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  Tissue factor pathway inhibitor C-terminal (TFPlct) reverses atherosclerosis and inhibits atherosclerotic plaque destabilization/rapture

  Chen, D. (Primary Investigator) & Dorling, A. (Co-Investigator)

  1/10/2016 → 30/09/2019

  Project: Research

• Manipulating the molecular responses of fibrocytes to prevent intimal hyperplasia.

  Dorling, A. (Primary Investigator), Chen, D. (Co-Investigator) & Lombardi, G. (Co-Investigator)

  1/01/2016 → 31/12/2018

  Project: Research

• A translational strategy to prevent and treat atherosclerosis by targeting protease-activated receptors on endothelial cells

  Dorling, A. (Primary Investigator), Chen, D. (Co-Investigator) & Smith, R. (Co-Investigator)

  1/12/2015 → 30/11/2018

  Project: Research

• Manipulating protease activated receptor (PAR) signalling on mononuclear cells to prevent intimal hyperplasia / chronic fibrosis AND promote regenerative repair

  Dorling, A. (Primary Investigator), Chen, D. (Co-Investigator), Lombardi, G. (Co-Investigator), Smith, R. (Co-Investigator) & Zhou, W. (Co-Investigator)

  1/10/2014 → 30/09/2019

  Project: Research

• Optimising Islet survival/performance by cytotopic inhibition of thrombin & protease activated receptors; a strategy for clinical translation.

  Dorling, A. (Primary Investigator), Chen, D. (Co-Investigator), Huang, G. (Co-Investigator) & Jones, P. (Co-Investigator)

  1/06/2014 → 31/05/2017

  Project: Research

• Targeting inflammatory endothelial cells with thrombin inhibitors in atherosclerosis

  Chen, D. (Primary Investigator), Dorling, A. (Co-Investigator), Sacks, S. (Co-Investigator) & Smith, R. (Co-Investigator)

  1/04/2014 → 31/03/2017

  Project: Research

• Optimising islet survival/performance by cytotopic inhibition of thrombin & protease activated receptors; a strategy for clinical translation

  Dorling, A. (Primary Investigator), Amiel, S. (Co-Investigator), Chen, D. (Co-Investigator), Huang, G. (Co-Investigator), Jones, P. (Co-Investigator), Lombardi, G. (Co-Investigator), Sacks, S. (Co-Investigator), Smith, R. (Co-Investigator) & Tree, T. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Manipulating the vascular response to injury to prevent chronic fibrosis and promote regenerative repair

  Dorling, A. (Primary Investigator), Chen, D. (Co-Investigator), Lombardi, G. (Co-Investigator), Sacks, S. (Co-Investigator), Smith, R. (Co-Investigator) & Zhou, W. (Co-Investigator)

  3/03/2013 → 2/03/2019

  Project: Research

• Preventing atherosclerosis by promoting endothelial cell regeneration through anticoagulant expression by smooth muscle progenitors

  Chen, D. (Primary Investigator), Dorling, A. (Primary Investigator) & McVey, J. (Co-Investigator)

  BHF British Heart Foundation

  1/07/2011 → 30/04/2013

  Project: Research

• Preventing atherosclerosis by promoting endothelial cell regeneration through anticoagulant expression by smooth muscle progenitors

  Chen, D. (Primary Investigator), Dorling, A. (Co-Investigator) & McVey, J. (Co-Investigator)

  1/08/2010 → 31/07/2013

  Project: Research

• Dysfunctional mobilisation of vascular progenitor cells post-kidney transplantation and post-rejection as a correlate to progressive loss of allograft function

  Chen, D. (Primary Investigator), Dorling, A. (Primary Investigator) & academic, A. (Co-Investigator)

  Guy's & St Thomas' Charity

  1/06/2010 → 31/03/2014

  Project: Research