King's College London

Research portal

Professor Christos Ouzounis

  1. A global metagenomic map of urban microbiomes and antimicrobial resistance

    The International MetaSUB Consortium, 24 Jun 2021, In: Cell. 184, 13, p. 3376-3393.e17

    Research output: Contribution to journalArticlepeer-review

  2. Identification of Adverse Drug Events from Free Text Electronic Patient Records and Information in a Large Mental Health Case Register

    Iqbal, E., Mallah, R., Jackson, R. G., Ball, M., Ibrahim, Z. M., Broadbent, M., Dzahini, O., Stewart, R., Johnston, C., Dobson, R. J. B. & Ouzounis, C. A. (ed.), 14 Aug 2015, In: PL o S One . 10, 8, 14 p., e0134208.

    Research output: Contribution to journalArticlepeer-review

  3. Transcriptome classification reveals molecular subtypes in psoriasis

    Ainali, C., Valeyev, N., Perera, G., Williams, A., Gudjonsson, J. E., Ouzounis, C. A., Nestle, F. O. & Tsoka, S., 12 Sep 2012, In: BMC GENOMICS. 13, -, p. - 15 p., 472.

    Research output: Contribution to journalArticlepeer-review

  4. Copy number and loss of heterozygosity detected by SNP array of formalin-fixed tissues using whole-genome amplification

    Stokes, A., Drozdov, I., Guerra, E., Ouzounis, C. A., Warnakulasuriya, S., Gleeson, M. J., McGurk, M., Tavassoli, M. & Odell, E. W., 26 Sep 2011, In: PL o S One . 6, 9, p. e24503 e24503.

    Research output: Contribution to journalArticlepeer-review

  5. Complete genome sequence of Arthrobacter phenanthrenivorans type strain (Sphe3)

    Kallimanis, A., LaButti, K. M., Lapidus, A., Clum, A., Lykidis, A., Mavromatis, K., Pagani, I., Liolios, K., Ivanova, N., Goodwin, L., Pitluck, S., Chen, A., Palaniappan, K., Markowitz, V., Bristow, J., Velentzas, A. D., Perisynakis, A., Ouzounis, C. C., Kyrpides, N. C., Koukkou, A. I., & 1 othersDrainas, C., 2011, In: Standards In Genomic Sciences. 4, 2, p. 123 - 130 8 p.

    Research output: Contribution to journalArticlepeer-review

  6. Complete genome sequence of Mycobacterium sp strain (Spyr1) and reclassification to Mycobacterium gilvum Spyr1

    Kallimanis, A., Karabika, E., Mavromatis, K., Lapidus, A., LaButti, K. M., Liolios, K., Ivanova, N., Goodwin, L., Woyke, T., Velentzas, A. D., Perisynakis, A., Ouzounis, C. C., Kyrpides, N. C., Koukkou, A. I. & Drainas, C., 2011, In: Standards In Genomic Sciences. 5, 1, p. 144 - 153 10 p.

    Research output: Contribution to journalArticlepeer-review

  7. Protein coalitions in a core mammalian biochemical network linked by rapidly evolving proteins

    Ainali, C., Simon, M., Freilich, S., Espinosa, O., Hazelwood, L., Tsoka, S., Ouzounis, C. A. & Hancock, J. M., 2011, In: Bmc Evolutionary Biology. 11, 1, 142.

    Research output: Contribution to journalArticlepeer-review

  8. Genome-wide expression patterns in physiological cardiac hypertrophy

    Drozdov, I., Tsoka, S., Ouzounis, C. A. & Shah, A. M., 11 Oct 2010, In: BMC GENOMICS. 11, 1, 557.

    Research output: Contribution to journalArticlepeer-review

  9. Promoter Complexity and Tissue-Specific Expression of Stress Response Components in Mytilus galloprovincialis, a Sessile Marine Invertebrate Species

    Pantzartzi, C., Drosopoulou, E., Yiangou, M., Drozdov, I., Tsoka, S., Ouzounis, C. A. & Scouras, Z. G., 2010, In: PL o S Computational Biology. 6, 7, e1000847.

    Research output: Contribution to journalArticlepeer-review

  10. Tumorigenic Properties of Iron Regulatory Protein 2 (IRP2) Mediated by Its Specific 73-Amino Acids Insert

    Maffettone, C., Chen, G., Drozdov, I., Ouzounis, C. & Pantopoulos, K., 2010, In: PL o S One . 5, 4, e10163.

