Search results

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  Tim-3/Galectin-9 pathway in autoimmune liver disease: understanding the cause of immune-toleranc breakdown with the aim of devising a more effective form of treatment

  Longhi, S. (Primary Investigator), Ma, Y. (Co-Investigator) & Vergani, D. (Co-Investigator)

  Project: Research

• Finished

  Role of CD39 in governing the balance between regulatory and effector T helper type 17 immune responses in autoimmune sclerosing cholangitis

  Longhi, S. (Primary Investigator), Mieli-Vergani, G. (Co-Investigator) & Vergani, D. (Co-Investigator)

  1/04/2014 → 31/03/2015

  Project: Research

• Role of CD39 in governing the balance between regulatory and effector T helper type 17 immune responses in autoimmune sclerosing cholangitis

  Longhi, S. (Primary Investigator), Mieli-Vergani, G. (Co-Investigator) & Vergani, D. (Co-Investigator)

  1/04/2014 → 31/03/2015

  Project: Research

• Identification of a panel of biomarkers of predicting response to treatment in childhood autoimmune liver disease

  Ma, Y. (Primary Investigator), Heneghan, M. (Co-Investigator), Mieli-Vergani, G. (Co-Investigator), Rebollo-Mesa, I. (Co-Investigator), Thompson, R. (Co-Investigator) & Vergani, D. (Co-Investigator)

  1/04/2014 → 31/03/2016

  Project: Research

• Role of CD39 in modulating Th17 immune responses in autoimmune sclerosing cholangitis

  Longhi, S. (Primary Investigator), Mieli-Vergani, G. (Co-Investigator) & Vergani, D. (Co-Investigator)

  KHP King's Health Partners

  1/10/2013 → 30/09/2014

  Project: Research

• Identification of a panel of biomarkers for accurate diagnosis and better treatment of childhood autoimmune liver disease

  Ma, Y. (Primary Investigator), Longhi, S. (Co-Investigator), Mieli-Vergani, G. (Co-Investigator), Rebollo-Mesa, I. (Co-Investigator), Thompson, R. (Co-Investigator) & Vergani, D. (Co-Investigator)

  1/06/2013 → 31/05/2016

  Project: Research

• Role of the Galectin-9/Tim-3 pathway in the maintenance of immune-tolerance in autoimmune hepatitis

  Longhi, S. (Primary Investigator), Mieli-Vergani, G. (Co-Investigator), Rebollo-Mesa, I. (Co-Investigator) & Vergani, D. (Co-Investigator)

  1/01/2012 → 31/12/2014

  Project: Research

• Tim-3/Galectin-9 pathway in autoimmune liver disease: understanding the cause of immune-tolerance breakdown to devise a more effective form of treatment

  Longhi, S. (Primary Investigator), Mieli-Vergani, G. (Co-Investigator) & Vergani, D. (Co-Investigator)

  1/01/2012 → 31/12/2014

  Project: Research

• Sepsis and monocyte dysfunction in decompensated chronic liver disease

  Wendon, J. (Primary Investigator), Ma, Y. (Co-Investigator), Vergani, D. (Co-Investigator) & academic, A. (Co-Investigator)

  Rosetrees Trust

  1/07/2011 → 31/12/2012

  Project: Research

• Development of a novel immunological assay detecting anti-soluble liver antigen antibodies for the early diagnosis of autoimmune hepatitis

  Ma, Y. (Primary Investigator), Mieli-Vergani, G. (Primary Investigator), Vergani, D. (Primary Investigator), Bogdanos, D. (Co-Investigator), Rebollo-Mesa, I. (Co-Investigator) & Smith, R. (Co-Investigator)

  1/01/2011 → 31/03/2013

  Project: Research

• Study of phenotypic and functional stability of CD4pos and CD25pos regulatory T cells in autoimmune hepatitis

  Longhi, S. (Primary Investigator), Ma, Y. (Primary Investigator) & Vergani, D. (Primary Investigator)

  King's College Hospital Charitable Trust

  1/11/2010 → 31/10/2013

  Project: Research

• Establishment of a novel experimental model of autoimmune hepatitis

  Ma, Y. (Primary Investigator), Vergani, D. (Primary Investigator), Mieli-Vergani, G. (Co-Investigator) & Wen, L. (Co-Investigator)

  1/03/2010 → 28/02/2013

  Project: Research

• Effector and regulatory immune response in autoimmune hepatitis: the role of Tim-3-Galectin-9

  Longhi, S. (Primary Investigator), Vergani, D. (Primary Investigator) & academic, A. (Primary Investigator)

