Research output per year
Research output per year
- 33 results
Search results
-
2025
Obstetric and gynaecological features in females carrying variants in the skeletal muscle ryanodine receptor type 1 (RYR1) gene: a questionnaire study.
Mistry, A., Saldanha, G., Bersselaar , L. R. V. D., Knock, G., Goldberg, M. F., Vanegas, M. I., Fernandez-Garcia, M. A., Treves, S., Voermans, N. C., Tribe, R. & Jungbluth, H., 20 Feb 2025, In: Neuromuscular Disorders. 49, 105335.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Sphingosine-1-phosphate induces airway smooth muscle hyperresponsiveness and proliferation
Maguire, T. J. A., Yung, S., Ortiz-Zapater, E., Kayode, O. S., Till, S., Corrigan, C., Siew, L. Q. C., Knock, G. A. & Woszczek, G., Nov 2023, In: Journal of Allergy and Clinical Immunology. 152, 5, p. 1131-1140.e6Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
2021
Signalling mechanisms in the cardiovascular protective effects of estrogen: With a focus on rapid/membrane signalling.
Niță, A. R., Knock, G. A. & Heads, R. J., Jan 2021, In: Current Research in Physiology. 4, p. 103-118 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access37 Citations (Scopus) -
2019
NADPH oxidase in the vasculature: Expression, regulation and signalling pathways; role in normal cardiovascular physiology and its dysregulation in hypertension
Knock, G. A., Dec 2019, In: Free Radical Biology and Medicine. 145, p. 385-427 43 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile85 Citations (Scopus)621 Downloads (Pure) -
2018
Role of reactive oxygen species and sulfide-quinone oxoreductase in hydrogen sulfide-induced contraction of rat pulmonary arteries
Prieto-Lloret, J., Snetkov, V., Shaifta, Y. M., Docio, I., Connolly, M., MacKay, C. E., Knock, G. A., Ward, J. P. T. & Aaronson, P. I., Apr 2018, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 314, 4, p. L670-L685Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)291 Downloads (Pure) -
Transforming growth factor-β enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1
Shaifta, Y., MacKay, C. E., Irechukwu, N. I., O'Brien, K., Wright, D. B., Ward, J. P. T. & Knock, G. A., 1 Jan 2018, In: The Journal of Physiology. 595, 1, p. 47-66Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)234 Downloads (Pure) -
2017
ROS-dependent activation of RhoA/Rho-kinase in pulmonary artery: Role of Src-family kinases and ARHGEF1
MacKay, C. E., Shaifta, Y., Snetkov, V. V., Francois, A. A., Ward, J. P. T. & Knock, G. A., Sept 2017, In: Free Radical Biology and Medicine. 110, p. 316-331Research output: Contribution to journal › Article › peer-review
Open AccessFile44 Citations (Scopus)396 Downloads (Pure) -
2015
Control of vascular smooth muscle function by Src-family kinases and reactive oxygen species in health and disease
MacKay, C. & Knock, G., 1 Sept 2015, In: The Journal of Physiology. 593, 17, p. 3815-3828 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile68 Citations (Scopus)87 Downloads (Pure) -
Divergent modulation of Rhokinase and Ca2+ influx pathways by Src family kinases and focal adhesion kinase in airway smooth muscle
Shaifta, Y. M., Irechukwu, N. I., Prieto-Lloret, J., MacKay, C. E., Marchon, K., Ward, J. P. T. & Knock, G. A., 1 Nov 2015, In: Br J Pharmacol. 172, 22, p. 5265-5280Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)309 Downloads (Pure) -
Sphingosylphosphorylcholine potentiates vasoreactivity and voltage-gated Ca2+ entry via NOX1 and reactive oxygen species
Shaifta, Y., Snetkov, V. A., Prieto-Lloret, J., Smirnov, S. V., Knock, G., Aaronson, P. & Ward, J., 2015, In: Cardiovascular Research. 106, p. 121–130Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)217 Downloads (Pure) -
2011
