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  Establishing the mode of action of disruptive antimicrobial technology on membranes of biological significance

  Barlow, D. (Primary Investigator) & Foglia, F. (Co-Investigator)

  EPSRC Engineering and Physical Sciences Research Council, Unilever UK Central Resources Ltd

  2/04/2018 → 1/04/2019

  Project: Research

  • Membrane 100%
  • Antiinfective Agent 100%

• insideVIR - In silico-assisted development of small-molecule inhibitors of virus replication

  Castagnolo, D. (Primary Investigator) & Barlow, D. (Co-Investigator)

  1/10/2016 → 30/09/2020

  Project: Research

• A mechanistic approach to predicting the long term stability of topically applied emulsions

  Lawrence, M. (Primary Investigator) & Barlow, D. (Co-Investigator)

  GSK GlaxoSmithKline Consumer Healthcare

  19/09/2016 → 18/09/2020

  Project: Research

• The role of the Alzheimer's disease risk gene PICALM in blood brain barrier transport, Alzheimer's disease and amyloid angiopathy

  Abbott, J. (Primary Investigator) & Barlow, D. (Co-Investigator)

  MRC Medical Research Council

  1/06/2016 → 31/05/2019

  Project: Research

• Repurposing of drugs for treatment of Psychiatric Conditions

  Barlow, D. (Primary Investigator), Herrero Zazo, M. (Co-Investigator) & Taylor, D. (Co-Investigator)

  University of London

  1/10/2015 → 30/09/2017

  Project: Research

• CCP-SAS: Collaborative Computational Project for advanced analyses of structural data in chemical biology and soft condensed matter

  Barlow, D. (Primary Investigator)

  1/04/2015 → 31/03/2020

  Project: Research

• SI2-CHE: CCP-SAS - Collaborative Computational Project for advanced analyses of structural data in chemical biology and soft condensed matter

  Barlow, D. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  1/08/2013 → 31/07/2017

  Project: Research

• Fundamental investigation of mitochondrial drug targeting and import

  Barlow, D. (Primary Investigator), Hider, R. (Co-Investigator) & Lorenz, C. (Co-Investigator)

  1/04/2013 → 31/03/2016

  Project: Research

• Clust-scan-metabolome: an integrated computer package to map the biochemical potential from large 'omic' datasets

  Long, P. (Primary Investigator) & Barlow, D. (Co-Investigator)

  2/03/2013 → 1/03/2018

  Project: Research

• ClustScan-metabolome: an integrated computer package to map the biochemical potential from large 'omic' datasets

  Long, P. (Primary Investigator) & Barlow, D. (Co-Investigator)

  2/01/2013 → 1/01/2018

  Project: Research

• Novel biosurfactants for pharmaceuticval and biomedical applications

  Barlow, D. (Primary Investigator)

  3/09/2012 → 2/09/2015

  Project: Research

• Novel biosurfactants from pharmaceutical formulation

  Barlow, D. (Primary Investigator)

  University of London

  1/09/2012 → 30/09/2014

  Project: Research

• Identifying amino acid residues involved in BACE1 homodimerisation

  Parsons, R. (Primary Investigator) & Barlow, D. (Co-Investigator)

  1/01/2012 → 31/12/2015

  Project: Research

• Pharmaceutical biophysics at Harwell

  Barlow, D. (Primary Investigator), Drake, A. (Co-Investigator), Dreiss, C. (Co-Investigator), Harvey, R. (Co-Investigator), Lawrence, M. (Co-Investigator), Mason, J. (Co-Investigator), McLain, S. (Co-Investigator) & Quinn, P. (Co-Investigator)

  3/01/2011 → 2/01/2016

  Project: Research

• Pharmaceutical biophysics at Harwell

  Barlow, D. (Primary Investigator), Dreiss, C. (Primary Investigator), Harvey, R. (Primary Investigator), Lawrence, M. (Primary Investigator), Mason, J. (Primary Investigator), Drake, A. (Co-Investigator), McLain, S. (Co-Investigator) & Quinn, P. (Co-Investigator)

  3/01/2011 → 2/01/2016

  Project: Research

• The Biomedical Summit series: where scientists, journalists, and new media deliverate on controversial science

