Projects per year
- 1 - 50 out of 115 results
Search results
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Finished
Exploring how T and B cell populations regulate the development of HLA Antibodies, comparing pregnancy and transplantation, to inform novel strategies to help sensitised renal patients awaiting (re)transplantation
Lombardi, G. (Primary Investigator)
2/10/2024 → 30/04/2025
Project: Research
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Engineering third generation Tregs for the treatment of sensitised kidney transplant patients
Lombardi, G. (Primary Investigator), Dorling, A. (Co-Investigator), Sanchez Fueyo, A. (Co-Investigator) & Scotta, C. (Co-Investigator)
1/02/2023 → 20/08/2024
Project: Research
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BHF Centre Lombardi pump-prime
Lombardi, G. (Primary Investigator)
1/01/2023 → 30/09/2024
Project: Research
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Creating new opportunities for highly sensitised patients waiting for a kidney transplant
Lombardi, G. (Primary Investigator) & Scotta, C. (Co-Investigator)
1/01/2023 → 20/08/2024
Project: Research
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Engineering regulatory T cells (Tregs) to modulate kidney injury and prevent renal fibrosis
Lombardi, G. (Primary Investigator), Peng, Q. (Co-Investigator), Safinia, N. (Co-Investigator), Sanchez Fueyo, A. (Co-Investigator) & Sharpe, C. (Co-Investigator)
7/05/2022 → 31/07/2024
Project: Research
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Optimization of the potency, specificity and survival properties of engineered regulatory T cells to treat inflammatory liver diseases
Sanchez Fueyo, A. (Primary Investigator), Fruhwirth, G. (Co-Investigator), Lombardi, G. (Co-Investigator) & Safinia, N. (Co-Investigator)
1/12/2021 → 30/11/2024
Project: Research
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Generation of Liver-Immune Double Chimeric Humanised Mouse Models: A Platform for Simultaneous Assessment of Function and Immunogenicity of Liver-Specific Cellular Therapies
Lombardi, G. (Primary Investigator)
1/10/2021 → 20/02/2023
Project: Research
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CAR-Treg therapy in metabolic and inflammatory disorders: Targeting the Nrf2/HO-1 pathway
Safinia, N. (Primary Investigator) & Lombardi, G. (Co-Investigator)
1/11/2020 → 12/07/2022
Project: Research
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Regulatory T cells in Highly Sensitised Renal Patients to Improve Outcomes after HLA-Ab Incompatible Transplantation
Dorling, A. (Primary Investigator), Bunce, C. (Co-Investigator), Lombardi, G. (Co-Investigator), Sanchez Fueyo, A. (Co-Investigator) & Robinson, E. (Co-Investigator)
30/09/2020 → 29/05/2024
Project: Research
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Exploring the Links Between Regulatory T cell Populations and Development of HLA Antibodies in Renal Patients Awaiting Transplantation.
Dorling, A. (Primary Investigator), Basu, S. (Co-Investigator) & Lombardi, G. (Co-Investigator)
1/03/2020 → 28/02/2023
Project: Research
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INsTRuCT: INnovative Training in myeloid Regulatory Cell Therapy
Martinez-Llordella, M. (Primary Investigator) & Lombardi, G. (Co-Investigator)
1/01/2020 → 31/12/2023
Project: Research
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Production of expanded autologous regulatory T cells to treat patients with refractory aplastic anaemia in a phase I dose study
Mufti, G. (Primary Investigator), Lombardi, G. (Primary Investigator), Flach, C. (Primary Investigator) & Farzaneh, F. (Primary Investigator)
18/11/2019 → 31/01/2023
Project: Research
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Immunogenicity test platform - in vitro and in vivo
Lombardi, G. (Primary Investigator)
1/01/2019 → 31/12/2021
Project: Research
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Regulatory T cells in Highly Sensitised Renal Patients to Improve Outcomes after HLA-Antibody Incompatible Transplantation
Dorling, A. (Primary Investigator), Lombardi, G. (Co-Investigator) & Dudreuilh, C. (Co-Investigator)
1/10/2018 → 30/11/2022
Project: Research
