David Mountford

David Mountford

Dr

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Personal profile

Research interests

Currently specific areas of interest are in:  

  • Novel piperidine architectures.
  • Synthesis of antimalarial Natural Products.
  • Novel multi-component reactions.
  • Evaluation of possible new approaches to organocatalysis.
  • Fragment based Drug Discovery.
  • Drug targets for Asthma, inflammation and pain.

Research interests (short)

Medicinal Chemistry. Synthetic Methodology. Pain and inflamation. Angiogenesis.

Biographical details

Dr Mountford completed his PhD in synthetic Organic Chemistry at Imperial College London and carried out postdoctoral research at the Université de Montréal before returning to the UK to take up a position as a Senior Medicinal Chemist at Cambridge Biotechnology Ltd.

Since joining King’s College London in early 2009, he has divided his time between two distinct areas of research. Firstly, the development of new synthetic methods for the preparation of classes of molecule that are either poorly described in the literature or are currently not described. The rationale behind targeting these classes of compounds lies in both an ability to construct compounds to probe regions of a drug target’s active site that are currently inaccessible using the constructs currently available, and the improved IP position that would be obtained if these molecules were incorporated into a drug candidate.

The second area of research lies in the application of Drug Discovery methods to biological targets. Current targets lie in the fields of allergy, pain and inflammation, areas which Dr Mountford knows well from his time at CBT.

Current research is focused on a number of biological targets, both those that are well described in the literature and also potentially new drug targets arising from original research being carried out at King’s College London.

In addition to his research and teaching responsibilities within the School of Pharmacy, Dr Mountford is an Innovation Fellow, working with King’s College London Business Ltd. to promote the research being carried out in the Institute of Pharmaceutical Science, and to develop links between the Institute and Industry to better facilitate translation and partnering of projects. 

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