Bio-informatics, chemo-informatics, and molecular modelling; protein structure analysis and protein design; small angle neutron scattering, neutron reflectivity and neutron diffraction studies of drug delivery systems and bio-membranes.

Dave Barlow is a Reader in Computational & Molecular Biophysics, and is head of the Pharmaceutical Chemistry teaching section within the Department of Pharmacy at King’s. His research over recent years has been primarily concerned with structural and computational studies of drugs, and drug and gene delivery systems. These studies have included: detailed characterisation of the molecular architectures and membrane interactions of gene delivery vehicles; development of novel software for modelling biological membrane structure; development of expert systems approaches for drug discovery and modelling of drug delivery systems; and the development of novel systems for heterologous expression of eukaryotic integral membrane proteins.

Dave completed a BSc in Biochemistry at University College London in 1975, and spent the next 6 years teaching Biology and Chemistry in a secondary school in the West Midlands. In the final two years of his teaching, he attended part time at Birkbeck College in London, where he completed an MSc in Bio-molecular Organisation. He then moved down back to London, and studied full time for a PhD under the supervision of Janet Thornton in the Crystallography Department at Birkbeck College. After graduating with a PhD in 1984, Dave worked for a short while as a postdoctoral researcher for Janet Thornton, and in 1985 took up a post as New Blood Lecturer in Molecular Graphics & Drug Design in the Pharmacology and Pharmacy Departments at King’s College London. Dave has remained at King’s ever since.