King's College London

Research portal

Mr Evangelos Triantafyllou

  1. OSTEOPONTIN, MACROPHAGE MANNOSE RECEPTOR AND SOLUBLE PD-L1 ARE UPREGULATED MACROPHAGE ACTIVATION MARKERS IN PATIENTS WITH ACUTE LIVER FAILURE

    Cavazza, A., Huang, X., Triantafyllou, E., Ma, Y., Antoniades, C. G., Lee, W. M., McPhail, M. J. & Karvellas, C. J., Oct 2021, In: Hepatology. 74, p. 164A-165A

    Research output: Contribution to journalMeeting Abstractpeer-review

  2. Suppressor CD4+T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis

    Khamri, W., Gudd, C., Liu, T., Nathwani, R., Krasniqi, M., Azam, S., Barbera, T., Trovato, F. M., Possamai, L., Triantafyllou, E., Seoane, R. C., Lebosse, F., Singanayagam, A., Kumar, N., Bernsmeier, C., Mukherjee, S., McPhail, M., Weston, C. J., Antoniades, C. G. & Thursz, M. R., 3 Aug 2021, (E-pub ahead of print) In: Gut. 324071.

    Research output: Contribution to journalArticlepeer-review

  3. Dysregulation of the Lysophosphatidylcholine/Autotaxin/Lysophosphatidic Acid Axis in Acute-on-Chronic Liver Failure Is Associated With Mortality and Systemic Inflammation by Lysophosphatidic Acid–Dependent Monocyte Activation

    Trovato, F. M., Zia, R., Napoli, S., Wolfer, K., Huang, X., Morgan, P. E., Husbyn, H., Elgosbi, M., Lucangeli, M., Miquel, R., Wilson, I., Heaton, N. D., Heneghan, M. A., Auzinger, G., Antoniades, C. G., Wendon, J. A., Patel, V. C., Coen, M., Triantafyllou, E. & McPhail, M. J., Aug 2021, In: Hepatology. 74, 2, p. 907-925 19 p.

    Research output: Contribution to journalArticlepeer-review

  4. Low baseline cortisol but not delta cortisol relates to 28-day transplant-free survival in acute liver failure syndromes

    Roth, S., Flint, E., Ghataore, L., Patel, V. C., Singanayagam, A., Vincent, R. P., Triantafyllou, E., Ma, Y., Bernal, W., Auzinger, G., Heneghan, M., McPhail, M., Antoniades, C., Christ-Crain, M., Taylor, D. R., Wendon, J. & Bernsmeier, C., Jul 2021, In: Journal of Hepatology. 75, p. S306-S306

    Research output: Contribution to journalMeeting Abstractpeer-review

  5. PD-L1 expression of monocytes relates to severity, infection and mortality in acute-on-chronic liver failure

    Triantafyllou, E., Trovato, F., Husbyn, H., Huang, X., Mukherjee, S., Bernsmeier, C., Goldin, R. D., Wendon, J., Possamai, L., Khamri, W., Thursz, M. & McPhail, M. J. W., Jul 2021, In: Journal of Hepatology. 75, p. S208-S208

    Research output: Contribution to journalMeeting Abstractpeer-review

  6. Autotaxin mediates lipid dysregulation in acute-on-chronic liver failure, promoting persistence of systemic inflammation via lysophosphatidic acid-mediated monocyte activation

    McPhail, M. J. W., Trovato, F., Triantafyllou, E., Zia, R., Wolfer, K., Huang, X., Rabinowich, L., Patel, V. C., Holmes, E., Heaton, N., Heneghan, M., Bernal, W., Auzinger, G., Coen, M., Wendon, J. & Antoniades, H., Apr 2019, In: Journal of Hepatology. 70, p. E91-E92

    Research output: Contribution to journalMeeting Abstractpeer-review

  7. Immunometabolic profiling of ascites from patients with acute-on-chronic liver failure reveals increased MerTK plus immunosuppressive myeloid cells and cell death markers with preferential lipid metabolism compared to cirrhosis without organ failure

    Singanayagam, A., Erminelli, D., Triantafyllou, E., Bernsmeier, C., Tunc, E., Krasniqi, M., Patel, V., Lebosse, F., Nathwani, R., Atkinson, A., Dhar, A., Heneghan, M., Auzinger, G., Khamri, W., Adams, D., Wendon, J., Thursz, M., McPhail, M. J. W. & Antoniades, H., Apr 2019, In: Journal of Hepatology. 70, p. E183-E183

