.

  Research output: Contribution to journal › Meeting abstract
• 2005

  Amplification of toll-like receptor sensitivity by muramyl dipeptide is impaired in crohn's disease associated NOD2 mutations.

  van Heel, D. A., Ghosh, S., Butler, M., Hunt, K. A., Lundberg, A., Ahmad, T., mcGovern, D. P. B., Onnie, C., Negoro, K., Goldthorpe, S., Foxwell, M. J., Mathew, C. G., Forbes, A., Jewell, D. P. & Playford, R. J., 2005, In: Gut. 54, p. A1 - A1

  Research output: Contribution to journal › Meeting abstract

  54 Citations (Scopus)

• CARD15, smoking, and time to second operation in ileal Crohn's disease.

  Barbour, J., Todhunter, C. E., Price, M., Sutherland-Craggs, A., Donaldson, P. T., Dwarakarnath, D., Cunliffe, W., Kadis, S., Onnie, C., Mathew, C. G. & Mansfield, J. C., 2005, In: Gut. 54, p. A96 - A97

  Research output: Contribution to journal › Meeting abstract

• IL-6, COL1a1, and VDR gene polymorphisms and bone mineral density in Crohn's disease.

  Todhunter, C. E., Sutherland-Craggs, A., Bartram, S., Mathew, C. G., Donaldson, P. T., Daly, A. K., Francis, R. M., Mansfield, J. C. & Thompson, N. P., 2005, In: Gut. 54, p. A98 - A98

  Research output: Contribution to journal › Meeting abstract

  34 Citations (Scopus)

• Meta-analysis of association studies confirms an association between MDR1 and ulcerative colitis.

  Fisher, S. A., Onnie, C., Lewis, C. M. & Mathew, C. G., 2005, In: Genetic Epidemiology. 29, 3, p. 248 - 248 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2004

  A study of cancer incidence in Bristish Fanconi anemia families.

  Hodgson, S. V., Easton, D. F., Ball, J., Mathew, C. G. & Tischkowitz, M. D., 2004, 54th Annual Meeting of the American Society of Human Genetics. Unknown Publisher, p. 95 - 95 1 p.

  Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract

• Blau syndrome in the differential diagnosis of juvenile sarcoidosis

  Paterson, J., Mathew, C., Southwood, T. R. & Onnie, C., 2004, In: Journal of Medical Genetics. 41, p. S50 - S50

  Research output: Contribution to journal › Meeting abstract

• Chromosomal breakage syndromes and susceptibility to cancer

  Mathew, C., 2004, In: FAMILIAL CANCER. 3, 2, p. 169 - 169 1 p.

  Research output: Contribution to journal › Meeting abstract

• Evaluation of SNPs in TNF (C-857T) and MDR1 (C3435T) as susceptibility factors for IBD.

  Croucher, P., Hampe, J., Mascheretti, S., Mathew, C. G., Foelsch, U. R. & Schreiber, S., 2004, In: Gastroenterology. 126, 4, p. A359 - A359

  Research output: Contribution to journal › Meeting abstract

• Fine mapping of the 5q31 risk haplotype in Crohn's disease

  Onnie, C. M., Fisher, S. A., Mirza, M., Forbes, A., Mansfield, J., Sanderson, J., Lewis, C. M. & Mathew, C. G., 2004, In: Gut. 53, p. A37 - A37

  Research output: Contribution to journal › Meeting abstract

• Mutation selection and evolution of the Crohn's disease susceptibility gene, CARD15

  King, K., Sheikh, M., Cuthbert, A. P., Fisher, S. A., Onnie, C. M., Mirza, M. M., Sanderson, J., Forbes, A., Mansfield, J., Lewis, C. M., Roberts, R. G. & Mathew, C. G., 2004, 54th Annual Meeting of the American Society of Human Genetics. Unknown Publisher, p. 413 - 413 1 p.

  Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract

• Should chromosome breakage studies be performed in patients with VACTERL syndrome?

  Faivre, L., Gerard, M., Le Merrer, M., Huet, F., Portno, M., Verloes, A., Joenje, H., Mathew, C. G. & Baumann, C., 2004, In: European Journal of Human Genetics. 12, p. 100 - 100 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2003

  Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia

  Tischkowitz, M. D. K. E., Ameziane, N., Waisfisz, Q., De Winter, J. P., Harris, R., Stoger, R., Hodgson, S. V., Mathew, C. G. & Joenje, H., Nov 2003, In: European Journal of Human Genetics. 11, 3, p. 83 - 83 1 p.

