Clemens Kiecker

Clemens Kiecker

Dr

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Personal profile

Research interests

I am interested in the genetic network that regulates the development of the vertebrate forebrain. I am using gain- and loss-of-function approaches in chick and mouse embryos as well as in tissue culture to characterise the role of extracellular signals (such as Wnts and Sonic hedgehog) and their intracellular transducers in order to understand how they establish regional identity and how they regulate the balance between proliferation and neuronal differentiation. One of the key interests of my lab is how regional cellular competence is established in the developing brain, i.e. what makes neural progenitor cells interpret given signals differently in a context-dependent fashion. I am also interested in how boundaries are established between neighbouring cell populations once their regional identity has been set, such that cells from these different regions are prevented from intermingling.

Research interests (short)

vertebrate forebrain embryogenesis; Sonic hedgehog, Wnt signalling; organisers; competence; compartment boundaries

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Philosophy, On the role of signalling by growth factors of the TGFbeta and Wnt superfamilies during embryonic axis formation and patterning in Xenopus laevis, Heidelberg University

Award Date: 1 Jan 2001

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