Research output per year
Research output per year
Personal profile
Research interests
Debbie Shawcross is a Clinician Scientist and Professor of Hepatology and Chronic Liver Failure at the Roger Williams Institute of Liver Studies, King’s College London. She works as a Consultant Hepatologist on the King’s Liver Unit with a specialist interest in hepatic encephalopathy, liver failure syndromes and the complications of cirrhosis. She joined the EASL [European Association for the Study of the Liver] Scientific Committee and Governing Board in October 2022, was elected Vice Secretary General of EASL in June 2023 and took over as Secretary General in May 2025. She is an advocate for high quality education and training in gastroenterology and hepatology having been a Health Education England London Gastroenterology Training Programme Director for 10 years, British Society of Gastroenterology (BSG) Mentor and an active member of the BSG Supporting Women in Gastroenterology. She is Chair of the BSG Research Committee and in this role also serves as a Trustee of GUTS UK. She is a Clinical Advisor for The British Liver Trust and a Trustee for the European Foundation for Chronic Liver Failure.
Her research programme characterises the immunobiology of chronic liver failure focusing specifically on the gut-liver-brain axis in the context of the gut microbiome as a driver of immune dysfunction, inflammation and encephalopathy. She is leading the field in clinical trials of faecal microbiota transplantation (FMT) in Europe and is Chief Investigator of the NIHR-funded EME UK multicentre randomised placebo-controlled clinical trial of FMT (capsules) [PROMISE Trial] in patients with metabolic-associated and alcohol-related cirrhosis.
Education/Academic qualification
Doctor of Philosophy, Ammonia, infection and inflammation in hepatic encephalopathy, UCL University College London
Award Date: 1 Jan 2007
Bachelor of Medicine, Imperial College London
Award Date: 1 Jan 1996
Bachelor of Surgery, Imperial College London
Award Date: 1 Jan 1996
Bachelor of Science, Imperial College London
Award Date: 1 Jan 1993
External positions
Secretary General, EASL European Association for the Study of the Liver
9 May 2025 → …
Research Chair, British Society of Gastroenterology
23 Jun 2024 → 25 Jun 2026
Keywords
- R Medicine (General)
- Hepatology
- Acute Liver Failure
- Chronic Liver Failure
- Hepatic Encephalopathy
- Neutrophil
- Cirrhosis
- Complications of Cirrhosis
- Immunology
- Inflammation
- Alcohol
- Brain
- L Education (General)
- Gastroenterology and Hepatology
- Training Programme Director
- Phase 3 Firm Head
- Training Lead at ILS
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 7 Affordable and Clean Energy -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 10 Reduced Inequalities -
SDG 16 Peace, Justice and Strong Institutions
Fingerprint
Dive into the research topics where Debbie Shawcross is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
A global consensus on the critical care management of acute-on-chronic liver failure patients: the APASL ACLF Beijing Position Paper
APASL-ACLF Research Consortium (AARC) for APASL-ACLF working party, 30 Jul 2026, (E-pub ahead of print) In: Hepatology International.Research output: Contribution to journal › Article › peer-review
Open Access -
Ammonia measurement in cirrhosis: International Delphi consensus recommendations from ISHEN
Delphi panellists, Aug 2026, In: Journal of Hepatology. 85, 2, p. 238-256 19 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Burden and Global Distribution of Antimicrobial Resistance in Non-Bloodstream Infections Among Adults with Cirrhosis: A Systematic Review and Proportional Meta-Analysis