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Targeting Nox2 to improve regulatory T cell function and immune tolerance in heart transplantation
Shah, A. (Primary Investigator), Cellone Trevelin, S. (Co-Investigator), Lombardi, G. (Co-Investigator), Ivetic, A. (Co-Investigator) & Lechler, R. (Co-Investigator)
10/08/2018 → 9/08/2021
Project: Research
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Creating new opportunities for highly sensitised patients waiting for a kidney transplant
Lombardi, G. (Primary Investigator) & Dorling, A. (Co-Investigator)
1/03/2018 → 31/05/2021
Project: Research
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Targeting recipient antigen-presenting cells with sialic acid-modified alloantigen to promote transplantation tolerance
Lombardi, G. (Primary Investigator), Lechler, R. (Co-Investigator) & Smyth, L. A. (Co-Investigator)
1/10/2017 → 30/09/2020
Project: Research
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Investigation of a novel cell therapy with regulatory T cells in the treatment of SLE
Scotta, C. (Primary Investigator), Lombardi, G. (Co-Investigator) & Robson, M. (Co-Investigator)
1/10/2017 → 30/09/2018
Project: Research
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NIHR Biomedical Research Centre. Funding for Financial Years 2017/18, 2018/19
Wolfe, C. (Primary Investigator), Parsons, M. (Primary Investigator), Gould, H. (Primary Investigator), Corrigan, C. (Primary Investigator), Greenough, A. (Primary Investigator), Peakman, M. (Primary Investigator), Vyse, T. (Primary Investigator), Antoniou, M. (Primary Investigator), Oakey, R. (Primary Investigator), McGrath, J. (Primary Investigator), Karagiannis, S. (Primary Investigator), Barker, J. (Primary Investigator), Flohr, C. (Primary Investigator), Tziotzios, C. (Primary Investigator), Whittaker, S. (Primary Investigator), Spector, T. (Primary Investigator), Watt, F. (Primary Investigator), Hayday, A. (Primary Investigator), Spencer, J. (Primary Investigator), Cope, A. (Primary Investigator), Malim, M. (Primary Investigator), Martin Serrano, J. (Primary Investigator), Edgeworth, J. (Primary Investigator), Cason, J. (Primary Investigator), Lord, G. (Primary Investigator), Dorling, A. (Primary Investigator), Sacks, S. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Lombardi, G. (Primary Investigator), Ostermann, M. (Primary Investigator), Shah, A. (Primary Investigator), Marber, M. (Primary Investigator), Mayr, M. (Primary Investigator), Chowienczyk, P. (Primary Investigator), Wells, C. (Primary Investigator), Grigoriadis, A. (Primary Investigator), Sawyer, E. (Primary Investigator), Maher, J. (Primary Investigator), Tribe, R. (Primary Investigator), Ilic, D. (Primary Investigator), Poston, L. (Primary Investigator), Rutherford, M. (Primary Investigator), Gee, T. (Primary Investigator), Blower, P. (Primary Investigator), Edwards, D. (Primary Investigator), Sharpe, P. (Primary Investigator), Streit, A. (Primary Investigator), Naglik, J. (Primary Investigator), Tavassoli, M. (Primary Investigator) & McNaughton, P. (Primary Investigator)
NIHR National Institute For Health & Care Research
1/04/2017 → 31/03/2022
Project: Research
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Use of Low-Dose IL-2 to expand endogenous regulatory T Cells and achieve transplantation tolerance
Sanchez Fueyo, A. (Primary Investigator), Douiri, A. (Co-Investigator), Lombardi, G. (Co-Investigator), Martinez-Llordella, M. (Co-Investigator) & Tree, T. (Co-Investigator)
15/02/2017 → 14/01/2021
Project: Research
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The TWO Study: A Phase II trial of regulatory T cells in renal transplantation - can we achieve sirolimus monotherapy?
Lombardi, G. (Primary Investigator)
1/02/2017 → 31/01/2022
Project: Research
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Defining the mechanisms underlying the role of regulatory T cells in the establishment of tolerance
Lombardi, G. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Douiri, A. (Co-Investigator), Lechler, R. (Co-Investigator) & Martinez-Llordella, M. (Co-Investigator)
9/01/2017 → 8/01/2022
Project: Research
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Thymus derived Tregs expanded in vitro as a treatment for paediatric heart transplant patients to prevent cardiac allograft vasculopathy.