Redox Regulation of Protein Kinases as a Modulator of Vascular Function
Knock, G. A. & Ward, J. P. T., 15 Sept 2011, In: ANTIOXIDANTS AND REDOX SIGNALING. 15, 6, p. 1531 - 1547 17 p.Research output: Contribution to journal › Literature review › peer-review
92 Citations (Scopus) -
Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways
Snetkov, V. A., Smirnov, S. V., Kua, J., Aaronson, P. I., Ward, J. P. T. & Knock, G. A., 1 Jan 2011, In: Cardiovascular Research. 89, 1, p. 214 - 224 11 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
2009
Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca2+ sensitization
Knock, G. A., Snetkov, V. A., Shaifta, Y., Connolly, M., Drndarslci, S., Noah, A., Pourlrlahram, G. E., Becker, S., Aaronson, P. I. & Ward, J. P. T., 1 Mar 2009, In: Free Radical Biology and Medicine. 46, 5, p. 633 - 642 10 p.Research output: Contribution to journal › Article › peer-review
92 Citations (Scopus) -
2008
Constriction of pulmonary artery by peroxide: role of Ca2+ release and PKC
Pourmahram, G. E., Snetkov, V. A., Shaifta, Y., Drndarski, S., Knock, G. A., Aaronson, P. I. & Ward, J. P. T., 15 Nov 2008, In: Free Radical Biology and Medicine. 45, 10, p. 1468 - 1476 9 p.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
Interaction Between Src-Family Kinases and Rho-Kinase in Agonist-Induced Ca2+-Sensitization of Rat Pulmonary Artery
Knock, G. A., Shaifta, Y., Snetkov, V. A., Vowles, B., Drndarski, S., Ward, J. P. T. & Aaronson, P. I., Feb 2008, In: Cardiovascular Research. 77, 3, p. 570 - 579 10 p.Research output: Contribution to journal › Article › peer-review
47 Citations (Scopus) -
Low concentrations of sphingosylphosphorylcholine enhance pulmonary artery vasoreactivity - The role of protein kinase C delta and Ca2+ entry
Snetkov, V. A., Thomas, G. D., Teague, B., Leach, R. M., Shaifta, Y., Knock, G. A., Aaronson, P. I. & Ward, J. P. T., Feb 2008, In: Hypertension. 51, 2, p. 239 - 245 7 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery
Knock, G. A., Snetkov, V. A., Shaifta, Y., Drndarski, S., Ward, J. P. T. & Aaronson, P. I., Dec 2008, In: Cardiovascular Research. 80, 3, p. 453 - 462 10 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
2007
Effect of ceramide on the contractility of pregnant rat uterus
Srivastava, A., Gupta, P. K., Knock, G. A., Aaronson, P. I., Mishra, S. K. & Prakash, V. R., 12 Jul 2007, In: European Journal of Pharmacology. 567, 1-2, p. 159 - 165 7 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
2006
Dietary soy modulates endothelium-dependent relaxation in aged male rats: Increased agonist-induced endothelium-derived hyperpolarising factor and basal nitric oxide activity
Knock, G. A., Mahn, K., Mann, G. E., Ward, J. P. T. & Aaronson, P. I., 1 Sept 2006, In: Free Radical Biology and Medicine. 41, 5, p. 731 - 739 9 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
Hypoxic pulmonary vasoconstriction: mechanisms and controversies
Aaronson, P., Robertson, T., Knock, G., Becker, S., Lewis, T. & Ward, J., 1 Jan 2006, In: The Journal of Physiology. 571, 1, p. 53-58 6 p.Research output: Contribution to journal › Article › peer-review
129 Citations (Scopus) -
2005
Euhydric hypercapnia increases vasoreactivity of rat pulmonary arteries via HCO3- transport and depolarisation
Vankova, M., Snetkov, V. A., Knock, G. A., Aaronson, P. L. & Ward, J. P. T., 1 Feb 2005, In: Cardiovascular Research. 65, 2, p. 505 - 512 8 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Modulation of PGF(2 alpha)- and hypoxia-induced contraction of rat intrapulmonary artery by p38 MAPK inhibition: a nitric oxide-dependent mechanism
