Search results

• 2010

  New regulators of the BRCA1 response to genotoxic stress

  Morris, J. R., Boutell, C., Keppler, M., Densham, R., Weekes, D., Alamshah, A., Butler, L., Galanty, Y., Pangon, L., Kiuchi, T., Ng, T. & Solomon, E., 2010, In: Breast Cancer Research. 12, p. S2 - S2 O3.

  Research output: Contribution to journal › Meeting abstract
• 2009

  Defining the landscape of resistance mutations in the context of modern treatment protocols for acute promyelocytic leukaemia

  Jovanovic, J. V., Guidez, F., Ravandi, F., Duprez, E., Patel, M., Mills, K., Aldouri, M., Auger, M., Burnett, A. K., Solomon, E. & Grimwade, D., 2009, In: British Journal of Haematology. 145, p. 41 - 41 1 p.

  Research output: Contribution to journal › Meeting abstract
  5 Citations (Scopus)

• Genomic breakpoint cloning and a functional assay of DNA topoisomerase II cleavage reveals translocation mechanism underlying formation of t(15;17) in epirubicin-related acute promyelocytic leukaemia

  Mays, A. N., Osheroff, N., Felix, C. A., Byl, J. A., Saravanamuttu, K., Peniket, A., Corser, R., Chang, C., Hoyle, C., Parker, A. N., Hasan, S. K., Lo-Coco, F., Solomon, E. & Grimwade, D., 2009, In: British Journal of Haematology. 145, p. 43 - 43 1 p.

  Research output: Contribution to journal › Meeting abstract

• Molecular mechanisms underlying formation of balanced chromosomal rearrangements in therapy-related acute myeloid leukaemia

  Grimwade, D., Mays, A., Hasan, S. K., Mistry, A. R., Stephen, C., Satchi, G., Lennard, A., Libura, M., Byl, J. A., Osheroff, N., Solomon, E., Felix, C. & Lo-Coco, F., 2009, In: Mutagenesis. 24, 1, p. 99 - 99 1 p.

  Research output: Contribution to journal › Meeting abstract

• Molecular pathogenesis and biology of secondary leukaemias

  Grimwade, D., Mays, A. N., Osheroff, N., Byl, J. A., Hasan, S. K., Joannides, M., Solomon, E., Lo-Coco, F. & Felix, C. A., 2009, In: European Journal of Cancer Supplement. 7, 2, p. 12 - 13 2 p.

  Research output: Contribution to journal › Meeting abstract

• Role of Nbr1 in bone remodeling

  Whitehouse, C. A., Waters, S., Grigoriadis, A. E., Marchbank, K., McGowan, N., Skerry, T., Sharpe, P. T. & Solomon, E., 2009, In: Bone. 44, 2, p. S296 - S296

  Research output: Contribution to journal › Meeting abstract

• Role of Nbr1 in bone remodeling

  Marchbank, K. E., Whitehouse, C. A. & Solomon, E., 2009, In: Bone. 44, 2, p. S307 - S308

  Research output: Contribution to journal › Meeting abstract
• 2008

  Defining the Landscape of Resistance Mutations in the Context of Modern Treatment Protocols for Acute Promyelocytic Leukemia (APL)

  Jovanovic, J. V., Guidez, F., Ravandi, F., Duprez, E., Patel, M., Mills, K., Kornblau, S., Aldouri, M., Auger, M., Burnett, A. K., Solomon, E. & Grimwade, D., 2008, In: Blood. 112, 11, p. 530 - 531 2 p.

  Research output: Contribution to journal › Meeting abstract

• Evaluation of prospective real-time quantitative PCR monitoring for minimal residual disease to predict relapse and direct molecularly targeted therapy with arsenic trioxide in acute promyelocytic leukaemia: analysis of 407 patients, including results of the MRC AML15 trial

  Grimwade, D., Jovanovic, J. V., Hills, R. K., Nugent, E. A., Patel, Y., Flora, R., Diverio, D., Jones, K., Aslett, H., Batson, E., Clark, R. E., Solomon, E., Lo Coco, F., Wheatley, K. & Burnett, A. K., 2008, In: British Journal of Haematology. 141, p. 162 1 p.

  Research output: Contribution to journal › Meeting abstract

• Molecular Characterization of the t(15;17)(q22;21) in Epirubicin-Related Acute Promyelocytic Leukaemia

  Mays, A. N., Osheroff, N., Felix, C., Byl, J. A., Saravanamuttu, K., Peniket, A., Corser, R., Chang, C., Hoyle, C., Parker, A. N., Hasan, S. K., Lo-Coco, F., Solomon, E. & Grimwade, D., 2008, In: Blood. 112, 11, p. 294 - 294 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2007

  Use of quantitative PCR approaches to predict relapse and direct molecularly targeted therapy with arsenic trioxide (ATO) in acute promyelocytic leukaemia (APL)

  Grimwade, D., Jovanovic, J. V., Diverio, D., Nugent, E., Ho, A. Y., Mufti, G. J., Harrison, P., Neilson, J., Solomon, E., Hills, R. K., Clark, R. E., Lo Coco, F. & Burnett, A. K., 2007, In: British Journal of Haematology. 137, p. 39 - 39 1 p., 116.

