King's College London

Research portal

Professor Francis Hughes

  1. Regulation of gingival fibroblast phenotype by periodontal ligament cells in vitro

    Garna, D. F., Hughes, F. J. & Ghuman, M. S., Apr 2022, In: Journal of Periodontal Research. 57, 2, p. 402-411 10 p.

    Research output: Contribution to journalArticlepeer-review

  2. Retrospective exploratory study of smoking status and e-cigarette use with response to non-surgical periodontal therapy

    Shah, C., Holtfreter, B., Hughes, F. J. & Nibali, L., 2022, (Accepted/In press) In: Journal of Periodontology.

    Research output: Contribution to journalArticlepeer-review

  3. Increasing awareness of drug induced gingival enlargement

    Hughes, F. J., 21 Jun 2021, In: The BMJ. 373, n1571.

    Research output: Contribution to journalLetterpeer-review

  4. Differential regulation of epithelial growth by gingival and periodontal fibroblasts in vitro

    Lu, E. M. C., Hobbs, C., Dyer, C., Ghuman, M. & Hughes, F. J., Dec 2020, In: Journal of Periodontal Research. 55, 6, p. 859-867 9 p.

    Research output: Contribution to journalArticlepeer-review

  5. Development of an in vitro model of the dentogingival junction using 3D organotypic constructs

    Lu, E. M. C., Hobbs, C., Ghuman, M. & Hughes, F. J., 3 Oct 2020, In: Journal of Periodontal Research. 56, 1, 147 p.

    Research output: Contribution to journalArticlepeer-review

  6. Is the Performance of a Periodontal Prediction Model for Identification of Diabetes affected by Participants' Characteristics?

    Talakey, A., Hughes, F., Almoharib, H., AlAskar, M. & Bernabe, E., 3 Sep 2020, (E-pub ahead of print) In: Community Dental Health.

    Research output: Contribution to journalArticlepeer-review

  7. Comparison of the expression of periodontal markers in dental and bone marrow-derived mesenchymal stem cells

    Garna, D., Kaur, M., Hughes, F. J. & Ghuman, M., 1 Jan 2020, In: Open Dentistry Journal. 14, 1, p. 196-202 7 p.

    Research output: Contribution to journalArticlepeer-review

  8. The added value of periodontal measurements for identification of diabetes among Saudi adults

    Talakey, A. A., Hughes, F., Almoharib, H., Al-Askar, M. & Bernabé, E., 1 Jan 2020, (Accepted/In press) In: Journal of Periodontology.

    Research output: Contribution to journalArticlepeer-review

  9. Gingival fibroblasts prevent BMP-mediated osteoblastic differentiation

    Ghuman, M. S., Al-Masri, M., Xavier, G., Cobourne, M. T., McKay, I. J. & Hughes, F. J., Jun 2019, In: Journal of Periodontal Research. 54, 3, p. 300-309 10 p.

    Research output: Contribution to journalArticlepeer-review

  10. Periodontal diagnosis in the context of the 2017 classification system of periodontal diseases and conditions: Presentation of a patient with periodontitis localised to the molar teeth

    Wadia, R., Walter, C., Chapple, I. L. C., Ower, P., Tank, M., West, N. X., Needleman, I., Hughes, F. J., Milward, M. R., Hodge, P. J. & Dietrich, T., 8 Feb 2019, In: British Dental Journal. 226, 3, p. 180-182 3 p.

    Research output: Contribution to journalArticlepeer-review

  11. Periodontal diagnosis in the context of the 2017 classification system of periodontal diseases and conditions: Presentation of a middle-aged patient with localised periodontitis

    Walter, C., Ower, P., Tank, M., West, N. X., Needleman, I., Hughes, F. J., Wadia, R., Milward, M. R., Hodge, P. J., Chapple, I. L. C. & Dietrich, T., 25 Jan 2019, In: British Dental Journal. 226, 2, p. 98-100 3 p.

    Research output: Contribution to journalArticlepeer-review

  12. Periodontal diagnosis in the context of the 2017 classification system of periodontal diseases and conditions – Implementation in clinical practice

    British Society of Periodontology, 11 Jan 2019, In: British Dental Journal. 226, 1, p. 16-22 7 p.

    Research output: Contribution to journalArticlepeer-review

  13. Periodontal complications of prescription and recreational drugs

    Hughes, F. J. & Bartold, P. M., Oct 2018, In: PERIODONTOLOGY 2000. 78, 1, p. 47-58 12 p.

