Research output per year
Research output per year
Personal profile
Biographical details
Dr. Flavio Dell'Acqua is a Reader (Associate Professor) in Translational Neuroimaging at King's College London's Institute of Psychiatry, Psychology and Neuroscience (IoPPN). His research focuses on neuroscience and medical imaging research, developing and implementing new Diffusion MRI and Tractography techniques to study brain connections in health and disease.
At the IoPPN, he co-founded the NatBrainLab, a multidisciplinary team for neuroanatomical research and methodological development in brain imaging. His work bridges the gap between technical innovation in diffusion imaging and practical clinical applications, including methods licensed through King's College London and implemented in FDA-certified clinical software.
Dr. Dell'Acqua completed his Bachelor's and Master's degree in Biomedical Engineering at the Polytechnic of Milan, followed by a PhD in Biomedical Technologies from the University of Milano-Bicocca. Following his PhD, he joined King's College London as a Post-Doctoral Research Scientist, where he has since established himself as key investigator in major international projects including the EU-AIMS Longitudinal European Autism Project and iMarkHD, a longitudinal neuroimaging study of Huntington's Disease.
He is involved in multiple collaborations involving microstructure imaging and brain connectivity across major institutions in the UK, Europe, USA, Canada and New Zealand, including partnerships with pharmaceutical companies and research foundations.
Dr. Dell'Acqua has served as Chair of the Diffusion Study Group at the International Society for Magnetic Resonance in Medicine (ISMRM) and currently holds the position of Vice-President of the International Society for Tractography (IST). He is the Chief Editor of "The Handbook of Diffusion MRI Tractography" published by Elsevier in 2024 and has published over 100 peer-reviewed papers in the field of neuroimaging.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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A multimodal neural signature of face processing in autism within the fusiform gyrus
EU-AIMS LEAP group, Jan 2025, In: Nature Mental Health . 3, 1, p. 31-45 15 p., 43.Research output: Contribution to journal › Article › peer-review
Open Access -
Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 1: In vivo small-animal imaging
Jelescu, I. O., Grussu, F., Ianus, A., Hansen, B., Barrett, R. L. C., Aggarwal, M., Michielse, S., Nasrallah, F., Syeda, W., Wang, N., Veraart, J., Roebroeck, A., Bagdasarian, A. F., Eichner, C., Sepehrband, F., Zimmermann, J., Soustelle, L., Bowman, C., Tendler, B. C. & Hertanu, A. & 37 others, , Jun 2025, In: Magnetic Resonance in Medicine. 93, 6, p. 2507-2534 28 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 2-Ex vivo imaging: Added value and acquisition
Schilling, K. G., Grussu, F., Ianus, A., Hansen, B., Howard, A. F. D., Barrett, R. L. C., Aggarwal, M., Michielse, S., Nasrallah, F., Syeda, W., Wang, N., Veraart, J., Roebroeck, A., Bagdasarian, A. F., Eichner, C., Sepehrband, F., Zimmermann, J., Soustelle, L., Bowman, C. & Tendler, B. C. & 38 others, , Jun 2025, In: Magnetic Resonance in Medicine. 93, 6, p. 2535-2560 26 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Considerations and recommendations from the ISMRM Diffusion Study Group for preclinical diffusion MRI: Part 3-Ex vivo imaging: Data processing, comparisons with microscopy, and tractography
Schilling, K. G., Howard, A. F. D., Grussu, F., Ianus, A., Hansen, B., Barrett, R. L. C., Aggarwal, M., Michielse, S., Nasrallah, F., Syeda, W., Wang, N., Veraart, J., Roebroeck, A., Bagdasarian, A. F., Eichner, C., Sepehrband, F., Zimmermann, J., Soustelle, L., Bowman, C. & Tendler, B. C. & 38 others, , Jun 2025, In: Magnetic Resonance in Medicine. 93, 6, p. 2561-2582 22 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Zero-phase-delay connectivity increases the reliability, concordance with structure, and prognostic ability of functional connectivity metrics
Mehra, C., Beyh, A., Laiou, P., Garces, P., Murphy, D., Loth, E., Dell' Acqua, F., Ewen, J. B., Richardson, M. & O'Muircheartaigh, J., 4 Jan 2025.Research output: Working paper/Preprint › Preprint
Open Access
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Early Biomarkers of Alzheimer’s Disease in Down Syndrome: Targeting Brain’s Microstructure and Metabolism
Dell' Acqua, F. (Primary Investigator)
1/10/2024 → 30/09/2026
Project: Research
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Initiation,: iMarkHD: Longitudinal Adaptive Study of Molecular Pathology and Neuronal Networks in Huntington's Disease Gene Expansion Carriers (HDGEC) and Healthy Controls using Positron Emission Tomography (PET) and Multi-modal Magnetic Resonance Imaging (MRI)
Williams, S. (Primary Investigator), Dell' Acqua, F. (Co-Investigator), Ginestet, C. (Co-Investigator), Lythgoe, D. (Co-Investigator), O'Daly, O. (Co-Investigator), Veronese, M. (Co-Investigator), Wood, T. (Co-Investigator), Zelaya, F. (Co-Investigator), academic, A. (Co-Investigator) & van Wamelen, D. (Co-Investigator)
1/11/2020 → 30/09/2028
Project: Research
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AIMS-2-TRIALS: Autism Innovative Medicine Studies – 2 – Trials
Murphy, D. (Primary Investigator), McAlonan, G. (Co-Investigator), Loth, E. (Co-Investigator), O'Muircheartaigh, J. (Co-Investigator), Dell' Acqua, F. (Co-Investigator), Daly, E. (Co-Investigator), Strydom, A. (Co-Investigator), Simonoff, E. (Co-Investigator), Richardson, M. (Co-Investigator), Marin, O. (Co-Investigator), Rico, B. (Co-Investigator), Charman, T. (Co-Investigator), Edwards, D. (Co-Investigator), Rutherford, M. (Co-Investigator), Hajnal, J. (Co-Investigator), Hotopf, M. (Co-Investigator) & Dobson, R. (Co-Investigator)
1/06/2018 → 30/11/2026
Project: Research
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LonDownsPREVENT: A longitudinal study of the mechanisms of cerebral amyloid angiopathy and neurodegeneration in Down syndrome to inform AD prevention
Strydom, A. (Primary Investigator), Dell' Acqua, F. (Co-Investigator), Williams, S. (Co-Investigator) & Emsley, R. (Co-Investigator)
1/02/2019 → 30/04/2023
Project: Research
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GLioblastoma Infiltration and Advanced DIffusion MRI - the GLIA-DIM study
Dell' Acqua, F. (Primary Investigator), Catani, M. (Co-Investigator) & Stahl, D. (Co-Investigator)
1/02/2017 → 31/01/2020
Project: Research