  Research output: Contribution to journal › Meeting abstract
• 2006

  Real-time detection of PML-RARA and RARA-PML fusion transcripts in high risk acute promyelocytic leukemia (APL) treated with arsenic trioxide (ATO): Implications for realization of pre-emptive therapy for molecular relapse

  Grimwade, D., Jovanovic, J., Diverio, D., Nugent, E., Ho, A. Y., Mufti, G. J., Hills, R. K., Solomon, E., Clark, R. E., Lo Coco, F. & Burnett, A. K., 2006, In: Blood. 108, 11, p. 493 - 493 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2005

  Chromosome radiosensitivity and apoptosis in breast cancer susceptibility.

  Barwell, J. G., Georgiou, A., Pangon, L., Kesterton, I., Gilchrist, R., Ball, J., Langman, C., T. Carrier clinic collaborators, Morris, J., Wilkinson, L., Hamed, H., Solomon, E., Docherty, Z., Berg, J., Camplejohn, R., Eeles, R. & Hodgson, S., 2005, In: European Journal of Human Genetics. 13, p. 78 - 78 1 p.

  Research output: Contribution to journal › Meeting abstract

• Radiosensitivity in breast cancer susceptibility.

  Barwell, J., Georgiou, A., Kesterton, I., Pangon, L., Langman, C., Berg, J., Kote-Jarai, Z., Green, P., Sodha, N., Morris, J., Solomon, E., Docherty, Z., Camplejohn, R., Eeles, R. & Hodgson, S., 2005, In: Journal of Medical Genetics. 42, p. S21 - S21

  Research output: Contribution to journal › Meeting abstract

• Sensitive detection of FIP1L1-PDGFRA fusion transcripts by real-time quantitative RT-PCR (RQ-PCR) reveals achievement of molecular remission in chronic eosinophilic leukemia treated with low-dose Imatinib therapy.

  Jovanovic, J., Reiter, A., Cilloni, D., Gottardi, E., Score, J., Popp, H., Metzgeroth, G., Walz, C., Hochhaus, A., Roche, C., Preudhomme, C., Rondoni, M., Ottaviani, E., Rancati, F., Solomon, E., Apperley, J., Martinelli, G., Saglio, G., Hehlmann, R., Cross, N. C. P., & 1 othersGrimwade, D., 2005, In: Blood. 106, 11, p. 145a - 145a 483.

  Research output: Contribution to journal › Meeting abstract
• 2004

  BRCA1 and BRCA2: breaking the cycle and repairing the damage

  Barwell, J., Georgiou, A., Pangon, L., Kesterton, I., Gilchrist, R., Ball, J., Arden-Jones, A., Hamed, H., Wilkinson, L., Solomon, E., Camplejohn, R., Docherty, Z., Berg, J., Eeles, R. & Hodgson, S., 2004, In: Journal of Medical Genetics. 41, p. S67 - S67

  Research output: Contribution to journal › Meeting abstract

• BRCA1 and BRCA2: breaking the cycle and repairing the damage

  Barwell, J., Georgiou, A., Pangon, L., Kesterton, I., Gilchrist, R., Ball, J., Shanley, S., Ardern-Jones, A., Bishop, K., Morris, J., Wilkinson, L., Hamed, H., Camplejohn, R., Docherty, Z., Solomon, E., Berg, J., Eeles, R. & Hodgson, S., 2004, In: FAMILIAL CANCER. 3, 2, p. 149 - 149 1 p.

  Research output: Contribution to journal › Meeting abstract

• BRCA 1 and BRCA 2: Breaking the cycle and repairing the damage

  Barwell, J., Kesterton, I., Pangon, L., Georgiou, A., Gilchrist, R., Ball, J., Arden-Jones, A., Bishop, K., Locke, I., Shanley, S., Houlston, R., Chapman, C., Brewer, C., Brady, A., Dorkings, H., Homfray, T., Morris, J., Hamed, H., Wilkinson, L., Solomon, E., & 5 othersDocherty, Z., Camplejohn, R., Berg, J., Eeles, R. & Hodgson, S., 2004, In: European Journal of Human Genetics. 12, p. 178 - 178 1 p.

  Research output: Contribution to journal › Meeting abstract

• Comparison of chromosomal radiosensitivity in breast cancer patients and matched controls, using the G2 assay.

  Georgiou, A. L., Kesterton, I., Barwell, J., Pangon, L., Ball, J., Gilchrist, R., Camplejohn, R., Solomon, E., Berg, J., Hodgson, S. & Docherty, Z., 2004, 54th Annual Meeting of the American Society of Human Genetics. Unknown Publisher, p. 94 - 94 1 p.