    Research output: Contribution to journalMeeting Abstractpeer-review

  8. PD-1+monocytes and macrophages contribute to impaired microbial clearance following acute liver failure

    Triantafyllou, E., Gudd, C., Nathwani, R., Trovato, F., Possamai, L., Morrison, R., Bernsmeier, C., Patel, V., Khamri, W., Goldin, R., Wendon, J., McPhail, M., Woollard, K., Thursz, M. & Antoniades, C., Apr 2019, In: Journal of Hepatology. 70, p. E430-E431

    Research output: Contribution to journalMeeting Abstractpeer-review

  9. The Role of Monocytes and Macrophages in Acute and Acute-on-Chronic Liver Failure

    Triantafyllou, E., Woollard, K. J., McPhail, M. J. W., Antoniades, C. G. & Possamai, L. A., 14 Dec 2018, In: Frontiers in Immunology. 9

    Research output: Contribution to journalReview articlepeer-review

  10. CD14+CD15-HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure

    Bernsmeier, C., Triantafyllou, E., Brenig, R., Lebosse, F. J., Singanayagam, A., Patel, V. C., Pop, O. T., Khamri, W., Nathwani, R., Tidswell, R., Weston, C. J., Adams, D. H., Thursz, M. R., Wendon, J. A. & Antoniades, C. G., Jun 2018, In: Gut. 67, 6, p. 1155-1167

    Research output: Contribution to journalArticlepeer-review

  11. PLASMA S100A8/A9: A NOVEL MECHANISTIC BIOMARKER IN INNATE IMMUNE ACTIVATION IN ACUTE-ON-CHRONIC LIVER FAILURE

    Singanayagam, A., Nathwani, R., Triantafyllou, E., Patel, V. C., Dhar, A., McPhail, M., Bernsmeier, C., Wendon, J. & Antoniades, C. G., Jun 2018, In: Gut. 67, p. A131-A132

    Research output: Contribution to journalMeeting Abstractpeer-review

  12. MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure

    Triantafyllou, E., Pop, O. T., Possamai, L. A., Wilhelm, A., Liaskou, E., Singanayagam, A., Bernsmeier, C., Khamri, W., Petts, G., Dargue, R., Davies, S. P., Tickle, J., Yuksel, M., Patel, V. C., Abeles, R. D., Stamataki, Z., Curbishley, S. M., Ma, Y., Wilson, I. D., Coen, M., & 7 othersWoollard, K. J., Quaglia, A., Wendon, J., Thursz, M. R., Adams, D. H., Weston, C. J. & Antoniades, C. G., Feb 2018, In: Gut. 67, 2, p. 333-347 15 p.

    Research output: Contribution to journalArticlepeer-review

  13. Increased Expression of CTLA4 by T Cells, Induced by B7 in Sera, Reduces Adaptive Immunity in Patients With Acute Liver Failure

    Khamri, W., Abeles, R. D., Hou, T. Z., Anderson, A. E., El-Masry, A., Triantafyllou, E., Bernsmeier, C., Larsen, F. S., Singanayagam, A., Kudo, N., Possamai, L. A., Lebosse, F., Auzinger, G., Bernal, W., Willars, C., Weston, C. J., Lombardi, G., Wendon, J., Thursz, M. & Antoniades, C. G., 28 Mar 2017, (E-pub ahead of print) In: Gastroenterology. 153, p. 263-276 e8.

    Research output: Contribution to journalArticlepeer-review

  14. Role of expression of the tumour-associated macrophage receptor, MERTK, in hepatocellular carcinoma: Spring Meeting for Clinician Scientists in Training 2017

    Mukherjee, S., Pop, O., Triantafyllou, E., Khamri, W., Curbishley, S., Thursz, M., Adams, D. & Antoniades, C., Feb 2017, In: Lancet. 389, Supplement 1, p. S72

    Research output: Contribution to journalPoster abstractpeer-review

  15. Multivariate metabotyping of plasma accurately predicts survival in patients with decompensated cirrhosis.

    McPhail, M., Shawcross, D. L., Lewis, M. R., Coltart, I., Want, E. J., Antoniades, C. G., Veselkov, K., Triantafyllou, E., Patel, V. C., Pop, O. T., Gomez-Romero, M., Kyriakides, M., Zia, R., Abeles, R. D., Crossey, M. M. E., Jassem, W., O'Grady, J., Heaton, N., Auzinger, G., Bernal, W., & 6 othersQuaglia, A., Coen, M., Nicholson, J. K., Wendon, J. A., Holmes, E. & Taylor-Robinson, S. D., May 2016, In: Journal of Hepatology. 64, 5, p. 1058-1067