  Barlow, D. (Primary Investigator), Dailey, L. A. (Primary Investigator), Lawrence, M. (Primary Investigator), Dabkowska, A. (Co-Investigator) & Patel, N. (Co-Investigator)

  1/11/2010 → 31/10/2012

  Project: Research

• Neutrons: small balls for big science

  Barlow, D. (Primary Investigator)

  4/10/2010 → 3/10/2012

  Project: Research

• Exploration of novel approaches for treatment of Parkinson's disease

  Barlow, D. (Primary Investigator) & Parsons, R. (Primary Investigator)

  1/10/2010 → 30/09/2012

  Project: Research

• Integration of polypharmacology and network biology in discovery of novel therapeutics

  Barlow, D. (Primary Investigator) & Hylands, P. (Primary Investigator)

  1/09/2009 → 31/08/2011

  Project: Research

• Molecular mechanisms of antimicrobial peptides: phase changes induced in endotoxic bacterial liopolysaccharide

  Harvey, R. (Primary Investigator), Lawrence, M. (Primary Investigator), Mason, J. (Primary Investigator) & Barlow, D. (Co-Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  1/10/2008 → 30/09/2013

  Project: Research

• Good Practice in Traditional Chinese Medicine Research in the Post-Genomic Era - GP-TCM

  Hylands, P. (Primary Investigator), Xu, Q. (Primary Investigator), Barlow, D. (Co-Investigator), Hendry, B. (Co-Investigator) & Houghton, P. (Co-Investigator)

  EC European Commission

  1/08/2008 → 30/04/2012

  Project: Research

  • Clinical Trial 100%
  • Phytotherapy 100%
  • Diseases 100%
  • Animal Medicine 100%

• Comprehensive database of traditional Chinese medicine

  Barlow, D. (Primary Investigator) & Hylands, P. (Primary Investigator)

  ICUK Innovation China UK

  1/06/2008 → 31/05/2009

  Project: Research

• Biophysical studies of model bio-membranes and investigation of the molecular mechanism of the antimycotic drug amphotericin

  Barlow, D. (Primary Investigator), Drake, A. (Co-Investigator), Heenan, R. (Co-Investigator), Lawrence, M. (Co-Investigator) & Ward, A. (Co-Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  1/10/2007 → 30/09/2011

  Project: Research

• Novel system for producing membrane proteins in bacteria

  Barlow, D. (Primary Investigator), Lawrence, M. (Primary Investigator), Harvey, R. (Co-Investigator), Marsh, P. (Co-Investigator) & Panaretou, B. (Co-Investigator)

  Heptagon Proof of Concept Fund

  1/02/2005 → 30/11/2005

  Project: Research

• Membrane Protein Expression.

  Barlow, D. (Primary Investigator), Lawrence, M. (Primary Investigator), Marsh, P. (Co-Investigator) & Panaretou, B. (Co-Investigator)

  Principal's Discretionary Fund

  1/09/2004 → 31/01/2005

  Project: Research

• Blanket agreement release

  Barlow, D. (Primary Investigator) & Lawrence, M. (Co-Investigator)

  CCLRC Council for the Central Laboratory of the Research Councils

  1/01/2003 → 11/04/2004

  Project: Research

• Vesicle Formation in Non-Aquenous Solvents

  Lawrence, M. (Primary Investigator) & Barlow, D. (Co-Investigator)

  CCLRC Council for the Central Laboratory of the Research Councils

  1/01/2003 → 11/04/2004

  Project: Research

• Interaction Of The Cationic Polymer, Chitosan With Plasmid DNA And Artificial Membranes

  Lawrence, M. (Primary Investigator) & Barlow, D. (Co-Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council

  1/10/2002 → 30/09/2004

  Project: Research

• A novel method for rapid comparison of molecular shapes.

  Barlow, D. (Primary Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council

  1/10/1999 → 30/09/2002

  Project: Research

• Novel lipid analogues for production of long-circulating vesicles

  Barlow, D. (Primary Investigator) & Lawrence, M. (Primary Investigator)

  Leverhulme Trust

  1/01/1998 → 31/12/2000

  Project: Research

• Computer simulation of polymer and surfactant aggregates and monolayers

  Barlow, D. (Primary Investigator)

  CCLRC Council for the Central Laboratory of the Research Councils

  1/10/1996 → 30/09/1999

  Project: Research