Research output per year
Research output per year
Tau, a microtubule-associated protein implicated in the development of pathology in Alzheimers disease, progressive supranuclear palsy and related tauopathies. This laboratory is particularly interested in the phosphorylation status of tau in disease and in the protein kinases involved in pathological and physiological phosphorylation of tau. Alpha-synuclein, a pre-synaptic protein present in Lewy bodies in the brain of people with Parkinsons disease, dementia with Lewy bodies, multiple system atrophy and related disorders. We are investigating biochemical modifications and functional abnormalities in disease-relevant proteins and the implications for diseases in which they play a pathological role. A wide range of techniques is used in our research, including protein chemistry, and cell and molecular biology. Table of tau phosphorylation sites compiled by Diane Hanger: https://bit.ly/2JyZTbS
Biochemistry, molecular and cell biology of proteins involved in the pathogenesis of neurodegenerative disease. Table of tau phosphorylation sites compiled by Diane Hanger: https://bit.ly/2JyZTbS
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Doctor of Philosophy, University of London
Award Date: 1 Jan 1991
Bachelor of Science, University of Leeds
Award Date: 1 Jan 1980
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
1/01/2023 → 31/12/2023
Project: Research
Bateman, J., Aarsland, D., Cash, D., Fanto, M., Giese, P., Hanger, D., Hirth, F., Malcangio, M., Miller, C., Mitchell, J., Mondal, M., Noble, W., Parsons, R., Ruepp, M., Serrano Navacerrada, M. E., So, P., Sreedharan, J., Troakes, C., Vagnoni, A., Vance, C., Vernon, A. & academic, A.
1/09/2020 → 30/09/2022
Project: Research
Noble, W., Hanger, D. & Gomez Perez-Nievas, B.
1/10/2019 → 22/03/2024
Project: Research
1/07/2019 → 1/04/2023
Project: Research