    Research output: Contribution to journalArticlepeer-review

  16. High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial

    Larsen, F. S., Schmidt, L. E., Bernsmeier, C., Rasmussen, A., Isoniemi, H., Patel, V., Triantafyllou, E., Bernal, W., Auzinger, G., Shawcross, D., Eefsen, M., Bjerring, P. N., Clemmesen, J. O., Hockerstedt, K., Frederiksen, H-J., Hansen, B. A., Antoniades, C. G. & Wendon, J., 1 Jan 2016, In: Journal of Hepatology. 64, 1, p. 69-78

    Research output: Contribution to journalArticlepeer-review

  17. Patients With Acute-on-Chronic Liver Failure Have Increased Numbers of Regulatory Immune Cells Expressing the Receptor Tyrosine Kinase MERTK

    Bernsmeier, C., Pop, O. T., Singanayagam, A., Triantafyllou, E., Patel, V. C., Weston, C. J., Curbishley, S., Sadiq, F., Vergis, N., Khamri, W., Bernal, W., Auzinger, G., Heneghan, M., Ma, Y., Jassem, W., Heaton, N. D., Adams, D. H., Quaglia, A., Thursz, M. R., Wendon, J., & 1 othersAntoniades, C. G., Mar 2015, In: Gastroenterology. 148, 3, p. 603-615.e14 27 p.

    Research output: Contribution to journalArticlepeer-review

  18. Acute alcoholic hepatitis and cellular Th1 immune responses to alcohol dehydrogenase

    Blackmore, L. J., Ryan, J. M., Huang, X., Hussain, M., Triantafyllou, E., Vergis, N., Manakkat Vijay, G., Antoniades, C. G., Thursz, M. R., Jassem, W., Vergani, D., Shawcross, D. L. & Ma, Y., 26 Feb 2015, In: Lancet. 385 , S1, p. S22-S22 1 p., 61.

    Research output: Contribution to journalPoster abstractpeer-review

  19. PROOF-OF-PRINCIPLE EVALUATION OF IMMUNOMODULATORY DRUGS IN PROMOTING PHAGOCYTOSIS CAPACITY IN PATIENTS WITH LIVER FAILURE.

    Bernsmeier, C., Tidswell, R., Ghataore, L., Patel, V. C., Singanayagam, A., Triantafyllou, E., Khamri, W., Heneghan, M., Willars, C., Bernal, W., Auzinger, G., Taylor, D. R., Vincent, R., Ma, Y., Thursz, M. R., Wendon, J. & Antoniades, C., 2015, In: Journal of Hepatology. 62, p. S324 1 p., P1294.

    Research output: Contribution to journalMeeting abstractpeer-review

  20. Secretory leukocyte protease inhibitor: A pivotal mediator of anti-inflammatory responses in acetaminophen-induced acute liver failure

    Antoniades, C. G., Khamri, W., Abeles, R. D., Taams, L. S., Triantafyllou, E., Possamai, L. A., Bernsmeier, C., Mitry, R. R., O'Brien, A., Gilroy, D., Goldin, R., Heneghan, M., Heaton, N., Jassem, W., Bernal, W., Vergani, D., Ma, Y., Quaglia, A., Wendon, J. & Thursz, M., 24 Mar 2014, In: Hepatology. 59, 4, p. 1564-1576 13 p.

    Research output: Contribution to journalArticlepeer-review

  21. Could targeting secretory leukocyte protease inhibitor be an effective therapeutic option to prevent infections in acute liver failure?

    Possamai, L. A., Khamri, W., Triantafyllou, E., Wendon, J. A., Thursz, M. R. & Antoniades, C. G., 2014, In: Immunotherapy. 6, 6, p. 667-9 3 p.

    Research output: Contribution to journalArticlepeer-review

  22. Increased apoptotic activity is associated with hospital mortality and disruption in lipid homeostasis in acute-on-chronic liver failure.

    McPhail, M., Triantafyllou, E., Shawcross, D., Antoniades, C. G., Lewis, M. R., Want, E., Patel, V. C., Pasha, Y., Abeles, D., Bernal, W., Holmes, E., Wendon, J. & Taylor-Robinson, S. D., Oct 2013, In: Hepatology. 58, p. 851A-852A 2 p., 1324.

    Research output: Contribution to journalMeeting abstractpeer-review

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