  Research output: Chapter in Book/Report/Conference proceeding › Meeting abstract

• Genomic breakpoint cloning and a functional assay of DNA topoisomerase II cleavage reveal translocation mechanism underlying formation of t(15;17) in therapy-related acute promyelocytic leukaemia

  Mistry, A. R., Felix, C. A., Whitmarsh, R., Mason, A., Reiter, A., Cassinat, B., Parry, A., Walz, C., Wiemels, J. L., Segal, M., Ades, L., Blair, I. A., Osheroff, N., Littlewood, T. J., Lafage-Pochitaloff, M., Cross, N. C. P., Chomienne, C., Solomon, E., Fenaux, P. & Grimwade, D., 2004, In: British Journal of Haematology. 125, p. 67 - 67 1 p.

  Research output: Contribution to journal › Meeting abstract

• Nbr1 mutant mice exhibit age dependent increases in bone volume and mass

  Whitehouse, C., Horner, A., Stewart, A., Cobourne, M., McGowan, N., Burford, J., Grigoriadis, A., Sharpe, P., Skerry, T. & Solomon, E., 2004, In: Bone. 34, p. S15 - S16

  Research output: Contribution to journal › Meeting abstract

• The relationship between FLT3 mutation status, biological characteristics and outcome in patients with acute promyelocytic leukaemia

  NCRI Adult Leukaemia Working Party, Gale, R., Hills, R., Kottaridis, P., Swirsky, D., Gilkes, A., Nugent, E., Mills, K., Wheatley, K., Solomon, E., Burnett, A. K. & Linch, D. C., 2004, In: British Journal of Haematology. 125, p. 69 - 69 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2003

  BRCA1 co localises with members of the ubiquitin cascade and can regulate conjunction of ubiquitin in cells

  Morris, J. & Solomon, E., 2003, In: FAMILIAL CANCER. 2, 3-4, p. 182 - 183 2 p.

  Research output: Contribution to journal › Meeting abstract

• Mitoxantrone induces DNA topoisomerase II cleavage at translocation breakpoint hotspot in PML gene in acute promyelocytic leukemia.

  Mistry, A. R., Felix, C. A., Whitmarsh, R., Mason, A., Reiter, A., Cassinat, B., Parry, A., Walz, C., Ades, L., Blair, I. A., Osheroff, N., Littlewood, T. J., Lafage-Pochitaloff, M., Cross, N. C. P., Chomienne, C., Solomon, E., Fenaux, P. & Grimwade, D., 2003, In: Blood. 102, 11, p. 215A - 215A

  Research output: Contribution to journal › Meeting abstract

• The relationship between FLT3 mutation status: biological characteristics and outcome in patients with acute promyelocytic leukaemia.

  Grimwade, D., Gale, R., Hills, R., Kottaridis, P., Swirsky, D., Gilkes, A., Nugent, E., Mills, K., Wheatley, K., Solomon, E., Burnett, A. & Linch, D., 2003, In: Blood. 102, 11, p. 98A

  Research output: Contribution to journal › Meeting abstract

• Update on sib pair genome scan.

  Solomon, E., Hopkins, J. & Lewis, C., 2003, In: FAMILIAL CANCER. 2, 3-4, p. 183 - 183 1 p.

  Research output: Contribution to journal › Meeting abstract
• 2001

  ATM in a breast cancer series

  Izatt, L., Hodgson, S. & Solomon, E., 2001, In: FAMILIAL CANCER. 1, 3/4, p. 226 - 226 1 p.

  Research output: Contribution to journal › Meeting abstract

• Rexinoid therapy bypasses the differentiation block associated with acute promyelocytic leukemia harboring the PLZF/RAR alpha rearrangement.

  Guidez, F., Altucci, L., Xu, K., Rossin, A., Wilhelm, E., Culligan, D. J., Solomon, E., Gronemeyer, H., Zelent, A. & Grimwade, D., 2001, In: Blood. 98, 11, p. 766A - 767A

  Research output: Contribution to journal › Meeting abstract
• 1999

  Detection of minimal residual disease (MRD) in APL by "real-time" RT-PCR: Analysis of cases entered into the UK MRC ATRA trial.

  Grimwade, D., Diverio, D., Harrison, G., Wheatley, A. K., Rodgers, J., Lo Coco, F., Goldstone, A. H., Solomon, E. & Burnett, A. K., 1999, In: Blood. 94, 10, p. 625A - 625A

  Research output: Contribution to journal › Meeting abstract

• Regulation of CD2 expression in acute promyelocytic leukemia (APL).

  Grimwade, D., Craddock, C. F., Outram, S. V., Morilla, R. & Solomon, E., 1999, In: Blood. 94, 10, p. 76A - 76A

  Research output: Contribution to journal › Meeting abstract