Ozdemir, C., Paul, T., Egoh, K., Wanford, J. J., Dekker, D., Shawcross, D. L. & Paintsil, E. K., Sept 2026, In: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 67, 9, 107849.Research output: Contribution to journal › Review article › peer-review
Open Access -
Changes in alcohol use following a diagnosis of alcohol-related liver disease: a clinical cohort study
Kann, A. E., Madsen, L. G., Rønn, J. H., Shawcross, D. L., Kalk, N., Bergmann, M. L., Jepsen, P. & Askgaard, G., Sept 2026, In: JHEP Reports. 8, 9, 101935.Research output: Contribution to journal › Article › peer-review
Open Access -
Closing the Gap: Why Liver Health Must Be Central to the United Nations Political Declaration on Non-Communicable Diseases
Krag, A., Negro, F. & Shawcross, D. L., Jan 2026, In: Journal of Hepatology. 84, 1, p. 5-9 5 p.Research output: Contribution to journal › Editorial › peer-review
6 Citations (Scopus)
-
Identifying the inflammatory and neuroinflammatory mechanisms underlying fatigue in patients with cirrhosis-associated immune dysfunction
Borsini, A. (Primary Investigator), Pariante, C. (Co-Investigator) & Shawcross, D. (Co-Investigator)
Lorna and Yuti Chernajovsky Biomedical Research Foundation
1/09/2026 → 31/08/2028
Project: Research
-
INSPIRE: Defining the INflammatory pathophySiology of dePressIon in alcohol-RElated Cirrhosis
Shawcross, D. (Primary Investigator), Borsini, A. (Co-Investigator) & Pariante, C. (Co-Investigator)
1/09/2025 → 31/08/2027
Project: Research
-
FAST Trial: Treating axial spondyloarthritis via the gut microbiome: a phase 1b clinical trial
Brown, M. (Primary Investigator), Galloway, J. (Co-Investigator), Norton, S. (Co-Investigator), Shawcross, D. (Co-Investigator) & academic, A. (Co-Investigator)
1/09/2022 → 30/05/2027
Project: Research
-
PROMISE Trial: A PROspective double-blind placebo-controlled multicentre trial of faecal MIcrobiota tranSplantation to improve outcomEs in patients with cirrhosis
Shawcross, D. (Primary Investigator), Ann Edwards, L. (Co-Investigator), Carter, B. (Co-Investigator) & academic, A. (Co-Investigator)
NIHR National Institute For Health & Care Research
1/05/2021 → 30/06/2028
Project: Research
Activities
-
Acute Alcoholic Hepatitis: The potential for immunomodulators
Shawcross, D. (Speaker)
30 Sept 2014Activity: Other › Types of External academic engagement - Invited talk
-
Chair of Workshop: Clinical Science: Targeting the gut/liver/brain axis
Shawcross, D. (Chair)
11 Sept 2014Activity: Other › Types of External academic engagement - Invited talk
-
Member of Conference Organising Committee
Shawcross, D. (Committee Member)
10 Sept 2014 → 13 Sept 2014Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
-
To Deliver a Hepatology Masterclass on Hepatic Encephalopathy
Shawcross, D. (Speaker)
16 Jun 2014Activity: Other › Types of External academic engagement - Invited talk
-
Abstract Peer Review
Shawcross, D. (Reviewer)
16 Jun 2014 → 19 Jun 2014Activity: Other › Types of External academic engagement - Membership of peer review panel or committee
Datasets
-
Supplementary material for 'The exaggerated inflammatory response to bacterial products in decompensated cirrhotic patients is orchestrated by interferons, IL-6 and IL-8' manuscript
Kronsten, V., Woodhouse, C., Zamalloa, A., Lim, T. Y., Ann Edwards, L., Martinez-Llordella, M., Sanchez-Fueyo, A. & Shawcross, D., figshare, 17 Feb 2022
DOI: 10.6084/m9.figshare.18130796
Dataset
Prizes
-
European Association for the Study of the Liver - Elected Secretary General (commences May 9th 2025 for 2-year term).
Shawcross, D. (Recipient), 9 May 2025
Prize: Election to learned society
-
Juan Rodes State of the Art Lecture in Portal Hypertension at XV Therapy in Liver Disease Meeting in Barcelona, Spain 2-4th October 2024
Shawcross, D. (Recipient), 3 Oct 2024
Prize: Prize (including medals and awards)
-