Lombardi, G. (Primary Investigator), Botnar, R. (Co-Investigator), Lechler, R. (Co-Investigator) & Scotta, C. (Co-Investigator)
1/01/2017 → 31/12/2018
Project: Research
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In vivo analysis of Rho GTPase signalling in T-cell transendothelial migration
Ridley, A. (Primary Investigator) & Lombardi, G. (Co-Investigator)
14/10/2016 → 13/10/2017
Project: Research
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mTOR and the dark side of regulatory T cells: In search of a common mechanism underlying regulatory T cell dysfunction in immune-mediated inflammatory disease
Lombardi, G. (Primary Investigator)
1/10/2016 → 30/09/2018
Project: Research
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Investigation of a novel cell therapy with regulatory t cells in the treatment of Systemic Lupus Erythematosus
Scotta, C. (Primary Investigator), Lombardi, G. (Co-Investigator), Robson, M. (Co-Investigator) & Spencer, J. (Co-Investigator)
1/10/2016 → 30/09/2019
Project: Research
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Integrating imaging into immunotherapy - developing PET traceable CAR T-cells
Fruhwirth, G. (Primary Investigator), Lombardi, G. (Co-Investigator) & Maher, J. (Co-Investigator)
1/07/2016 → 14/09/2018
Project: Research
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Defining the mechanisms underlying the role of regulatory t cells in the establishment of tolerance
Lombardi, G. (Primary Investigator), Lechler, R. (Co-Investigator), Martinez-Llordella, M. (Co-Investigator), Rebollo-Mesa, I. (Co-Investigator) & Sanchez Fueyo, A. (Co-Investigator)
1/06/2016 → 31/05/2021
Project: Research
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Targeted Regulatory T Cell Therapy for Inflammatory Bowel Disease
Lord, G. (Primary Investigator), Lombardi, G. (Co-Investigator), Powell, N. (Co-Investigator) & Prevost, T. (Co-Investigator)
1/05/2016 → 1/08/2019
Project: Research
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Multilayered nanocoatings for depot delivery of therapeutic agents to islet grafts: strategies for improving outcome of islet transplantation
Zhi, L. (Primary Investigator), Jones, P. (Co-Investigator) & Lombardi, G. (Co-Investigator)
1/02/2016 → 31/01/2019
Project: Research
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Manipulating the molecular responses of fibrocytes to prevent intimal hyperplasia.
Dorling, A. (Primary Investigator), Chen, D. (Co-Investigator) & Lombardi, G. (Co-Investigator)
1/01/2016 → 31/12/2018
Project: Research
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Preclinical assessment of targeting DCs directly in vivo to prevent human islet transplant rejection as a cure for Type 1 diabetes
Lombardi, G. (Primary Investigator), Huang, G. (Co-Investigator), Jones, P. (Co-Investigator), Lechler, R. (Co-Investigator) & Xiao, F. (Co-Investigator)
1/01/2016 → 31/12/2018
Project: Research
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MICA: Targeted Regulatory T Cell Therapy for Inflammatory Bowel Disease
Lord, G. (Primary Investigator), Lombardi, G. (Co-Investigator), Powell, N. (Co-Investigator) & Prevost, T. (Co-Investigator)
1/01/2016 → 31/03/2024
Project: Research
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Preclinical assessment of targeting DCs directly in vivo to prevent human islet transplant rejection as a cure for Type 1 diabetes
Lombardi, G. (Primary Investigator), Huang, G. (Co-Investigator), Jones, P. (Co-Investigator), Lechler, R. (Co-Investigator) & Xiao, F. (Co-Investigator)
1/01/2016 → 31/12/2018
Project: Research
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Preclinical assessment of targeting DCs directly in vivo to prevent human islettransplant rejection as a cure for Type 1 diabetes
Lombardi, G. (Primary Investigator), Huang, G. (Co-Investigator), Jones, P. (Co-Investigator), Lechler, R. (Co-Investigator) & Xiao, F. (Co-Investigator)
1/01/2016 → 31/12/2018
Project: Research
