King's College London

Research portal

Mr David Richards

  1. NuSTEC White Paper: Status and Challenges of Neutrino-Nucleus Scattering

    Alvarez-Ruso, L., Athar, M. S., Barbaro, M. B., Cherdack, D., Christy, M. E., Coloma, P., Donnelly, T. W., Dytman, S., Gouvêa, A. D., Hill, R. J., Huber, P., Jachowicz, N., Katori, T., Kronfeld, A. S., Mahn, K., Martini, M., Morfín, J. G., Nieves, J., Perdue, G. N., Petti, R. & 5 others, Richards, D. G., Sánchez, F., Sato, T., Sobczyk, J. T. & Zeller, G. P., 1 May 2018, In : Progress in Particle and Nuclear Physics, Volume.

    Research output: Contribution to journalArticle

  2. Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma

    Gupta, A., Dimeloe, S., Richards, D., Chambers, E. S., Black, C., Urry, Z., Ryanna, K., Xystrakis, E., Bush, A., Saglani, S. & Hawrylowicz, C. M., Jun 2014, In : Thorax. 69, 6, p. 508-515 8 p.

    Research output: Contribution to journalArticle

  3. The effects of calcitriol treatment in glucocorticoid-resistant asthma

    Nanzer, A. M., Chambers, E. S., Ryanna, K., Freeman, A. T., Colligan, G., Richards, D., Timms, P. M., Martineau, A. R., Griffiths, C. J., Corrigan, C. J. & Hawrylowicz, C. M., Jun 2014, In : The Journal of allergy and clinical immunology. 133, 6, p. 1755-1757.e4 7 p.

    Research output: Contribution to journalArticle

  4. Depigmented-polymerised allergoids favour regulatory over effector T cells: enhancement by 1α, 25-dihydroxyvitamin D3

    Urry, Z. L., Richards, D. F., Black, C., Morales, M., Carnés, J., Hawrylowicz, C. M. & Robinson, D. S., 29 May 2014, In : BMC Immunology (Associate editor. 15, 8 p., 21.

    Research output: Contribution to journalArticle

  5. Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion

    Nanzer, A. M., Chambers, E. S., Ryanna, K., Richards, D., Black, C., Timms, P. M., Martineau, A. R., Griffiths, C. J., Corrigan, C. J. & Hawrylowicz, C. M., Aug 2013, In : Journal of Allergy and Clinical Immunology. 132, 2, p. 297-304.e3 11 p.

    Research output: Contribution to journalArticle

  6. The role of 1α,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+ and IL-10+ CD4+ T cells

    Urry, Z., Chambers, E. S., Xystrakis, E., Dimeloe, S., Richards, D. F., Gabryšová, L., Christensen, J., Gupta, A., Saglani, S., Bush, A., O'Garra, A., Brown, Z. & Hawrylowicz, C. M., Oct 2012, In : European Journal of Immunology. 42, 10, p. 2697-2708 12 p.

    Research output: Contribution to journalArticle

  7. Serum 25-dihydroxyvitamin D levels correlate with CD4(+)Foxp3(+) T-cell numbers in moderate/severe asthma

    Chambers, E. S., Nanzer, A. M., Richards, D. F., Ryanna, K., Freeman, A. T., Timms, P. M., Martineau, A. R., Griffiths, C. J., Corrigan, C. J. & Hawrylowicz, C. M., Aug 2012, In : Journal of Allergy and Clinical Immunology. 130, 2, p. 542-544 3 p.

    Research output: Contribution to journalArticle

  8. 1α,25-dihydroxyvitamin D3 promotes CD200 expression by human peripheral and airway-resident T cells

    Dimeloe, S., Richards, D., Urry, Z. L., Gupta, A., Stratigou, V., Farooque, S., Saglani, S., Bush, A. & Hawrylowicz, C. M., Jul 2012, In : Thorax. 67, 7, p. 574-581 8 p.

    Research output: Contribution to journalArticle

  9. Vitamin D binding protein and asthma severity in children

    Gupta, A., Dimeloe, S., Richards, D., Bush, A., Saglani, S. & Hawrylowicz, C. M., Jun 2012, In : Journal of Allergy and Clinical Immunology. 129, 6, p. 1669-1671 3 p.

    Research output: Contribution to journalLetter

  10. A randomized placebo-controlled trial of rush preseasonal depigmented polymerized grass pollen immunotherapy*

    Pfaar, O., Urry, Z., Robinson, D. S., Sager, A., Richards, D., Hawrylowicz, C. M., Bräutigam, M. & Klimek, L., Feb 2012, In : Allergy. 67, 2, p. 272 - 279 8 p.

    Research output: Contribution to journalArticle

  11. Relationship between Serum Vitamin D, Disease Severity, and Airway Remodeling in Children with Asthma

    Gupta, A., Sjoukes, A., Richards, D., Banya, W., Hawrylowicz, C., Bush, A. & Saglani, S., 15 Dec 2011, In : American Journal of Respiratory and Critical Care Medicine. 184, 12, p. 1342 - 1349 8 p.

