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  A cryo-electron microscope for structural biology (including single-particle and tomography) at KCL.

  Conte, M. (Primary Investigator), Atherton, J. (Co-Investigator), Beavil, A. (Co-Investigator), Bergeron, J. (Co-Investigator), Booth, P. (Co-Investigator), Burrone, J. (Co-Investigator), Carlton, J. (Co-Investigator), De Nicola, G. (Co-Investigator), Ehler, E. (Co-Investigator), Fleck, R. (Co-Investigator), Fraternali, F. (Co-Investigator), Garnett, J. (Co-Investigator), Gautel, M. (Co-Investigator), Isaacson, R. (Co-Investigator), Kampourakis, T. (Co-Investigator), Malim, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Neil, S. (Co-Investigator), Odendall, C. (Co-Investigator), Pfuhl, M. (Co-Investigator), Politis, A. (Co-Investigator), Steiner, R. (Co-Investigator) & Sutton, B. (Co-Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council

  1/08/2022 → 31/07/2023

  Project: Research

• Can AI guided by in-crystal fragment screening crack the protein-protein interaction inhibitors problem?

  Fraternali, F. (Primary Investigator) & De Nicola, G. (Co-Investigator)

  Royal Society of Chemistry

  1/02/2022 → 1/07/2023

  Project: Research

• Isothermal titration calorimetry instrumentation for structural biology, biological mechanisms and drug discovery

  Conte, M. (Primary Investigator), Gautel, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Isaacson, R. (Co-Investigator), M. Barry, S. (Co-Investigator), Garnett, J. (Co-Investigator), Steiner, R. (Co-Investigator), Muller, M. (Co-Investigator), Pfuhl, M. (Co-Investigator), Bergeron, J. (Co-Investigator), Malim, M. (Co-Investigator), Naglik, J. (Co-Investigator), Kampourakis, T. (Co-Investigator), Burgoyne, J. (Co-Investigator), Pastore, A. (Co-Investigator) & De Nicola, G. (Co-Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council

  1/10/2020 → 30/09/2021

  Project: Research

• Using protein-protein inhibitors to target p38α during myocardial ischemia

  De Nicola, G. (Primary Investigator) & Marber, M. (Co-Investigator)

  MRC Medical Research Council

  19/05/2019 → 18/03/2020

  Project: Research

  • Protein Inhibitor 100%
  • Heart Muscle Ischemia 100%
  • Protein 100%

• Developing inhibitors of the p38a-TAB1 protein interaction

  De Nicola, G. (Primary Investigator) & Marber, M. (Co-Investigator)

  1/01/2017 → 30/06/2018

  Project: Research

• An interdisciplinary approach to p38 alpha mediated cardiac senescence

  De Nicola, G. (Primary Investigator)

  1/03/2015 → 29/02/2020

  Project: Research

• Lamin b1 as a keystone in senescence and atherosclerosis: an interdisciplinary approach

  Conte, M. (Primary Investigator), De Nicola, G. (Primary Investigator) & Shanahan, C. (Co-Investigator)

  BHF British Heart Foundation

  1/03/2015 → 28/02/2020

  Project: Research