King's College London

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Dr Eileen Gentleman

  1. Accepted/In press
  2. Accepted/In press

    Rethinking Cancer Immunotherapy by Embracing and Engineering Complexity

    Chin, M., Gentleman, E., Coppens, M-O. & Day, R., 1 May 2020, (Accepted/In press) In : TRENDS IN BIOTECHNOLOGY.

    Research output: Contribution to journalComment/debate

  3. Harnessing the secreted extracellular matrix to engineer tissues

    Blache, U., Stevens, M. M. & Gentleman, E., 1 Apr 2020, In : Nature Biomedical Engineering. 4, 4, p. 357-363 7 p.

    Research output: Contribution to journalComment/debate

  4. Hypoxia Inducible Factor-1α in osteochondral tissue engineering

    Taheem, D. K., Jell, G. & Gentleman, E. D., Apr 2020, In : Tissue Engineering Part B. 26, 2, p. 105-115 11 p.

    Research output: Contribution to journalReview article

  5. Adhesive Hydrogels for Maxillofacial Tissue Regeneration Using Minimally Invasive Procedures

    Salzlechner, C., Haghighi, T., Huebscher, I., Walther, A., Schell, S., Gardner, A., Undt, G., da Silva, R., Dreiss, C. A., Fan, K. & Gentleman, E., 19 Feb 2020, In : Advanced Healthcare Materials. 9, 4, 7 p., 1901134.

    Research output: Contribution to journalArticle

  6. Accepted/In press

    Translation Approach for Dentine Regeneration Using GSK-3 Antagonists

    Zaugg, L. K., Banu, A., Walther, A. R., Chandrasekaran, D., Babb, R. C., Salzlechner, C., Hedegaard, M. A. B., Gentleman, E. & Sharpe, P. T., 1 Jan 2020, (Accepted/In press) In : Journal of Dental Research.

    Research output: Contribution to journalArticle

  7. Multiscale analyses reveal native-like lamellar bone repair and near perfect bone-contact with porous strontium-loaded bioactive glass

    Autefage, H., Allen, F., Tang, H. M., Kallepitis, C., Gentleman, E. D., Reznikov, N., Nutiputri, K., Nommeots-Nomm, A., O'Donnell, M. D., Lange, C., Seidt, B. M., Kim, T. B., Lee, P. D., Pierce, B. F., Wagermaier, W., Fratzl, P., Goodship, A., Jones, J. R., Blunn, G. & Stevens, M., 1 Jul 2019, In : Biomaterials. 209, p. 152-162 11 p.

    Research output: Contribution to journalArticle

  8. A comparison of lithium-substituted phosphate and borate bioactive glasses for mineralised tissue repair

    Zhang, K., Alaohali, A., Sawangboon, N., Sharpe, P. T., Brauer, D. S. & Gentleman, E., 1 Jun 2019, In : Dental Materials. 35, 6, p. 919-927 9 p.

    Research output: Contribution to journalArticle

  9. An engineered, quantifiable in vitro model for analysing the effect of proteostasis-targeting drugs on tissue physical properties

    Loaiza, S., Ferreira, S. A., Chinn, T., Kirby, A., Tsolaki, E., Dondi, C., Parzych, K., Strange, A., Bozec, L., Bertazzo, S., Hedegaard, M. A. B., Gentleman, E. & Auner, H. W., Nov 2018, In : Biomaterials. 183, p. 102-113 12 p.

    Research output: Contribution to journalArticle

  10. Bi-directional cell-pericellular matrix interactions direct stem cell fate

    Ferreira, S. A., Motwani, M. S., Faull, P. A., Seymour, A. J., Yu, T., Enayati, M., Taheem, D. K., Kania, E. M., Oommen, O. P., Ahmed, T., Loaiza, S., Parzych, K., Dazzi, F. M., Auner, H. W., Varghese, O. P., Festy, F., Grigoriadis, A. E., Snijders, A. P., Bozec, L. & Gentleman, E. D., 3 Oct 2018, In : Nature Communications. 9, 1, 4049.

    Research output: Contribution to journalArticle

  11. Neighboring cells override 3D hydrogel matrix cues to drive human MSC quiescence

    Ferreira, S. A., Faull, P. A., Seymour, A. J., Yu, T. T. L., Loaiza, S., Auner, H. W., Snijders, A. P. & Gentleman, E., 1 Sep 2018, In : Biomaterials. 176, p. 13-23 11 p.

    Research output: Contribution to journalArticle

  12. Differential regulation of human bone marrow mesenchymal stromal cell chondrogenesis by Hypoxia Inducible Factor-1α hydroxylase inhibitors

    Taheem, D. K., Foyt, D., Loaiza, S., Ferreira, S. A., Ilic, D., Auner, H. W., Grigoriadis, A. E., Jell, G. & Gentleman, E. D., Sep 2018, In : Stem Cells. 36, 9, p. 1380-1392 13 p.

