King's College London

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Dr Dickon Humphrey

  1. A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

    Solomon, D. A., Stepto, A., Au, W. H., Adachi, Y., Diaper, D. C., Hall, R., Rekhi, A., Boudi, A., Tziortzouda, P., Lee, Y. B., Smith, B., Bridi, J. C., Spinelli, G., Dearlove, J., Humphrey, D. M., Gallo, J. M., Troakes, C., Fanto, M., Soller, M., Rogelj, B. & 4 others, Parsons, R. B., Shaw, C. E., Hortobágyi, T. & Hirth, F., 1 Oct 2018, In: Brain. 141, 10, p. 2908-2924 17 p.

    Research output: Contribution to journalArticlepeer-review

  2. Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioral phenotypes that characterize ALS and FTLD

    Diaper, D. C., Adachi, Y., Lazarou, L., Greenstein, M., Simoes, F. A., Di Domenico, A., Solomon, D. A., Lowe, S., Alsubaie, R., Cheng, D., Buckley, S., Humphrey, D. M., Shaw, C. E. & Hirth, F., 1 Oct 2013, In: Human Molecular Genetics. 22, 19, p. 3883-3893 11 p.

    Research output: Contribution to journalArticlepeer-review

  3. Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes

    Diaper, D., Adachi, Y., Sutcliffe, B., Humphrey, D. M., Elliott, C. J. H., Stepto, A., Ludlow, Z. N., Vanden Broeck, L., Callaerts, P., Dermaut, B., Al-Chalabi, A., Shaw, C. E., Robinson, I. M. & Hirth, F., 15 Apr 2013, In: Human Molecular Genetics. 22, 8, p. 1539-1557 19 p.

    Research output: Contribution to journalArticlepeer-review

  4. Both loss and gain of TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration in Drosophilia

    Diaper, D. C., Adachi, Y., Sutcliffe, B., Humphrey, D. M., Elliott, C., Fielding, T., Burki, M., Ludlow, Z. N., Vanden Broeck, L., Callaerts, P., Dermaut, B., Al-Chalabi, A., Shaw, C. E. & Hirth, F., Sep 2012, In: Dementia and Geriatric Cognitive Disorders. 34, S1, p. 51-51 1 p., P10.

    Research output: Contribution to journalMeeting abstractpeer-review

  5. Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila

    Humphrey, D. M., Parsons, R. B., Ludlow, Z. N., Riemensperger, T., Esposito, G., Verstreken, P., Jacobs, H. T., Birman, S. & Hirth, F., 15 Jun 2012, In: Human Molecular Genetics. 21, 12, p. 2698-2712 15 p., dds096.

    Research output: Contribution to journalArticlepeer-review

  6. The dopaminergic system in the aging brain of Drosophila

    White, K. E., Humphrey, D. M. & Hirth, F., 8 Dec 2010, In: Frontiers in Neuroscience. 4, 205.

    Research output: Contribution to journalArticlepeer-review

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