Personal profile
Biographical details
Dr. Davide Danovi is leading the Cell Phenotyping Unit at King's College London in the framework of the HipSci project, funded by the Wellcome Trust and MRC.
Prior to this, he was principal scientist at Progenitor Labs, a novel biotechnology company founded to isolate drugs for regenerative medicine using innovative stem cell technologies.
Before, he worked with Prof. Austin Smith and Dr. Steve Pollard at the University of Cambridge and at University College London where he developed a live image based chemical screening platform to isolate compounds active on human neural stem cells from normal or brain tumour samples.
He holds an MD from University of Milan and a PhD in Molecular Oncology from the European Institute of Oncology where he demonstrated the causative role of the HdmX protein in human cancer.
Education/Academic qualification
Doctor of Philosophy, European Institute of Oncology / Open University
Award Date: 1 Jan 2004
Doctor of Medicine, University of Milan
Award Date: 1 Jan 2000
Keywords
- Q Science (General)
- stem cells
- high content screening
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Cell shape characteristics of human skeletal muscle cells as a predictor of myogenic competency: A new paradigm towards precision cell therapy
Desprez, C., Danovi, D., Knowles, C. H. & Day, R. M., 1 Jan 2023, In: Journal of Tissue Engineering. 14Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Hypothesis-free phenotype prediction within a genetics-first framework
Danovi, D., 17 Feb 2023, In: Nature Communications. 14, 1, 919.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Modelling renal defects in Bardet-Biedl syndrome patients using human iPS cells
Williams, J., Hurling, C., Munir, S., Harley, P., Machado, C. B., Cujba, A.-M., Alvarez-Fallas, M., Danovi, D., Lieberam, I., Sancho, R., Beales, P. & Watt, F. M., 2023, In: Frontiers in Cell and Developmental Biology. 11, p. 1163825Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Morphogen-driven human iPSCs differentiation in 3D in vitro models of gastrulation is precluded by physical confinement: https://www.biorxiv.org/content/10.1101/2023.03.29.534685v1
Danovi, D. & Alsehli, H., 29 Mar 2023.Research output: Working paper/Preprint › Preprint
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A spatialised agent-based model of NOTCH signalling pathway in Endothelial Cells predicts emergent heterogeneity due to continual dynamic phenotypic adjustments
Engstler, E., Veschini, L., Chesnais, F., Battilocchi, M., Danovi, D., Sego, T. & Glazier, J., 2022.Research output: Working paper/Preprint › Preprint
Projects
- 6 Finished
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Glioblastoma Multiforme Patient Stratification through Novel integration of Artificial Intelligence, Big Data and Phenotypic Screening
Danovi, D. (Primary Investigator)
1/03/2021 → 31/08/2022
Project: Research
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A Proof of Concept study for the reprogramming of iPSC to manufacture cancer killing neutrophils
Danovi, D. (Primary Investigator)
1/01/2020 → 31/12/2020
Project: Research
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Use of 'Axon-like' Nanofibres to quantify and guide Glioblastoma cells migration
Danovi, D. (Primary Investigator)
1/09/2019 → 31/12/2021
Project: Research
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Using iPSC variation to define HIV-1 regulatory networks
Malim, M. (Primary Investigator), Vigilante, A. (Co-Investigator), Danovi, D. (Co-Investigator) & Apolonia, L. (Co-Investigator)
1/08/2019 → 31/07/2024
Project: Research
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Impact of missense mutations in recessive Mendelian disease: insight from ciliopathies
Danovi, D. (Primary Investigator) & Watt, F. (Co-Investigator)
1/10/2018 → 30/09/2023
Project: Research
Prizes
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Future Leader Innovation Enterprise and Research
Danovi, D. (Recipient), Jan 2020
Prize: Other distinction