    Research output: Contribution to journalReview articlepeer-review

  14. Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations

    Albandar, J. M., Susin, C. & Hughes, F. J., 1 Jun 2018, In: Journal of Periodontology. 89, p. S183-S203

    Research output: Contribution to journalArticlepeer-review

  15. Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions

    Jepsen, S., Caton, J. G., Albandar, J. M., Bissada, N. F., Bouchard, P., Cortellini, P., Demirel, K., de Sanctis, M., Ercoli, C., Fan, J., Geurs, N. C., Hughes, F. J., Jin, L., Kantarci, A., Lalla, E., Madianos, P. N., Matthews, D., McGuire, M. K., Mills, M. P., Preshaw, P. M., & 5 othersReynolds, M. A., Sculean, A., Susin, C., West, N. X. & Yamazaki, K., 1 Jun 2018, In: Journal of Clinical Periodontology. 45, p. S219-S229

    Research output: Contribution to journalArticlepeer-review

  16. Silicon nitride (Si3N4) implants: The future of dental implantology?

    Badran, Z., Struillou, X., Hughes, F. J., Soueidan, A., Hoornaert, A. & Ide, M., 1 Jun 2017, In: JOURNAL OF ORAL IMPLANTOLOGY. 43, 3, p. 240-244 5 p.

    Research output: Contribution to journalReview articlepeer-review

  17. T2 relaxation mapping MRI of healthy and inflamed gingival tissue

    Newbould, R. D., Bishop, C. A., Janiczek, R. L., Parkinson, C. & Hughes, F. J., 2017, In: DENTOMAXILLOFACIAL RADIOLOGY. 46, 2, 20160295.

    Research output: Contribution to journalArticlepeer-review

  18. DDIT4 regulates mesenchymal stem cell fate by mediating between HIF1α and mTOR signalling

    Gharibi, B., Ghuman, M. & Hughes, F. J., 23 Nov 2016, In: Scientific Reports. 6, 36889.

    Research output: Contribution to journalArticlepeer-review

  19. The effect of an Er,Cr: YSGG laser in the management of intrabony defects associated with chronic periodontitis using minimally invasive closed flap surgery. A case series

    Al-Falaki, R., Hughes, F., Wadia, R., Eastman, C., Kontogiorgos, E. & Low, S. B., 30 Jun 2016, In: Laser Therapy. 25, 2, p. 131-139 9 p.

    Research output: Contribution to journalArticlepeer-review

  20. Replication of the association of GLT6D1 with aggressive periodontitis in a Sudanese population

    Hashim, N. T., Linden, G. J., Ibrahim, M. E., Gismalla, B. G., Lundy, F. T., Hughes, F. J. & El Karim, I. A., Apr 2015, In: Journal of Clinical Periodontology. 42, 4, p. 319-324 6 p.

    Research output: Contribution to journalArticlepeer-review

  21. Transcriptomic analysis of three Veillonella spp. present in carious dentine and in the saliva of caries-free individuals

    Do, T., Sheehy, E. C., Mulli, T., Hughes, F. & Beighton, D., 26 Mar 2015, In: Frontiers in Cellular and Infection Microbiology. 5, p. 25 1 p.

    Research output: Contribution to journalArticlepeer-review

  22. Periodontium and Periodontal Disease

    Hughes, F. J., 1 Jan 2015, Stem Cell Biology and Tissue Engineering in Dental Sciences. Elsevier Inc., p. 433-444 12 p.

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  23. Diabetes and periodontal disease: A two-way relationship

    Casanova, L., Hughes, F. J. & Preshaw, P. M., 27 Oct 2014, In: British Dental Journal. 217, 8, p. 433-437 5 p.

    Research output: Contribution to journalArticlepeer-review

  24. Periodontitis-the new caries?

    Hughes, F., 27 Oct 2014, In: British Dental Journal. 217, 8, p. 387-387 1 p.

    Research output: Contribution to journalEditorialpeer-review

  25. Treatment outcome following use of the erbium, chromium:yttrium, scandium, gallium, garnet laser in the non-surgical management of peri-implantitis: A case series

    Al-Falaki, R., Cronshaw, M. & Hughes, F. J., 27 Oct 2014, In: British Dental Journal. 217, 8, p. 453-457 5 p.

    Research output: Contribution to journalArticlepeer-review

  26. Drugs, medications and periodontal disease

    Heasman, P. A. & Hughes, F. J., 24 Oct 2014, In: British Dental Journal. 217, 8, p. 411-419 9 p.