  Foundation for Science & Technology, Portugal

  1/01/2010 → 31/12/2010

  Project: Research

• Characterisation of the sequential monocyte phenotype and function during acute and chronic liver failure

  Abeles, D. (Primary Investigator), Vergani, D. (Primary Investigator) & Wendon, J. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2009 → 30/09/2012

  Project: Research

• Establishment of a novel immunological assay for the early diagnosis of autoimmune hepatitis

  Ma, Y. (Primary Investigator) & Vergani, D. (Primary Investigator)

  1/05/2009 → 30/04/2010

  Project: Research

• Establishment of a novel experimental model of autoimmune hepatitis using humanised HLA-DR3 mice

  Ma, Y. (Primary Investigator), Mieli-Vergani, G. (Primary Investigator) & Vergani, D. (Primary Investigator)

  1/01/2009 → 31/12/2011

  Project: Research

• Establishment of a novel immunological assay to distinguish patients with autoimmune hepatitis from those induced by hepatitis B virus infection

  Ma, Y. (Primary Investigator) & Vergani, D. (Co-Investigator)

  ICUK Innovation China UK

  1/01/2009 → 31/03/2009

  Project: Research

• Establishment of a novel experimental model of autoimmune hepatitis using humanised HLA-DR3 mice

  Ma, Y. (Primary Investigator), Mieli-Vergani, G. (Co-Investigator), Vergani, D. (Co-Investigator) & Wen, L. (Co-Investigator)

  1/06/2008 → 31/05/2011

  Project: Research

• Novel strategies for the generation/expansion of regulatory T-Cells to induce tolerance

  Longhi, S. (Primary Investigator), Ma, Y. (Primary Investigator), Mieli-Vergani, G. (Primary Investigator), Vergani, D. (Primary Investigator) & Gaken, J. (Co-Investigator)

  1/06/2008 → 31/05/2011

  Project: Research

• Study of PD-1/PD-L system and T-reg in health and in autoimmune hepatitis

  Ma, Y. (Primary Investigator) & Vergani, D. (Primary Investigator)

  1/04/2008 → 31/03/2010

  Project: Research

• Novel Strategies for the generation/expansion of regulatory T-Cells in the treatment of autoimmune hepatitis

  Longhi, S. (Primary Investigator) & Vergani, D. (Co-Investigator)

  1/03/2008 → 29/02/2012

  Project: Research

• Role o fHLA and Non HLA immunoregulatory genes in childhood autoimmune liver disease: a family study

  Ma, Y. (Primary Investigator), Mieli-Vergani, G. (Co-Investigator) & Vergani, D. (Co-Investigator)

  Children's Liver Disease Foundation

  1/02/2007 → 31/01/2010

  Project: Research

• Characterisation of humeral and cellular anti-nuclear Immune response in patients with autoimmune liver disease (Alex Mowat PhD Studentship)

  Vergani, D. (Primary Investigator)

  KMRT King's Medical Research Trust

  1/05/2005 → 31/05/2010

  Project: Research

• Learning of techniques enabling definition of the functional phenotype of leishmania specific T cells/clones.

  Vergani, D. (Primary Investigator) & academic, A. (Co-Investigator)

  Wellcome Trust

  1/05/2004 → 31/07/2004

  Project: Research

• Immune mechanisms of peripheral tolerance in Hepatitis B virus vertical transmission.

  Vergani, D. (Primary Investigator)

  Wellcome Trust

  1/01/2004 → 30/06/2005

  Project: Research

• Study of cytotoxic (CD8) T lymphocytes in the pathogenesis of autoimmune hepatitis type 2 and in liver-kidney microsomal antibody type 1 positive patients with chronic hepatitis C virus infection. (Alex Mowat PhD Studentship)

  Ma, Y. (Primary Investigator) & Vergani, D. (Primary Investigator)

  KMRT King's Medical Research Trust

  1/04/2003 → 31/03/2006

  Project: Research

• HLA Class II restricted T Cell immunity in AIH-2

  Mieli-Vergani, G. (Primary Investigator), Ma, Y. (Co-Investigator) & Vergani, D. (Co-Investigator)

  Children's Liver Disease Foundation

  25/02/2003 → 31/07/2005

  Project: Research

• Characterisation of soluble immune mediator patters in acute rejection and tolerance of paediatric liver transplantation

  Mieli-Vergani, G. (Primary Investigator) & Vergani, D. (Primary Investigator)

  Children Nationwide

  1/12/2002 → 30/11/2004

  Project: Research