King's College London

Research portal

Dr Gabriela Dontu

  1. Models of breast morphogenesis based on localization of stem cells in the developing mammary lobule

    Honeth, G., Schiavinotto, T., Vaggi, F., Marlow, R., Kanno, T., Shinomiya, I., Lombardi, S., Buchupalli, B., Graham, R., Gazinska, P., Ramalingam, V., Burchell, J., Purushotham, A. D., Pinder, S. E., Csikasz-Nagy, A. & Dontu, G., 14 Apr 2015, In : Stem Cell Reports. 4, 4, p. 699-711 13 p.

    Research output: Contribution to journalArticle

  2. Growth Hormone Is Secreted by Normal Breast Epithelium upon Progesterone Stimulation and Increases Proliferation of Stem/Progenitor Cells

    Lombardi, S., Honeth, G., Ginestier, C., Shinomiya, I., Marlow, R., Buchupalli, B., Gazinska, P., Brown, J., Catchpole, S., Liu, S., Barkan, A., Wicha, M., Purushotham, A., Burchell, J., Pinder, S. & Dontu, G., 3 Jun 2014, In : Stem Cell Reports. 2, 6, p. 780-793 14 p.

    Research output: Contribution to journalArticle

  3. Aldehyde dehydrogenase and estrogen receptor define a hierarchy of cellular differentiation in the normal human mammary epithelium

    Honeth, G., Lombardi, S., Ginestier, C., Hur, M., Marlow, R., Buchupalli, B., Shinomiya, I., Gazinska, P., Bombelli, S., Ramalingam, V., Purushotham, A. D., Pinder, S. E. & Dontu, G., 27 May 2014, In : Breast Cancer Research. 16, 3, 15 p., R52.

    Research output: Contribution to journalArticle

  4. A novel model of dormancy for bone metastatic breast cancer cells

    Marlow, R., Honeth, G., Lombardi, S., Cariati, M., Hessey, S. M., Pipili, A., Mariotti, V., Buchupalli, B., Foster, K., Bonnet, D., Grigoriadis, A., Purushotham, A., Tutt, A. & Dontu, G., Dec 2013, In : Cancer Research. 73, 23, p. 6886-6899 14 p.

    Research output: Contribution to journalArticle

  5. Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors

    Schott, A. F., Landis, M. D., Dontu, G., Griffith, K. A., Layman, R. M., Krop, I., Paskett, L. A., Wong, H., Dobrolecki, L. E., Lewis, M. T., Froehlich, A. M., Paranilam, J., Hayes, D. F., Wicha, M. S. & Chang, J. C., 15 Mar 2013, In : Clinical Cancer Research. 19, 6, p. 1512-1524 13 p.

    Research output: Contribution to journalArticle

  6. Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells through Cytokine Networks

    Liu, S., Ginestier, C., Ou, S. J., Clouthier, S. G., Patel, S. H., Monville, F., Korkaya, H., Heath, A., Dutcher, J., Kleer, C. G., Jung, Y., Dontu, G., Taichman, R. & Wicha, M. S., 15 Jan 2011, In : Cancer Research. 71, 2, p. 614 - 624 11 p.

    Research output: Contribution to journalArticle

  7. Xenotransplantation of breast cancers

    Cariati, M., Marlow, R. & Dontu, G., 2011, In : Methods in Molecular Biology. 731, N/A, p. 471-482 12 p., N/A.

    Research output: Contribution to journalArticle

  8. Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

    Kakarala, M., Brenner, D. E., Korkaya, H., Cheng, C., Tazi, K., Ginestier, C., Liu, S., Dontu, G. & Wicha, M. S., Aug 2010, In : Breast Cancer Research and Treatment. 122, 3, p. 777 - 785 9 p., N/A.

    Research output: Contribution to journalArticle

  9. CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts

    Ginestier, C., Liu, S., Diebel, M. E., Korkaya, H., Luo, M., Brown, M., Wicinski, J., Cabaud, O., Charafe-Jauffret, E., Birnbaum, D., Guan, J-L., Dontu, G. & Wicha, M. S., 1 Feb 2010, In : Journal of Clinical Investigation. 120, 2, p. 485 - 497 13 p.