    Research output: Contribution to journalArticlepeer-review

  11. Maps, books and other metaphors for systems biology

    Ouzounis, C. & Maziere, P., Jul 2006, In: Biosystems. 85, 1, p. 6 - 10 5 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  12. Highly consistent patterns for inherited human diseases at the molecular level

    Lopez-Bigas, N., Blencowe, B. J. & Ouzounis, C. A., 1 Feb 2006, In: BIOINFORMATICS. 22, 3, p. 269 - 277 9 p.

    Research output: Contribution to journalArticlepeer-review

  13. Structural and functional properties of genes involved in human cancer

    Furney, S. J., Higgins, D. G., Ouzounis, C. A. & Lopez-Bigas, N., 11 Jan 2006, In: BMC GENOMICS. 7, 3.

    Research output: Contribution to journalArticlepeer-review

  14. A minimal estimate for the gene content of the last universal common ancestor - exobiology from a terrestrial perspective

    Ouzounis, C. A., Kunin, V., Darzentas, N. & Goldovsky, L., Jan 2006, In: Research in Microbiology. 157, 1, p. 57 - 68 12 p.

    Research output: Contribution to journalArticlepeer-review

  15. Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes

    Tiffin, N., Adie, E., Turner, F., Brunner, H. G., van Driel, M. A., Oti, M., Lopez-Bigas, N., Ouzounis, C., Perez-Iratxeta, C., ndrade-Navarro, M. A., Adeyemo, A., Patti, M. E., Semple, C. A. M. & Hide, W., 2006, In: Nucleic Acids Research. 34, 10, p. 3067 - 3081 15 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  16. Probabilistic annotation of protein sequences based on functional classifications

    Levy, E. D., Ouzounis, C. A., Gilks, W. R. & Audit, B., 14 Dec 2005, In: BMC Bioinformatics. 6, 302.

    Research output: Contribution to journalArticlepeer-review

  17. Sensitive detection of sequence similarity using combinatorial pattern discovery: A challenging study of two distantly related protein families

    Darzentas, N., Rigoutsos, I. & Ouzounis, C. A., 1 Dec 2005, In: Proteins. 61, 4, p. 926 - 937 12 p.

    Research output: Contribution to journalArticlepeer-review

  18. Ancestral state reconstructions for genomes

    Ouzounis, C. A., Dec 2005, In: Current Opinion in Genetics and Development. 15, 6, p. 595 - 600 6 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  19. CoGenT++: an extensive and extensible data environment for computational genomics

    Goldovsky, L., Janssen, P., Ahren, D., Audit, B., Cases, I., Darzentas, N., Enright, A. J., Lopez-Bigas, N., Peregrin-Alvarez, J. M., Smith, M., Tsoka, S., Kunin, V. & Ouzounis, C. A., Oct 2005, In: BIOINFORMATICS. 21, 19, p. 3806 - 3810 5 p.

    Research output: Contribution to journalArticlepeer-review

  20. MagicMatch - cross-referencing sequence identifiers across databases

    Smith, M., Kunin, V., Goldovsky, L., Enright, A. J. & Ouzounis, C. A., 15 Aug 2005, In: BIOINFORMATICS. 21, 16, p. 3429 - 3430 2 p.

    Research output: Contribution to journalArticlepeer-review

  21. The net of life: Reconstructing the microbial phylogenetic network

    Kunin, V., Goldovsky, L., Darzentas, N. & Ouzounis, C. A., Jul 2005, In: Genome Research. 15, 7, p. 954 - 959 6 p.

    Research output: Contribution to journalArticlepeer-review

  22. The properties of protein family space depend on experimental design

    Kunin, V., Teichmann, S. A., Huynen, M. A. & Ouzounis, C. A., 1 Jun 2005, In: BIOINFORMATICS. 21, 11, p. 2618 - 2622 5 p.

    Research output: Contribution to journalArticlepeer-review

  23. Are splicing mutations the most frequent cause of hereditary disease?

    Lopez-Bigas, N., Audit, B., Ouzounis, C., Parra, G. & Guigo, R., 28 Mar 2005, In: FEBS Letters. 579, 9, p. 1900 - 1903 4 p.