  Research output: Contribution to journal › Meeting abstract

  53 Citations (Scopus)

• Fanconi anaemia and breast cancer - what is the connection?

  Mathew, C., Hussain, S., Witt, E. & Ashworth, A., 2003, In: Journal of Medical Genetics. 40, p. S31 - S31

  Research output: Contribution to journal › Meeting abstract
• 2002

  Analysis of Fanconi Anemia gene inactivation in sporadic squamous cell carcinoma of the head and neck.

  Haider, B., Tischkowitz, M., Jones, J., McGurk, M., Mathew, C. G. & Hodgson, S. V., 2002, In: American Journal of Human Genetics. 71, 4, p. 234 - 234 1 p.

  Research output: Contribution to journal › Meeting abstract

• Are Fanconi Anaemia genes inactivated in sporadic acute myeloid leukemia?

  Tischkowitz, M. D., Morgan, N. V., Eddy, C., Ball, S., Langabeer, S. E., Vorechovsky, I., Stoeger, R., Grimwade, D., Mathew, C. G. & Hodgson, S. V., 2002, In: European Journal of Human Genetics. 10, p. 90 - 90 1 p.

  Research output: Contribution to journal › Meeting abstract

• Efficient candidate gene study design for association studies in complex diseases

  Fisher, S. A., Moody, A., Mathew, C. G. & Lewis, C. M., 2002, In: Genetic Epidemiology. 23, 3, p. 281 1 p.

  Research output: Contribution to journal › Meeting abstract

• Lessons from Crohn's disease genetics.

  Mathew, CG. & Lewis, CM., 2002, In: British Journal of Dermatology. 147, 5, p. 1053 1 p.

  Research output: Contribution to journal › Meeting abstract

• SNP subset selection for genetic association studies

  Byng, M. C., Whittaker, J. C., Cuthbert, A. P., Mathew, C. G. & Lewis, C. M., 2002, In: Genetic Epidemiology. 23, 3, p. 271 - 271 1 p.

  Research output: Contribution to journal › Meeting abstract

• The NOD2 genotype and the clinical course of Crohns disease.

  Hampe, J., Grebe, J., Nikolaus, S., Solberg, C., Croucher, P., Mascheretti, S., Jahnsen, J., Moum, B., Klump, B., Krawczak, M., Mathew, C., Folsch, U. R., Vatn, M. & Schreiber, S., 2002, In: Gastroenterology. 122, 4, p. A29 - A30

  Research output: Contribution to journal › Meeting abstract
• 2001

  Identification of an IBD associated haplotype on BACs A-249B10 and 504N19 on proximal chromosome 16p

  Hampe, J., Frenzel, H., Nicolas, L. J., Schudy, A., Bridger, S., Van Deventer, S. J. H., Pieter, S., Lennard-Jones, J. E., Foelsch, U. R., Mathew, C. G., Curran, M. E. & Schreiber, S., 2001, In: Gastroenterology. 120, 5, p. A37 - A37

  Research output: Contribution to journal › Meeting abstract

• Inflammatory Bowel Disease: on the importance of NOD2 and sex

  Mathew, C., Cuthbert, A., Mirza, M., Fisher, S., King, K., Forbes, A., Hampe, J., Lewis, C. & Schreiber, S., 2001, In: Journal of Medical Genetics. 38, p. S27

  Research output: Contribution to journal › Meeting abstract

• Molecular genetic analysis of Fanconi anaemia in Black South Africans.

  Krause, A., Essop, F., Wainwright, L., Poole, J. & Mathew, C., 2001, In: American Journal of Human Genetics. 69, 4, p. 588 - 588 1 p.

  Research output: Contribution to journal › Meeting abstract

• Mutation analysis of the Fanconi Anaemia group A, C, E, F and G genes in sporadic acute myeloid leukaemia

  Tischkowitz, M., Morgan, N. V., Hodgson, S. V., Eddy, C., Ball, S., Langabeer, S., Vorechovsky, I., Grimwade, D. & Mathew, C., 2001, In: Journal of Medical Genetics. 38, p. S55 - S55

  Research output: Contribution to journal › Meeting abstract