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Crispin Hiley

Dr

 https://orcid.org/0000-0002-5869-0775
  • 1561
    Citations

Search results

  • 2023

    Quantifying the impact of immunotherapy on RNA dynamics in cancer

    Usaite, I., Biswas, D., Dijkstra, K., Watkins, T. B., Pich, O., Puttick, C., Angelova, M., Thakkar, K., Hiley, C., Birkbak, N., Kok, M., Zaccaria, S., Wu, Y., Litchfield, K., Swanton, C. & Kanu, N., 1 Nov 2023, In: Journal for ImmunoTherapy of Cancer. 11, 11, e007870.

    Research output: Contribution to journal › Article › peer-review

    Open Access
  • 2022

    Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

    International Immuno-Oncology Biomarker Working Group, Dec 2022, In: npj Breast Cancer. 6, 1, 16.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    100 Citations (Scopus)
  • 2021

    COVID-19 and the multidisciplinary care of patients with lung cancer: an evidence-based review and commentary

    Round, T., L’Esperance, V., Bayly, J., Brain, K., Dallas, L., Edwards, J. G., Haswell, T., Hiley, C., Lovell, N., McAdam, J., McCutchan, G., Nair, A., Newsom-Davis, T., Sage, E. K. & Navani, N., 31 Aug 2021, In: British journal of cancer. 125, 5, p. 629-640 12 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    22 Citations (Scopus)

  • Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

    PEACE Consortium, TRACERx Renal Consortium, Au, L., Hatipoglu, E., Robert de Massy, M., Litchfield, K., Beattie, G., Rowan, A., Schnidrig, D., Thompson, R., Byrne, F., Horswell, S., Fotiadis, N., Hazell, S., Nicol, D., Shepherd, S. T. C., Fendler, A., Mason, R., Del Rosario, L., Edmonds, K., & 32 othersLingard, K., Sarker, S., Mangwende, M., Carlyle, E., Attig, J., Joshi, K., Uddin, I., Becker, P. D., Sunderland, M. W., Akarca, A., Puccio, I., Yang, W. W., Lund, T., Dhillon, K., Vasquez, M. D., Parker, P., Moore, D., Hiley, C., Josephs, D., Chandra, A., Spicer, J., Rudman, S., Tutt, A., Tomlinson, I., Challacombe, B., Chowdhury, S., Harrison-Phipps, K., Hill, P., Horsfield, C., O'Brien, T., Olsburgh, J. & Polson, A., 8 Nov 2021, In: CANCER CELL. 39, 11, p. 1497-1518.e11

    Research output: Contribution to journal › Article › peer-review

    Open Access
    129 Citations (Scopus)
  • 2020

    Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials

    International Immuno-Oncology Biomarker Working Group, 1 Dec 2020, In: npj Breast Cancer. 6, 1, 15.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    15 Citations (Scopus)

  • Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

    the International Immuno-Oncology Biomarker Working Group, 1 Dec 2020, In: npj Breast Cancer. 6, 1, 17.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    117 Citations (Scopus)
  • 2019

    A clonal expression biomarker associates with lung cancer mortality

    TRACERx Consortium, Biswas, D., Birkbak, N. J., Rosenthal, R., Hiley, C. T., Lim, E. L., Papp, K., Boeing, S., Krzystanek, M., Djureinovic, D., La Fleur, L., Greco, M., Döme, B., Fillinger, J., Brunnström, H., Wu, Y., Moore, D. A., Skrzypski, M., Abbosh, C., Litchfield, K., & 16 othersAl Bakir, M., Watkins, T. B. K., Veeriah, S., Wilson, G. A., Jamal-Hanjani, M., Moldvay, J., Botling, J., Chinnaiyan, A. M., Micke, P., Hackshaw, A., Bartek, J., Csabai, I., Szallasi, Z., Herrero, J., McGranahan, N. & Swanton, C., 1 Oct 2019, In: Nature Medicine. 25, 10, p. 1540-1548 9 p.

    Research output: Contribution to journal › Article › peer-review

    75 Citations (Scopus)
  • 2018

    Is heterogeneity in stage 3 non-small cell lung cancer obscuring the potential benefits of dose-escalated concurrent chemo-radiotherapy in clinical trials?

    Hudson, A., Chan, C., Woolf, D., McWilliam, A., Hiley, C., O’Connor, J., Bayman, N., Blackhall, F. & Faivre-Finn, C., 1 Apr 2018, In: Lung Cancer. 118, p. 139-147

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    File
    11 Citations (Scopus)
    328 Downloads (Pure)
  • 2017

    Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

    McGranahan, N., Rosenthal, R., Hiley, C. T., Rowan, A. J., Watkins, T. B. K., Wilson, G. A., Birkbak, N. J., Veeriah, S., Van Loo, P., Herrero, J., Swanton, C., Jamal-Hanjani, M., Shafi, S., Czyzewska-Khan, J., Johnson, D., Laycock, J., Bosshard-Carter, L., Gorman, P., Hynds, R. E., Wilson, G., & 194 othersHorswell, S., Mitter, R., Escudero, M., Stewart, A., Rowan, A., Xu, H., Turajlic, S., Abbosh, C., Goldman, J., Stone, R. K., Denner, T., Matthews, N., Elgar, G., Ward, S., Costa, M., Begum, S., Phillimore, B., Chambers, T., Nye, E., Graca, S., Al Bakir, M., Joshi, K., Furness, A., Ben Aissa, A., Wong, Y. N. S., Georgiou, A., Quezada, S., Hartley, J. A., Lowe, H. L., Lawrence, D., Hayward, M., Panagiotopoulos, N., Kolvekar, S., Falzon, M., Borg, E., Marafioti, T., Simeon, C., Hector, G., Smith, A., Aranda, M., Novelli, M., Oukrif, D., Janes, S. M., Thakrar, R., Forster, M., Ahmad, T., Lee, S. M., Papadatos-Pastos, D., Carnell, D., Mendes, R., George, J., Navani, N., Ahmed, A., Taylor, M., Choudhary, J., Summers, Y., Califano, R., Taylor, P., Shah, R., Krysiak, P., Rammohan, K., Fontaine, E., Booton, R., Evison, M., Crosbie, P., Moss, S., Idries, F., Joseph, L., Bishop, P., Chaturved, A., Quinn, A. M., Doran, H., Leek, A., Harrison, P., Moore, K., Waddington, R., Novasio, J., Blackhall, F., Rogan, J., Smith, E., Dive, C., Tugwood, J., Brady, G., Rothwell, D. G., Chemi, F., Pierce, J., Gulati, S., Naidu, B., Langman, G., Trotter, S., Bellamy, M., Bancroft, H., Kerr, A., Kadiri, S., Webb, J., Middleton, G., Djearaman, M., Fennell, D., Shaw, J. A., Le Quesne, J., Moore, D., Nakas, A., Rathinam, S., Monteiro, W., Marshall, H., Nelson, L., Bennett, J., Riley, J., Primrose, L., Martinson, L., Anand, G., Khan, S., Amadi, A., Nicolson, M., Kerr, K., Palmer, S., Remmen, H., Miller, J., Buchan, K., Chetty, M., Gomersall, L., Lester, J., Edwards, A., Morgan, F., Adams, H., Davies, H., Kornaszewska, M., Attanoos, R., Lock, S., Verjee, A., MacKenzie, M., Wilcox, M., Bell, H., Hackshaw, A., Ngai, Y., Smith, S., Gower, N., Ottensmeier, C., Chee, S., Johnson, B., Alzetani, A., Shaw, E., Lim, E., De Sousa, P., Barbosa, M. T., Bowman, A., Jordan, S., Rice, A., Raubenheimer, H., Proli, C., Cufari, M. E., Ronquillo, J. C., Kwayie, A., Bhayani, H., Hamilton, M., Bakar, Y., Mensah, N., Ambrose, L., Devaraj, A., Buderi, S., Finch, J., Azcarate, L., Chavan, H., Green, S., Mashinga, H., Nicholson, A. G., Lau, K., Sheaff, M., Schmid, P., Conibear, J., Ezhil, V., Ismail, B., Irvin-sellers, M., Prakash, V., Russell, P., Light, T., Horey, T., Danson, S., Bury, J., Edwards, J., Hill, J., Matthews, S., Kitsanta, Y., Suvarna, K., Fisher, P., Keerio, A. D., Shackcloth, M., Gosney, J., Postmus, P., Feeney, S., Asante-Siaw, J., Aerts, H. J. W. L., Dentro, S. & Dessimoz, C., 30 Nov 2017, In: Cell. 171, 6, p. 1259-1271.e11

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    912 Citations (Scopus)
    524 Downloads (Pure)

  • Intratumoural evolutionary landscape of high-risk prostate cancer: The PROGENY study of genomic and immune parameters

    Linch, M., Goh, G., Hiley, C., Shanmugabavan, Y., McGranahan, N., Rowan, A., Wong, Y. N. S., King, H., Furness, A., Freeman, A., Linares, J., Akarca, A., Herrero, J., Rosenthal, R., Harder, N., Schmidt, G., Wilson, G. A., Birkbak, N. J., Mitter, R., Dentro, S., & 14 othersCathcart, P., Arya, M., Johnston, E., Scott, R., Hung, M., Emberton, M., Attard, G., Szallasi, Z., Punwani, S., Quezada, S. A., Marafioti, T., Gerlinger, M., Ahmed, H. U. & Swanton, C., 1 Oct 2017, In: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 28, 10, p. 2472-2480 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    File
    48 Citations (Scopus)
    543 Downloads (Pure)
  • 2016

    Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease

    Hiley, C. T., Le Quesne, J., Santis, G., Sharpe, R., de Castro, D. G., Middleton, G. & Swanton, C., 3 Sept 2016, In: Lancet. 388, 10048, p. 1002-1011 10 p.

    Research output: Contribution to journal › Review article › peer-review

    132 Citations (Scopus)
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