    Research output: Contribution to journalArticlepeer-review

  24. An exponential core in the heart of the yeast protein interaction network

    Pereira-Leal, J. B., Audit, B., Peregrin-Alvarez, J. M. & Ouzounis, C. A., Mar 2005, In: Molecular Biology and Evolution. 22, 3, p. 421 - 425 5 p.

    Research output: Contribution to journalArticlepeer-review

  25. Clustering the annotation space of proteins

    Kunin, V. & Ouzounis, C. A., 9 Feb 2005, In: BMC Bioinformatics. 6, 24.

    Research output: Contribution to journalArticlepeer-review

  26. Expansion of the BioCyc collection of pathway/genome databases to 160 genomes

    Karp, P. D., Ouzounis, C. A., Moore-Kochlacs, C., Goldovsky, L., Kaipa, P., Ahren, D., Tsoka, S., Darzentas, N., Kunin, V. & Lopez-Bigas, N., 2005, In: Nucleic Acids Research. 33, 19, p. 6083 - 6089 7 p.

    Research output: Contribution to journalArticlepeer-review

  27. Measuring genome conservation across taxa: divided strains and united kingdoms

    Kunin, V., Ahren, D., Goldovsky, L., Janssen, P. & Ouzounis, C. A., 2005, In: Nucleic Acids Research. 33, 2, p. 616 - 621 6 p.

    Research output: Contribution to journalArticlepeer-review

  28. Functional evolution of the yeast protein interaction network

    Kunin, V., Pereira-Leal, J. B. & Ouzounis, C. A., Jul 2004, In: Molecular Biology and Evolution. 21, 7, p. 1171 - 1176 6 p.

    Research output: Contribution to journalArticlepeer-review

  29. Detection of Functional Modules From Protein Interaction Networks

    Pereira-Leal, J. B., Enright, A. J. & Ouzounis, C. A., 1 Jan 2004, In: Proteins. 54, 1, p. 49 - 57 9 p.

    Research output: Contribution to journalArticlepeer-review

  30. Genome-wide identification of genes likely to be involved in human genetic disease

    Lopez-Bigas, N. & Ouzounis, C. A., 2004, In: Nucleic Acids Research. 32, 10, p. 3108 - 3114 7 p.

    Research output: Contribution to journalArticlepeer-review

  31. Metabolic database systems for the analysis of genome-wide function

    Tsoka, S. & Ouzounis, C. A., 30 Dec 2003, In: BIOTECHNOLOGY AND BIOENGINEERING. 84, 7, p. 750 - 755 6 p.

    Research output: Contribution to journalArticlepeer-review

  32. Genome evolution reveals biochemical networks and functional modules

    von Mering, C., Zdobnov, E. M., Tsoka, S., Ciccarelli, F., Pereira-Leal, J. B., Ouzounis, C. A. & Bork, P., 23 Dec 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 26, p. 15428 - 15433 6 p.

    Research output: Contribution to journalArticlepeer-review

  33. Early bioinformatics: the birth of a discipline - a personal view

    Ouzounis, C. A. & Valencia, A., 22 Nov 2003, In: BIOINFORMATICS. 19, 17, p. 2176 - 2190 15 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  34. From genes to genomes: Universal scale-invariant properties of microbial chromosome organisation

    Audit, B. & Ouzounis, C. A., 19 Sep 2003, In: Journal of Molecular Biology. 332, 3, p. 617 - 633 17 p.

    Research output: Contribution to journalArticlepeer-review

  35. Comparison of sequence masking algorithms and the detection of biased protein sequence regions

    Kreil, D. P. & Ouzounis, C. A., 1 Sep 2003, In: BIOINFORMATICS. 19, 13, p. 1672 - 1681 10 p.

    Research output: Contribution to journalArticlepeer-review

  36. PseuRECA: genome annotation and gene context analysis for Pseudomonas aeruginosa PAO1

    Weinel, C., Ermolaeva, M. D. & Ouzounis, C., 12 Aug 2003, In: BIOINFORMATICS. 19, 12, p. 1457 - 1460 4 p.

    Research output: Contribution to journalArticlepeer-review

  37. Protein families and TRIBES in genome sequence space

    Enright, A. J., Kunin, V. & Ouzounis, C. A., 1 Aug 2003, In: Nucleic Acids Research. 31, 15, p. 4632 - 4638 7 p.