    Research output: Contribution to journalArticle

  13. Collective Cell Behavior in Mechanosensing of Substrate Thickness

    Tusan, C., Man, Y-H., Zarkoob, H., Johnston, D., Andriotis, O., Thurner, P., Yang, S., Sander, E., Sengers, B. G., Evans, N. & Gentleman, E. D., Jun 2018, In : Biophysical Journal. 114, 11, p. 2743-2755 13 p.

    Research output: Contribution to journalArticle

  14. Monomeric, porous type II collagen scaffolds promote chondrogenic differentiation of human bone marrow mesenchymal stem cells in vitro

    Tamaddon, M., Burrows, M., Ferreira, S. A., Dazzi, F., Apperley, J. F., Bradshaw, A., Brand, D. D., Czernuszka, J. & Gentleman, E., 3 Mar 2017, In : Scientific Reports. 7, 43519.

    Research output: Contribution to journalArticle

  15. Optimisation of lithium-substituted bioactive glasses to tailor cell response for hard tissue repair

    da Silva, J. G., Babb, R., Salzlechner, C., Sharpe, P., Brauer, D. S. & Gentleman, E., 9 Feb 2017, In : JOURNAL OF MATERIALS SCIENCE. p. 8832–8844 13 p.

    Research output: Contribution to journalArticle

  16. Aortic valve calcification: a bone of contention

    Bertazzo, S. & Gentleman, E., 2017, In : European Heart Journal. 38, 16, p. 1189-1193

    Research output: Contribution to journalArticle

  17. Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97

    Parzych, K., Chinn, T. M., Chen, Z., Loaiza, S., Porsch, F., Valbuena, G. N., Kleijnen, M. F., Karadimitris, A., Gentleman, E., Keun, H. C. & Auner, H. W., 31 Dec 2015, In : Cell Death & Disease. 6, 11 p., 2031.

    Research output: Contribution to journalArticle

  18. Composition of Mineral Produced by Dental Mesenchymal Stem Cell

    Angelova Volponi, A., Gentleman, E., Fatscher, R., Pang, Y. W. Y., Gentleman, M. M. & Sharpe, P. T., Nov 2015, In : J Dent Res. 94, 11, p. 1568-1574 7 p.

    Research output: Contribution to journalArticle

  19. Perivascular stem cells at the tip of incisors regulate tissue generation

    Pang, Y. W. Y., Feng, J., Daltoe, F., Fatscher, R., Gentleman, E. D., Gentleman, M. M. & Sharpe, P. T., 21 Oct 2015, In : Journal of Bone and Mineral Research.

    Research output: Contribution to journalArticle

  20. Therapeutic ion-releasing bioactive glass ionomer cements with improved mechanical strength and radiopacity

    Fuchs, M., Gentleman, E., Shahid, S., Hill, R. G. & Brauer, D. S., 14 Oct 2015, In : Frontiers in Materials. 2, 63.

    Research output: Contribution to journalArticle

  21. Sparse feature selection methods identify unexpected global cellular response to strontium-containing materials

    Autefage, H., Gentleman, E., Littmann, E., Hedegaard, M. A. B., Von Erlach, T., O'Donnell, M., Burden, F. R., Winkler, D. A. & Stevens, M. M., 7 Apr 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 14, p. 4280-4285 6 p.

    Research output: Contribution to journalArticle

  22. The role of surface free energy in osteoblast-biomaterial interactions

    Gentleman, M. M. & Gentleman, E., 1 Nov 2014, In : INTERNATIONAL MATERIALS REVIEWS. 59, 8, p. 417-429 13 p.

    Research output: Contribution to journalArticle

  23. The role of material structure and mechanical properties in cell-matrix interactions

    Evans, N. D. & Gentleman, E., 7 May 2014, In : Journal of materials chemistry b. 2, 17, p. 2345-2356 12 p.

    Research output: Contribution to journalArticle

  24. Surface properties and ion release from fluoride-containing bioactive glasses promote osteoblast differentiation and mineralization in vitro

    Gentleman, E., Stevens, M. M., Hill, R. G. & Brauer, D. S., Mar 2013, In : Acta Biomaterialia. 9, 3, p. 5771-5779 9 p.

    Research output: Contribution to journalArticle

  25. Nano-analytical electron microscopy reveals fundamental insights into human cardiovascular tissue calcification

    Bertazzo, S., Gentleman, E., Cloyd, K., Chester, A., Yacoub, M. & Stevens, M., 2013, In : NATURE MATERIALS.

    Research output: Contribution to journalArticle

  26. Characterization of Porcine Aortic Valvular Interstitial Cell 'Calcified' Nodules

    Cloyd, K. L., El-Hamamsy, I., Boonrungsiman, S., Hedegaard, M., Gentleman, E., Sarathchandra, P., Colazzo, F., Gentleman, M. M., Yacoub, M. H., Chester, A. H. & Stevens, M. M., 26 Oct 2012, In : PLoS ONE. 7, 10, p. - 9 p., e48154.