    Research output: Contribution to journalArticlepeer-review

  27. Inhibition of Akt/mTOR attenuates age-related changes in mesenchymal stem cells

    Gharibi, B., Farzadi, S., Ghuman, M. & Hughes, F. J., Aug 2014, In: Stem cells (Dayton, Ohio). 32, 8, p. 2256-2266 11 p.

    Research output: Contribution to journalArticlepeer-review

  28. The presence, function and regulation of IL-17 and Th17 cells in periodontitis.

    Cheng, W-C., Hughes, F. & Taams, L., Jun 2014, In: Journal of Clinical Periodontology. 41, 6, p. 541-549 9 p.

    Research output: Contribution to journalArticlepeer-review

  29. Mesenchymal Stem Cells and Periodontal Regeneration

    Hughes, F. J., Mar 2014, In: Current Oral Health Reports. 1, 1

    Research output: Contribution to journalReview articlepeer-review

  30. Gene Expression Responses to Mechanical Stimulation of Mesenchymal Stem Cells Seeded on Calcium Phosphate Cement

    Gharibi, B., Cama, G., Capurro, M., Thompson, I., Deb, S., Di-Silvio, L. & Hughes, F. J., 24 Oct 2013, In: Tissue Engineering Part A. 19, 21-22, p. 2426-2438 13 p.

    Research output: Contribution to journalArticlepeer-review

  31. Effects of hydroxyapatite and PDGF concentrations on osteoblast growth in a nanohydroxyapatite-polylactic acid composite for guided tissue regeneration

    Talal, A., McKay, I. J., Tanner, K. E. & Hughes, F. J., Sep 2013, In: Journal of Materials Science: Materials in Medicine. 24, 9, p. 2211-2221 11 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  32. Periodontitis and systemic diseases: a record of discussions of working group 4 of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases

    Linden, G. J., Herzberg, M. C., Working group 4 of joint EFP/AAP workshop & Hughes, F., Apr 2013, In: Journal of Clinical Periodontology. 40 , Suppl 14, p. S20-S23 4 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  33. Langerhans cell histiocytosis: a diagnostic dilemma

    Ryan, P. L., Piper, K. M. & Hughes, F. J., Dec 2012, In: Dental Update. 39, 10, p. 716-8, 720 4 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  34. Effects of low-dose doxycycline on cytokine secretion in human monocytes stimulated with Aggregatibacter actinomycetemcomitans

    Bostanci, N., Akguel, B., Tsakanika, V., Allaker, R. P., Hughes, F. J. & McKay, I. J., Dec 2011, In: Cytokine. 56, 3, p. 656 - 661 6 p.

    Research output: Contribution to journalArticlepeer-review

  35. Host-response: understanding the cellular and molecular mechanisms of host-microbial interactions--consensus of the Seventh European Workshop on Periodontology

    Kinane, D. F., Preshaw, P. M., Loos, B. G., Working Group 2 of Seventh European Workshop on Periodontology & Hughes, F., Mar 2011, In: Journal of Clinical Periodontology. 38 , Suppl 11, p. 44-48 5 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  36. Involvement of Autoimmunity in the Pathogenesis of Aggressive Periodontitis

    Hendler, A., Mulli, T. K., Hughes, F. J., Perrett, D., Bombardieri, M., Houri-Haddad, Y., Weiss, E. I. & Nissim, A., Dec 2010, In: Journal of Dental Research. 89, 12, p. 1389 - 1394 6 p.

    Research output: Contribution to journalArticlepeer-review

  37. Periodontal regeneration: a challenge for the tissue engineer?

    Hughes, F. J., Ghuman, M. & Talal, A., Dec 2010, In: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine. 224, H12, p. 1345 - 1358 14 p.

    Research output: Contribution to journalArticlepeer-review

  38. Absorption and release of protein from hydroxyapatite-polylactic acid (HA-PLA) membranes.

    Talal, A., Waheed, N., Al-Masri, M., McKay, IJ., Tanner, KE. & Hughes, FJ., Nov 2009, In: Journal of Dentistry. 37, 11, p. 820 - 826 7 p.

    Research output: Contribution to journalArticlepeer-review

  39. Ovariectomy vs. hypofunction: their effects on rat mandibular bone.

    Rawlinson, SC., Boyde, A., Davis, GR., Howell, PG., Hughes, FJ. & Kingsmill, VJ., 1 Jul 2009, In: Journal of Dental Research. 88, 7, p. 615 - 620 6 p.

    Research output: Contribution to journalArticlepeer-review

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