    Research output: Contribution to journalArticlepeer-review

  38. COmplete GENome Tracking (COGENT): a flexible data environment for computational genomics

    Janssen, P., Enright, A. J., Audit, B., Cases, I., Goldovsky, L., Harte, N., Kunin, V. & Ouzounis, C. A., 22 Jul 2003, In: BIOINFORMATICS. 19, 11, p. 1451 - 1452 2 p.

    Research output: Contribution to journalArticlepeer-review

  39. Gene TRACE-reconstruction of gene content of ancestral species

    Kunin, V. & Ouzounis, C. A., 22 Jul 2003, In: BIOINFORMATICS. 19, 11, p. 1412 - 1416 5 p.

    Research output: Contribution to journalArticlepeer-review

  40. Classification schemes for protein structure and function

    Ouzounis, C. A., Coulson, R. M. R., Enright, A. J., Kunin, V. & Pereira-Leal, J. B., 1 Jul 2003, In: NATURE REVIEWS GENETICS. 4, 7, p. 508 - 519 12 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  41. The balance of driving forces during genome evolution in prokaryotes

    Kunin, V. & Ouzounis, C. A., 1 Jul 2003, In: Genome Research. 13, 7, p. 1589 - 1594 6 p.

    Research output: Contribution to journalArticlepeer-review

  42. Transcription regulation and environmental adaptation in bacteria

    Cases, I., de Lorenzo, V. & Ouzounis, C. A., 1 Jun 2003, In: Trends in Microbiology. 11, 6, p. 248 - 253 6 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  43. Mapping functional associations in the entire genome of Drosophila melanogaster using fusion analysis

    Iliopoulos, I., Enright, A. J., Poullet, P. & Ouzounis, C. A., Jun 2003, In: Comparative And Functional Genomics. 4, 3, p. 337 - 341 5 p.

    Research output: Contribution to journalArticlepeer-review

  44. Evaluation of annotation strategies using an entire genome sequence

    Iliopoulos, I., Tsoka, S., Andrade, M. A., Enright, A. J., Carroll, M., Poullet, P., Promponas, V., Liakopoulos, T., Palaios, G., Pasquier, C., Hamodrakas, S., Tamames, J., Yagnik, A. T., Tramontano, A., Devos, D., Blaschke, C., Valencia, A., Brett, D., Martin, D., Leroy, C., & 3 othersRigoutsos, I., Sander, C. & Ouzounis, C. A., 12 Apr 2003, In: BIOINFORMATICS. 19, 6, p. 717 - 726 10 p.

    Research output: Contribution to journalArticlepeer-review

  45. The phylogenetic extent of metabolic enzymes and pathways

    Peregrin-Alvarez, J. M., Tsoka, S. & Ouzounis, C. A., 1 Mar 2003, In: Genome Research. 13, 3, p. 422 - 427 6 p.

    Research output: Contribution to journalArticlepeer-review

  46. The phylogenetic diversity of eukaryotic transcription

    Coulson, R. M. R. & Ouzounis, C. A., 15 Jan 2003, In: Nucleic Acids Research. 31, 2, p. 653 - 660 8 p.

    Research output: Contribution to journalArticlepeer-review

  47. Beyond 100 genomes

    Janssen, P., Audit, B., Cases, I., Darzentas, N., Goldovsky, L., Kunin, V., Lopez-Bigas, N., Peregrin-Alvarez, J. M., Pereira-Leal, J. B., Tsoka, S. & Ouzounis, C. A., 2003, In: GENOME BIOLOGY. 4, 5, 402.

    Research output: Contribution to journalLetterpeer-review

  48. Myriads of protein families, and still counting

    Kunin, V., Cases, I., Enright, A. J., de Lorenzo, V. & Ouzounis, C. A., 2003, In: GENOME BIOLOGY. 4, 2, 401.

    Research output: Contribution to journalLetterpeer-review

  49. Modeling the percolation of annotation errors in a database of protein sequences

    Gilks, W. R., Audit, B., De Angelis, D., Tsoka, S. & Ouzounis, C. A., 1 Dec 2002, In: BIOINFORMATICS. 18, 12, p. 1641 - 1649 9 p.

    Research output: Contribution to journalArticlepeer-review

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