    Research output: Contribution to journalArticle

  10. MicroRNAs: shortcuts in dealing with molecular complexity?

    Dontu, G. & de Rinaldis, E., 19 Jan 2010, In : Breast Cancer Research. 12, 1, 301.

    Research output: Contribution to journalEditorial

  11. Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

    Charafe-Jauffret, E., Ginestier, C., Iovino, F., Tarpin, C., Diebel, M., Esterni, B., Houvenaeghel, G., Extra, J-M., Bertucci, F., Jacquemier, J., Xerri, L., Dontu, G., Stassi, G., Xiao, Y., Barsky, S. H., Birnbaum, D., Viens, P. & Wicha, M. S., 1 Jan 2010, In : Clinical Cancer Research. 16, 1, p. 45 - 55 11 p.

    Research output: Contribution to journalArticle

  12. TARGETING BREAST CANCER STEM CELLS

    Dontu, G., 2010, In : Annals of Oncology. 21, p. 26 - 26 1 p.

    Research output: Contribution to journalMeeting abstract

  13. Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis

    Huang, E. H., Hynes, M. J., Zhang, T., Ginestier, C., Dontu, G., Appelman, H., Fields, J. Z., Wicha, M. S. & Boman, B. M., 15 Apr 2009, In : Cancer Research. 69, 8, p. 3382 - 3389 8 p.

    Research output: Contribution to journalArticle

  14. Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature

    Charafe-Jauffret, E., Ginestier, C., Iovino, F., Wicinski, J., Cervera, N., Finetti, P., Hur, M-H., Diebel, M. E., Monville, F., Dutcher, J., Brown, M., Viens, P., Xerri, L., Bertucci, F., Stassi, G., Dontu, G., Birnbaum, D. & Wicha, M. S., 15 Feb 2009, In : Cancer Research. 69, 4, p. 1302 - 1313 12 p.

    Research output: Contribution to journalArticle

  15. Targeting breast cancer stem cells through CXCR1 blockade

    Ginestier, C., Liu, S., Diebel, M., Korkaya, H., Luo, M., Dutcher, J., Brown, M., Charaffe-Jauffret, E., Birnbaum, D., Guan, J., Dontu, G. & Wicha, M., 2009, In : Journal of Clinical Investigation. 120, 2, p. 485 - 497 13 p.

    Research output: Contribution to journalArticle

  16. The metastatic phenotype of inflammatory breast cancer is associated with ALDH1 positive cells

    Charaffe-Jauffret, E., Ginestier, C., Iovino, F., Tarpin, C., Estreni, B., Jacquemier, J., Xerri, L., Dontu, G., Birnbaum, D., Viens, P. & Wicha, M., 2009, In : Clinical Cancer Research. Not known, p. 45 - 55 11 p.

    Research output: Contribution to journalArticle

  17. Stem cells and epithelial cancers: the example of breast cancer

    Charafe-Jauffret, E., Ginestier, C., Monville, F., Wicinski, J., Bertucci, F., Viens, P., Xerri, L., Cabaud, O., Dontu, G., Wicha, M. S. & Birnbaum, D., Nov 2008, In : Annales De Pathologie. 28, SUPPL. 1, p. S30 - S32

    Research output: Contribution to journalArticle

  18. Breast cancer stem cell markers - the rocky road to clinical applications

    Dontu, G., 15 Sep 2008, In : Breast Cancer Research. 10, 5, 110.

    Research output: Contribution to journalEditorial

  19. Monitoring serial changes in circulating human breast cancer cells in murine xenograft models

    Eliane, J-P., Repollet, M., Luker, K. E., Brown, M., Rae, J. M., Dontu, G., Schott, A. F., Wicha, M., Doyle, G. V., Hayes, D. F. & Luker, G. D., 15 Jul 2008, In : Cancer Research. 68, 14, p. 5529 - 5532 4 p.

    Research output: Contribution to journalArticle

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