Research output per year
Research output per year
Personal profile
Research interests
<p>Regulation of redox signaling and Nrf2/antioxidant response element mediated gene expression in vascular endothelial and smooth muscle cells; influence of epigenetics on fetal programing of endothelial dysfunction in offspring born to mothers with pre-eclampsia and gestational diabetes.</p>
Research interests (short)
Impaired redox signalling in endothelial and smooth muscle in pre-eclampsia, diabetes and atherosclerosis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Physiology, Master in Science, UCL University College London
1 Sept 1973 → 30 Aug 1974
Award Date: 1 Jul 1974
Zoology, Bachelor of Science, George Washington University
1 Sept 1969 → 1 Jun 1973
Award Date: 3 Sept 1973
Physiology, Doctor of Philosophy, UCL University College London
1 Oct 1974 → 30 Sept 1977
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Control of Redox Homeostasis by Short-Chain Fatty Acids: Implications for the Prevention and Treatment of Breast Cancer
González-Bosch, C., Zunszain, P. A. & Mann, G. E., Mar 2023, In: Pathogens. 12, 3, 486.Research output: Contribution to journal › Review article › peer-review
Open Access -
Introduction to Special Issue on “Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases”
Cuadrado, A., Dinkova-Kostova, A. T. & Mann, G. E., 1 Feb 2023, In: Free Radical Biology and Medicine. 195, p. 258-260 3 p.Research output: Contribution to journal › Editorial › peer-review
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Redox and metal profiles in human coronary endothelial and smooth muscle cells under hyperoxia, physiological normoxia and hypoxia: Effects of NRF2 signaling on intracellular zinc
Smith, M. J., Yang, F., Griffiths, A., Morrell, A., Chapple, S. J., Siow, R. C. M., Stewart, T., Maret, W. & Mann, G. E., Jun 2023, In: Redox Biology. 62, 102712.Research output: Contribution to journal › Article › peer-review
Open Access -
Stress Activated MAP Kinases and Cyclin-Dependent Kinase 5 Mediate Nuclear Translocation of Nrf2 via Hsp90α-Pin1-Dynein Motor Transport Machinery
Ishii, T., Warabi, E. & Mann, G. E., Feb 2023, In: Antioxidants. 12, 2, 274.Research output: Contribution to journal › Review article › peer-review
Open Access -
Vascular protection afforded by zinc supplementation in human coronary artery smooth muscle cells mediated by NRF2 signaling under hypoxia/reoxygenation: Zinc supplementation protects against hypoxia/reoxygenation
Yang, F., Smith, M., Griffiths, A., Morrell, A., Chapple, S., Siow, R., Stewart, T., Maret, W. & Mann, G., 30 Jun 2023, In: Redox Biology.Research output: Contribution to journal › Article › peer-review
Projects
- 63 Finished
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The role of LOC105 in endothelial cell dysfunction in diabetes mellitus
Zampetaki, A., Shah, A. & Mann, G.
1/12/2019 → 30/11/2022
Project: Research
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Does NO-dependent AMPK activity prevent pathological vascular remodelling?
3/07/2017 → 2/07/2020
Project: Research
Activities
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international research symposia in Leicester
Giovanni Mann (Organiser)
2001 → …Activity: Participating in or organising an event › Participation in conference
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international research symposia in Seville
Giovanni Mann (Organiser)
2001 → …Activity: Participating in or organising an event › Participation in conference
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international research symposia in Budapest
Giovanni Mann (Organiser)
2001 → …Activity: Participating in or organising an event › Participation in conference
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international research symposia in Tübingen
Giovanni Mann (Organiser)
2001 → …Activity: Participating in or organising an event › Participation in conference
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14 international/national symposia
Giovanni Mann (Keynote/plenary speaker)
2001 → …Activity: Participating in or organising an event › Participation in conference