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NIHR Blood and Transplant Unit (Organ Donation and Transplantation)
Dorling, A. (Primary Investigator), Dazzi, F. (Co-Investigator), Hernandez Fuentes, M. (Co-Investigator), Lombardi, G. (Co-Investigator), Sacks, S. (Co-Investigator) & Smith, R. (Co-Investigator)
1/10/2015 → 30/09/2020
Project: Research
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Investigation of a novel cell therapy with regulatory T cells in systemic Lupus erythematosus
Lombardi, G. (Primary Investigator)
1/10/2015 → 30/09/2017
Project: Research
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Intestinal Graft Versus Host Disease, a new diagnostic and therapeutic paradigm
Powell, N. (Primary Investigator) & Lombardi, G. (Co-Investigator)
1/09/2015 → 31/08/2018
Project: Research
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Integrating imaging into Immunotherapy - Developing in vivo traceable CAR T-cells
Fruhwirth, G. (Primary Investigator), Lombardi, G. (Co-Investigator) & Maher, J. (Co-Investigator)
1/08/2015 → 31/01/2017
Project: Research
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Identifying new targets for treating gut damage in graft versus host disease
Powell, N. (Primary Investigator) & Lombardi, G. (Co-Investigator)
1/05/2015 → 30/04/2018
Project: Research
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Regulatory T cell derived Exosomes: possible therapeutic and diagnostic tools in transplantation
Lombardi, G. (Primary Investigator) & Smyth, L. (Primary Investigator)
1/04/2015 → 31/03/2016
Project: Research
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Integrating imaging into Immunotherapy - Developing in vivo traceable CAR T-cells
Fruhwirth, G. (Primary Investigator), Lombardi, G. (Co-Investigator) & Maher, J. (Co-Investigator)
1/04/2015 → 7/07/2016
Project: Research
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EMI-TB - Eliciting Mucosal Immunity to Tuberculosis
Ivanyi, J. (Primary Investigator), Lombardi, G. (Co-Investigator) & Naglik, J. (Co-Investigator)
1/01/2015 → 31/12/2018
Project: Research
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Regulatory T-cell therapy for Orthotopic Heart Transplantation in Children
Botnar, R. (Primary Investigator), Hussain, M. (Primary Investigator), Greil, G. (Co-Investigator) & Lombardi, G. (Co-Investigator)
1/01/2015 → 2/08/2016
Project: Research
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Manipulating protease activated receptor (PAR) signalling on mononuclear cells to prevent intimal hyperplasia / chronic fibrosis AND promote regenerative repair
Dorling, A. (Primary Investigator), Chen, D. (Co-Investigator), Lombardi, G. (Co-Investigator), Smith, R. (Co-Investigator) & Zhou, W. (Co-Investigator)
1/10/2014 → 30/09/2019
Project: Research
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In vitro manipulation of defective TREGS as therapy for systemic lupus erythematosus
Lombardi, G. (Primary Investigator) & Scotta, C. (Co-Investigator)
1/09/2014 → 30/09/2015
Project: Research
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Overcoming immunological barriers to regenerative medicine
Watt, F. (Primary Investigator), Dazzi, F. (Co-Investigator), Geissmann, F. (Co-Investigator), Lombardi, G. (Co-Investigator) & Sacks, S. (Co-Investigator)
1/04/2014 → 31/03/2018
Project: Research
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In vitro manipulation of defective tregs as therapy for systemic Lupus erythematosus
Lombardi, G. (Primary Investigator)
1/03/2014 → 28/02/2015
Project: Research
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Investigating Regulatory T Cell-Based Therapy In Systemic Lupus Erythematosus
Lombardi, G. (Primary Investigator)
1/02/2014 → 31/01/2017
Project: Research
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BASEMENT MEMBRANE BASED BIOMATERIALS AND SCAFFOLDS - BASESCAFF
Lombardi, G. (Primary Investigator)
1/01/2014 → 30/06/2017
Project: Research