    Research output: Contribution to journalArticle

  12. Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function

    Urry, Z., Xystrakis, E., Richards, D. F., McDonald, J., Sattar, Z., Cousins, D. J., Corrigan, C. J., Hickman, E., Brown, Z. & Hawrylowicz, C. M., 2 Feb 2009, In : Journal of Clinical Investigation. 119, 2, p. 387 - 398 12 p.

    Research output: Contribution to journalArticle

  13. Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients

    Xystrakis, E., Kusumakar, S., Boswell, S., Peek, E., Urry, Z., Richards, D., Adikibi, T., Pridgeon, C., Dallman, M., Loke, T-K., Robinson, D. S., Barrat, F. J., O'Garra, A., Lavender, P., Lee, T. H., Corrigan, C., Hawrylowicz, C. M. & Richards, D., 4 Jan 2006, In : Journal of Clinical Investigation. 116, 1, p. 146 - 155 10 p.

    Research output: Contribution to journalArticle

  14. Functional plasticity of human respiratory tract dendritic cells: GM-CSF enhances T(H)2 development

    Faith, A., McDonald, J., Peek, E., Richards, D., Caulfield, J., Chevretton, E., Roberts, D., Lee, T., Corrigan, C. & Hawrylowicz, C., Nov 2005, In : Journal of Allergy and Clinical Immunology. 116, 5, p. 1136 - 1143 8 p.

    Research output: Contribution to journalArticle

  15. Virtual centre for improving oral health--vC-IOH

    Clarkson, J., Pitts, N., Richards, D., Shaw, W. C., Treasure, E. T. & Worthington, H., 2004, In : Evidence-Based Dentistry. 5, 1, p. 5-6 2 p.

    Research output: Contribution to journalArticle

  16. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines

    Barrat, F. J., Cua, D. J., Boonstra, A., Richards, D. F., Crain, C., Savelkoul, H. F., de Waal-Malefyt, R., Coffman, R. L., Hawrylowicz, C. M. & O'Garra, A., 4 Mar 2002, In : Journal of Experimental Medicine. 195, 5, p. 603 - 616 14 p.

    Research output: Contribution to journalArticle

  17. Glucocorticoids drive human CD8(+) T cell differentiation towards a phenotype with high IL-10 and reduced IL-4, IL-5 and IL-13 production

    Richards, D. F., Fernandez, M., Caulfield, J., Hawrylowicz, C. M. & Richards, D., Aug 2000, In : European Journal of Immunology. 30, 8, p. 2344-54 11 p.

    Research output: Contribution to journalArticle

  18. Mycophenolic acid-induced GTP depletion also affects ATP and pyrimidine synthesis in mitogen-stimulated primary human T-lymphocytes

    Qiu, Y., Fairbanks, L. D., Rückermann, K., Hawrylowicz, C., Richards, D. F., Kirschbaum, B. & Simmonds, H. A., 15 Mar 2000, In : Transplantation. 69, 5, p. 890-897 8 p.

    Research output: Contribution to journalArticle

  19. DNase I footprinting of the human interleukin-5 gene promoter

    Cousins, D. J., Richards, D., Kemeny, D. M., Romagnani, S., Lee, T. H. & Staynov, D. Z., Jan 2000, In : Immunology. 99, 1, p. 101-108 8 p.

    Research output: Contribution to journalArticle

  20. Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: a metabolic basis for efficacy in rheumatoid arthritis?

    Fairbanks, L. D., Rückemann, K., Qiu, Y., Hawrylowicz, C. M., Richards, D. F., Swaminathan, R., Kirschbaum, B. & Simmonds, H. A., 15 Aug 1999, In : Biochemical Journal. 342 ( Pt 1), p. 143-52 10 p.

    Research output: Contribution to journalArticle

  21. Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans

    Rückemann, K., Fairbanks, L. D., Carrey, E. A., Hawrylowicz, C. M., Richards, D. F., Kirschbaum, B. & Simmonds, H. A., 21 Aug 1998, In : Journal of Biological Chemistry. 273, 34, p. 21682-91 10 p.

    Research output: Contribution to journalArticle

  22. Biochemical basis for the impaired immune response in chronic renal failure?

    Ruckemann, K., Laurence, A., Fairbanks, L. D., Richards, D., Smolenski, R. T., Hawrylowicz, C., Bofill, M. & Simmonds, H. A., 1998, In : Advances in Experimental Medicine And Biology. 431, p. 559-63 5 p.

    Research output: Contribution to journalArticle

  23. Immune memory in CD4+ CD45RA+ T cells

    Richards, D., Chapman, M. D., Sasama, J., Lee, T. H., Kemeny, D. M. & Richards, D., Jul 1997, In : Immunology. 91, 3, p. 331-9 9 p.

    Research output: Contribution to journalArticle

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