Knock, G. A., De Silva, A. S., Snetkov, V. A., Siow, R., Thomas, G. D., Shiraishi, M., Walsh, M. P., Ward, J. P. T. & Aaronson, P. I., Dec 2005, In: AMERICAN JOURNAL OF PHYSIOLOGY: LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 289, 6, p. L1039 - L1048Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
2004
Differential properties of the EDHF-mediated relaxations to propionate and acetylcholine in rat mesenteric resistance arteries
Teague, B. R., Knock, G. A. & Aaronson, P. I., 2004, In: Faseb Journal. 18, 5, p. A982 - A982Research output: Contribution to journal › Meeting abstract
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PGF(2 alpha)-induced contraction and increased intracellular calcium in small pulmonary arteries of the rat
Baxter, L. M., Snetkov, V. A., Aaronson, P. I., Ward, J. P. T. & Knock, G. A., 2004, In: Faseb Journal. 18, 4, p. A595 - A595Research output: Contribution to journal › Meeting abstract
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Protein kinases in vascular smooth muscle tone - role in the pulmonary vasculature and hypoxic pulmonary vasoconstriction
Ward, J. P. T., Knock, G. A., Snetkov, V. A. & Aaronson, P. I., Dec 2004, In: Pharmacology and Therapeutics. 104, 3, p. 207 - 231 25 p.Research output: Contribution to journal › Literature review › peer-review
72 Citations (Scopus) -
Role of pre-tone in hypoxic vasoconstriction of isolated rat pulmonary artery
Knock, G. A., Aaronson, P. I. & Ward, J. P. J., 2004, In: Faseb Journal. 18, 4, p. A595 - A595Research output: Contribution to journal › Meeting abstract
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2003
Capacitative calcium entry as a pulmonary specific vasoconstrictor mechanism in small muscular arteries of the rat
Snetkov, V. A., Aaronson, P. I., Ward, J. P. T., Knock, G. A. & Robertson, T. P., Sept 2003, In: British Journal of Pharmacology. 140, 1, p. 97 - 106 10 p.Research output: Contribution to journal › Article › peer-review
81 Citations (Scopus) -
2002
Priopionate-induced relaxation in rat mesenteric arteries: a role for endothelium-derived hyperpolarising factor
Knock, G., Psaroudakis, D., Abbot, S. & Aaronson, P. I., 1 Feb 2002, In: The Journal of Physiology. 538, 3, p. 879 - 890 12 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
2001
Mechanisms of propionate-induced relaxation in rat mesenteric arteries: a role for EDHF
Knock, G., Psaroudakis, D., Abbott, S. & Aaronson, P., 2001, In: The Journal of Physiology. 536, p. 113P - 114PResearch output: Contribution to journal › Meeting abstract
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Modulation of potassium current characteristics in human myometrial smooth muscle by 17 beta-estradiol and progesterone
Knock, G. A., Tribe, R. M., Hassoni, A. A. & Aaronson, P. I., 2001, In: Biology of Reproduction. 64, 5, p. 1526 - 1534 9 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
Modulation of potassium current characteristics in human myometrial smooth muscle by 17 beta oestradiol and progesterone
Knock, G. A., Tribe, R. M., Hassoni, A. A. & Aaronson, P., 2001, In: The Journal of Physiology. p. 87 - 87 1 p.Research output: Contribution to journal › Meeting abstract
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2000
Mechanism of effect of extracellular pH on L-type Ca2+ channel currents in human mesenteric arterial cells
Smirnov, S. V., Knock, G. A., Belevych, A. E. & Aaronson, P. I., 2000, In: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 279, 1, p. H76 - H85Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
Modulation or L-type Ca2+ channel currents by extracellular pH in human vasculature
Smirnov, S. V., Knock, G. A., Belevych, A. E. & Aaronson, P. I., 2000, In: Biophysical Journal. 78, 1, p. 457A - 457AResearch output: Contribution to journal › Meeting abstract