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Graeme Hewitt

Dr

 https://orcid.org/0000-0003-2614-6932
    • 2707
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    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    • SDG 3 - Good Health and Well-being

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    Collaborations and top research areas from the last five years

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    • RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks

      Zhao, S., Cordes, J., Caban, K. M., Götz, M. J., Mackens-Kiani, T., Veltri, A. J., Sinha, N. K., Weickert, P., Kaya, S., Hewitt, G., Nedialkova, D. D., Fröhlich, T., Beckmann, R., Buskirk, A. R., Green, R. & Stingele, J., 2 Nov 2023, (E-pub ahead of print) In: MOLECULAR CELL.

      Research output: Contribution to journal › Article › peer-review

    • H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ

      Bayley, R., Borel, V., Moss, R. J., Sweatman, E., Ruis, P., Ormrod, A., Goula, A., Mottram, R. M. A., Stanage, T., Hewitt, G., Saponaro, M., Stewart, G. S., Boulton, S. J. & Higgs, M. R., 19 May 2022, In: MOLECULAR CELL. 82, 10, p. 1924-1939.e10

      Research output: Contribution to journal › Article › peer-review

      Open Access
      7 Citations (Scopus)

    • POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells

      Belan, O., Sebald, M., Adamowicz, M., Anand, R., Vancevska, A., Neves, J., Grinkevich, V., Hewitt, G., Segura-Bayona, S., Bellelli, R., Robinson, H. M. R., Higgins, G. S., Smith, G. C. M., West, S. C., Rueda, D. S. & Boulton, S. J., 15 Dec 2022, In: MOLECULAR CELL. 82, 24, p. 4664-4680.e9

      Research output: Contribution to journal › Article › peer-review

      Open Access
      16 Citations (Scopus)

    • Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

      Hewitt, G., Borel, V., Segura-Bayona, S., Takaki, T., Ruis, P., Bellelli, R., Lehmann, L. C., Sommerova, L., Vancevska, A., Tomas-Loba, A., Zhu, K., Cooper, C., Fugger, K., Patel, H., Goldstone, R., Schneider-Luftman, D., Herbert, E., Stamp, G., Brough, R., Pettitt, S., & 7 othersLord, C. J., West, S. C., Ahel, I., Ahel, D., Chapman, J. R., Deindl, S. & Boulton, S. J., 18 Feb 2021, In: MOLECULAR CELL. 81, 4, p. 767-783.e11

      Research output: Contribution to journal › Article › peer-review

      Open Access
      58 Citations (Scopus)

    • mTORC1 activity is supported by spatial association with focal adhesions

      Rabanal-Ruiz, Y., Byron, A., Wirth, A., Madsen, R., Sedlackova, L., Hewitt, G., Nelson, G., Stingele, J., Wills, J. C., Zhang, T., Zeug, A., Fässler, R., Vanhaesebroeck, B., Maddocks, O. D. K., Ponimaskin, E., Carroll, B. & Korolchuk, V. I., Feb 2021, In: Journal of Cell Biology. 220, 5, e202004010.

      Research output: Contribution to journal › Article › peer-review

      Open Access
      28 Citations (Scopus)
    View all 20 research outputs