Search results

• 2025

  A phase 1b clinical trial to determine the safety, tolerability and immunogenicity of simian adenovirus and poxvirus vectored vaccines against Mycobacterium avium complex subspecies in patients with active Crohn's disease

  Sanderson, J., Aboagye, J., Makinson, R., Rapi, K., Provstgaard-Morys, S., Stockdale, L., Alison Lawrie, L., Lanigan, I., Halim, N., Douiri, A., Greenlay, E., Malek, R., Gray, E., West, L., El Oulidi, F., Cross, P. I., Stallibrass, M., Gilbert, S. C., Hill, A. V. S. & Ewer, K. J., 7 Feb 2025, (E-pub ahead of print) In: EBioMedicine. 113, p. 105570

  Research output: Contribution to journal › Article › peer-review

  • Clinical Trial 100%
  • Tolerability 100%
  • Immunogenicity 100%
  • Crohn's Disease 100%
  • Poxviridae 100%
• 2019

  Scientific Business Abstracts of the 113th Annual Meeting of the Association of Physicians of Great Britain and Ireland

  DDD Study, 1 Sept 2019, In: QJM. 112, 9, p. 724-729 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)
• 2018

  Results of a placebo-controlled double blind randomised trial to investigate the efficacy of rifaximin-alpha versus placebo in improving systemic inflammation in patients with cirrhosis and chronic hepatic encephalopathy (RIFSYS Trial)

  Patel, V., Mcphail, M. J. W., Zamalloa, A., Stoy, S., Vijay, G. M., Huang, X., Rogers, G., Choo, J., Edwards, L., Gray, E., Woodhouse, C., Gencer, S., Coen, M., Wendon, J., Bruce, K. & Shawcross, D., Apr 2018, In: Journal of Hepatology. 68, p. S107-S108

  Research output: Contribution to journal › Meeting Abstract › peer-review
• 2016

  ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations

  Stoica, R., Paillusson, S., Gomez-Suaga, P., Mitchell, J. C., Lau, D. H. W., Gray, E. H., Sancho, R. M., Vizcay-Barrena, G., De Vos, K. J., Shaw, C., Hanger, D. P., Noble, W. & Miller, C. C. J., 1 Sept 2016, In: EMBO Reports. 17, 9, p. 1326-1342 e201541726.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Association 100%
  • Mitochondrion 100%
  • Amyotrophic Lateral Sclerosis 100%
  • Endoplasmic reticulum 100%
  • Frontotemporal Lobar Degeneration 100%
  215 Citations (Scopus)

  263 Downloads (Pure)
• 2014

  A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility

  Damotte, V., Guillot-noel, L., Patsopoulos, N. A., Madireddy, L., El Behi, M., Ban, M., Baranzini, S., Barcellos, L., Beecham, G., Beecham, A., Bernardinelli, L., Booth, D., Bos, S., Buck, D., Bush, W., Comabella, M., Compston, A., Cotsapas, C., Cournu-rebeix, I. & Cree, B. & 118 others, D'alfonso, S., Daly, M., Damotte, V., Davis, M., De Bakker, P., De Jager, P. L., Dubois, B., Esposito, F., Fontaine, B., Goris, A., Gourraud, P.-A., Green, T., Gulowsen Celius, E., Hadjixenofontos, A., Hafler, D., Haines, J., Flinstad, H. F., Hauser, S., Hawkins, C., Hemmer, B., Hillert, J., Hintzen, R., Horáková, D., Ivinson, A. J., Kemppinen, A., Kira, J.-I., Kockum, I., Lincoln, R., Martin, R., Martinelli Boneschi, F., Mccauley, J. L., Mero, I.-L., Oksenberg, J., Olsson, T., Oturai, A., Palotie, A., Patsopoulos, N., Pericak-vance, M., Rioux, J., Saarela, J., Sawcer, S., Schnetz-boutaud, N., Sellebjerg, F., Soendergaard, H., Soelberg Sorensen, P., Spurkland, A., Stankovich, J., Stewart, G., Taylor, B., Ticca, A., West, S., Zipp, F., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Donnelly, P., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., Mccann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M. J., Weston, P., Widaa, S., Whittaker, P., Barroso, I., Deloukas, P., Dilthey, A., Leslie, S., Moutsianas, L., Perez, M. L., Mcvean, G., Mathew, C. G., Blackwell, J. M., Brown, M. A., Corvin, A., Mccarthy, M. I., Spencer, C. C. A., De Jager, P. L., Baranzini, S. E., Cournu-rebeix, I. & Fontaine, B., Mar 2014, In: GENES AND IMMUNITY. 15, 2, p. 126-132 7 p., N/A.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cell Adhesion 100%
  • Gene 100%
  • Multiple Sclerosis 100%
  • Single Nucleotide Polymorphism 22%
  • ICAM3 11%
  27 Citations (Scopus)
• 2013

  Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production

  Vagnoni, A., Glennon, E., Perkinton, M., Gray, E., Noble, W. & Miller, C., 15 Nov 2013, In: Human Molecular Genetics. 22, 22, p. 4646-4652 7 p., N/A.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • N-Terminus 100%
  • Nerve Fiber Transport 100%
  • Kinesin 25%
  • Posttranslational Modification 16%
  • Transport Protein 16%
  15 Citations (Scopus)

  134 Downloads (Pure)
• 2012

  Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production

  Vagnoni, A., Perkinton, M. S., Gray, E. H., Francis, P. T., Noble, W. & Miller, C. C. J., 1 Jul 2012, In: Human Molecular Genetics. 21, 13, p. 2845-2854 10 p., N/A.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nerve Fiber Transport 100%
  • Posttranslational Modification 20%
  • Kinesin 20%
  • Small Interfering RNA 20%
  • Reduction (Chemistry) 10%
  100 Citations (Scopus)

  139 Downloads (Pure)

• Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

  Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Ståhle, M., Burden, A. D., Smith, C. H. & Cork, M. J. & 31 others, Estivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Onoufriadis, A., Weale, M. E., Campbell, L. E., Mathew, C. G., Plomin, R., Viswanathan, A. C., Gray, E., Weston, P., Barker, J. N. W. N., Trembath, R. C. & Collaborative Association Study of Psoriasis (CASP), Dec 2012, In: Nature Genetics. 44, 12, p. 1341-1348 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Candidate Gene 100%
  • Genetics 50%
  • Genetic Architecture 50%
  • RUNX3 50%
  • CARM1 50%
  818 Citations (Scopus)
• 2010

  Deficiency of the Copper Chaperone for Superoxide Dismutase Increases Amyloid-beta Production

  Gray, E. H., De Vos, K. J., Dingwall, C., Perkinton, M. S. & Miller, C. C. J., 2010, In: JOURNAL OF ALZHEIMERS DISEASE. 21, 4, p. 1101 - 1105 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Beta Amyloid 100%
  • Copper 100%
  • Superoxide 100%
  • Brain 16%
  • Enzymes 16%
  27 Citations (Scopus)
• 1981

  Trypsin separates synaptic junctions to reveal pre- and post-synaptic concanavalin A receptors

  Gordon-Weeks, P. R., Jones, D. H., Gray, E. & Barron, J., 24 Aug 1981, In: Brain research. 219, 1, p. 224-230 7 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)