Research output per year
Research output per year
Personal profile
Research interests
My main research interests include :
The biology of periodontal regeneration, including understanding the lineage and differentiation of cells of the periodontium, the factors that may regulate bone formation and translating tissue engineering principles for novel periodontal therapies;
Risk and prognostic factors and biomarkers for periodontal disease. We are interested in the wide range of environmental, genetic and humoral risk and prognostic factors that may interact to determine susceptibility to periodontitis and how these factors may act. We have become particularly interested in applying proteomic technologies to identify and test for salivary diagnostics which may be useful in the clinic, and ultimately aspire to applying this knowledge for the development of new periodontal treatments.
Research interests (short)
Periodontology ; periodontal regeneration; periodontal ligament; growth factors; osteoblasts; dental stem cells, risk factors, prognosis, saliva, biomarkers, proteomics, clinical trials
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of London
Award Date: 1 Jan 1988
Bachelor of Dental Surgery, University of London
Award Date: 1 Jan 1979
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Association between calcium-channel blockers and gingival enlargement: A case-control study
Mainas, G., Santamaria, P., Zoheir, N., Alamri, M., Hughes, F., Lu, E. M. C. & Nibali, L., Oct 2024, In: Journal of Dentistry. 149, 105315.Research output: Contribution to journal › Article › peer-review
Open Access -
Can periodontal measures assist in the identification of adults with undiagnosed hyperglycaemia? A systematic review: A systematic review
Talakey, A. A., Hughes, F. J. & Bernabé, E., Apr 2022, In: Journal of Clinical Periodontology. 49, 4, p. 302-312 11 p.Research output: Contribution to journal › Article › peer-review
File3 Citations (Scopus)51 Downloads (Pure) -
Regulation of gingival fibroblast phenotype by periodontal ligament cells in vitro
Garna, D. F., Hughes, F. J. & Ghuman, M. S., Apr 2022, In: Journal of Periodontal Research. 57, 2, p. 402-411 10 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Retrospective exploratory study of smoking status and e-cigarette use with response to non-surgical periodontal therapy
Shah, C., Holtfreter, B., Hughes, F. J. & Nibali, L., 2022, (Accepted/In press) In: Journal of Periodontology.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
External Validation of a Periodontal Prediction Model for Identification of Diabetes among Saudi Adults
Talakey, A. A., Hughes, F. & Bernabé, E., 2021, In: Journal of Contemporary Dental Practice. 21, 10, p. 1176-1181 6 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Projects
- 12 Finished
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Validation of Oral Health Assessment in Twins UK Study Cohort
Ide, M. (Primary Investigator) & Hughes, F. (Co-Investigator)
Oral and Dental Research Trust
1/10/2015 → 30/08/2017
Project: Research
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Epithelial mesenchymal interactions in the regulation of the dentogingival junction in periodontitis.
Ghuman, M. (Primary Investigator), Gharibi, B. (Co-Investigator), Green, J. (Co-Investigator) & Hughes, F. (Co-Investigator)
1/03/2015 → 29/02/2016
Project: Research
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Periodontal disease as a screening tool for undiagnosed diabetes
Bernabe, E. (Primary Investigator), Gulliford, M. (Co-Investigator) & Hughes, F. (Co-Investigator)
1/07/2014 → 30/06/2015
Project: Research
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The role of DDIT4/mTOR signalling in the regulation of aging in mesenchymal stem cells
Hughes, F. (Primary Investigator) & Ghuman, M. (Co-Investigator)
1/07/2014 → 30/06/2015
Project: Research
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Development of diagnostic and prognostic salivary biomarkers for periodontal disease - PERSAL
Proctor, G. (Primary Investigator) & Hughes, F. (Co-Investigator)
1/01/2013 → 31/12/2017
Project: Research
Activities
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Europerio 8 London 2015
Hughes, F. (Chair)
2011 → 2015Activity: Other › Types of External academic engagement - Membership of external research organisation
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British Society of Periodontology
Hughes, F. (President)
2009 → 2010Activity: Other › Types of External academic engagement - Membership of external research organisation
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Journal of Periodontal Research (Journal)
Hughes, F. (Editorial board member)
2009 → …Activity: Publication peer-review and editorial work › Editorial activity
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Pan European Federation, International Association for Dental Research
Hughes, F. (President)
2007 → 2009Activity: Other › Types of External academic engagement - Membership of external research organisation
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Journal of Dental Research (Journal)
Hughes, F. (Editorial board member)
2006 → 2012Activity: Publication peer-review and editorial work › Editorial activity