    Research output: Contribution to journalArticle

  27. Gene-expression Analysis Reveals that Embryonic Stem Cells Cultured Under Osteogenic Conditions Produce Mineral Non-specifically Compared to Marrow Stromal Cells or Osteoblasts

    Evans, N. D., Swain, R. J., Gentleman, E., Gentleman, M. M. & Stevens, M. M., 24 Sep 2012, In : Journal of European Cells and Materials. 24, 2012, p. 211-223 13 p.

    Research output: Contribution to journalArticle

  28. The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation

    Boonrungsiman, S., Gentleman, E., Carzaniga, R., Evans, N. D., McComb, D. W., Porter, A. E. & Stevens, M. M., 28 Aug 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 35, p. 14170-14175 6 p.

    Research output: Contribution to journalArticle

  29. Anisotropic Fibrous Scaffolds for Articular Cartilage Regeneration

    McCullen, S., Autefage, H., Callanan, A., Gentleman, E. & Stevens, M., 2012, In : Tissue Engineering Part A. 18, 19-20, p. 2073-2083 11 p.

    Research output: Contribution to journalArticle

  30. The Benefits and Drawbacks of Zinc in Glass Ionomer Bone Cements

    Brauer, D., Gentleman, E., Farrar, D., Stevens, M. & Hill, R., 2011, In : Biomedical Materials. 6, 4, 045007.

    Research output: Contribution to journalArticle

  31. Materials characterisation and cytotoxic assessment of strontium-substituted bioactive glasses for bone regeneration

    O’donnell, M. D., Candarlioglu, P. L., Miller, C. A., Gentleman, E. & Stevens, M. M., 10 Aug 2010, In : JOURNAL OF MATERIALS CHEMISTRY. 20, 40, p. 8934-8941 8 p.

    Research output: Contribution to journalArticle

  32. Conference scene: Challenges to commercialization

    Ilic, D. & Gentleman, E., May 2010, In : Regenerative Medicine. 5, 3, p. 341-343 3 p., N/A.

    Research output: Contribution to journalArticle

  33. The Effects of Strontium-Substituted Bioactive Glasses on Osteoblasts and Osteoclasts in vitro

    Gentleman, E., Fredholm, YC., Jell, G., O'Donnell, MD., Lotfibakhshaiesch, N., Hill, RG. & Stevens, MM., May 2010, In : Biomaterials. 31, 14, p. 3949 - 3956 8 p.

    Research output: Contribution to journalArticle

  34. Extracellular Matrix Mediated Osteogenic Differentiation of Murine Embryonic Stem Cells.

    Evans, ND., Gentleman, E., Polak, JM. & Stevens, MM., Apr 2010, In : Biomaterials. 31, 12, p. 3244 - 52 9 p.

    Research output: Contribution to journalArticle

  35. Comparative Materials Differences Revealed in Engineered Bone as a Function of Cell-Specific Differentiation

    Gentleman, E., Swain, RJ., Evans, ND., Boonrungsiman, S., Jell, G., Ball, MD., Shean, TAV., Oyen, ML., Porter, A. & Stevens, MM., Sep 2009, In : NATURE MATERIALS. 8, 9, p. 763 - 770 8 p.

    Research output: Contribution to journalArticle

  36. Substrate Stiffness Affects Early Differentiation Events in Embryonic Stem Cells

    Evans, ND., Minelli, C., Gentleman, E., LaPointe, V., Patankar, SN., Kallivretaki, M., Chen, X., Roberts, CJ. & Stevens, MM., Jul 2009, In : Journal of European Cells and Materials. 18, p. 1 - 14 14 p.

    Research output: Contribution to journalArticle

  37. Scaffolds for stem cells

    Evans, N. D., Gentleman, E. & Polak, J. M., Dec 2006, In : Materials Today. 9, 12, p. 26-33 8 p.

    Research output: Contribution to journalLiterature review

  38. Collagen Composite Biomaterials Resist Contraction While Allowing Development of Adipocytic Soft Tissue In Vitro

    Gentleman, E., Nauman, E., Livesay, G. & Dee, K. C., 17 Jul 2006, In : TISSUE ENGINEERING. 12, 6, p. 1639-1649 11 p.

    Research output: Contribution to journalArticle

  39. Development of Ligament-Like Structural Organization and Properties in Cell-Seeded Collagen Scaffolds in vitro

    Gentleman, E., Dee, K. C., Livesay, G. & Nauman, E., 2006, In : Annals of Biomedical Engineering. 34, 5, p. 726-736 11 p.

    Research output: Contribution to journalArticle

  40. Short Collagen Fibers Provide Control of Contraction and Permeability in Fibroblast-Seeded Collagen Gels

    Gentleman, E., Nauman, E., Dee, K. C. & Livesay, G., 9 Jul 2004, In : TISSUE ENGINEERING. 10, 3-4, p. 421-427 7 p.

    Research output: Contribution to journalArticle

  41. Mechanical Characterization of Collagen Fibers and Scaffolds for Tissue Engineering

    Gentleman, E., Lay, A., Dickerson, D., Nauman, E., Livesay, G. & Dee, K. C., Sep 2003, In : Biomaterials. 24, 21, p. 3805-3813 9 p.

    Research output: Contribution to journalArticle

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