Research output per year
Research output per year
Personal profile
Research interests
Molecular and cellular imaging of ischemia reperfusion injury, hypoxia, transplant rejection and infectious disease; using radiolabeled small molecules, proteins, immune cells and stem cells.
Dr Mullen proposed the molecular structure of the extracellular domain of toll-like receptors, and has taken novel malaria vaccines from bench to bedside. This included cGMP production, preclinical evaluation, USFDA regulatory approval and coordination of both US and African field trials of candidate vaccines in adults and paediatric populations.
Research interests (short)
In vivo imaging of complement activation, hypoxia, immune and stem cells.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Technetium and Rhenium Thioether Complexes , University of Kent
Award Date: 1 Jan 1998
Bachelor of Science, University of Kent
Award Date: 1 Jan 1995
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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An indium-111-labelled membrane-targeted peptide for cell tracking with radionuclide imaging
Prueller, J., Pham, T., Blower, J., Charoenphun, P., Volpe, A., Sunassee, K., Mullen, G., Blower, P., Smith, R. & Ma, M., 19 Oct 2022, (E-pub ahead of print) In: RSC Chemical Biology. p. 65-73Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)105 Downloads (Pure) -
Correlation of hypoxia PET tracer uptake with hypoxic radioresistance in cancer cells: PET biomarkers of resistance to stereotactic radiation therapy?
Chia, K., Paul, R. L., Weeks, A. J., Naeem, M., Mullen, G. E. D., Landau, D. & Blower, P. J., 1 Jul 2022, In: Nuclear Medicine and Biology. 110-111, p. 10-17 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
HER2 mediates PSMA/mGluR1-driven resistance to the DS-7423 dual 2 PI3K/mTOR inhibitor in PTEN wild-type prostate cancer models: PTEN-wt PCa overcomes PI3K inhibition via mGluR1 signaling
Gómez, V., Galazi, M., Weitsman, G., Monypenny of Pitmilly, J., Al-Salemee, F., Barber, P., Ng, K., Beatson, R., Szokol, B., Orfi, L., Mullen, G., Vanhaesebroeck, B., Chowdhury, S., Leung, H. Y. & Ng, T., 19 Jan 2022, (Accepted/In press) In: MOLECULAR CANCER THERAPEUTICS.Research output: Contribution to journal › Article › peer-review
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Optimal His-Tag Design for Efficient [99mTc(CO)3]+and [188Re(CO)3]+Labeling of Proteins for Molecular Imaging and Radionuclide Therapy by Analysis of Peptide Arrays
Williams, J. D., Kampmeier, F., Badar, A., Howland, K., Cooper, M. S., Mullen, G. E. D. & Blower, P. J., 2020, (Accepted/In press) In: Bioconjugate Chemistry.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Author Correction: Non-Invasive whole-body detection of complement activation using radionuclide imaging in a mouse model of myocardial ischaemia-reperfusion injury
Sharif-Paghaleh, E., Yap, M. L., Puhl, S. L., Badar, A., Torres, J. B., Chuamsaamarkkee, K., Kampmeier, F., Smith, R. A., Clark, J., Blower, P. J., Sacks, S. & Mullen, G. E., 13 Mar 2018, In: Scientific Reports. 8, 1, p. 4687 1 p.Research output: Contribution to journal › Article › peer-review
Open Access
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Chelators for short half life radionuclides for PET imaging and radionuclide therapy
Blower, P. (Primary Investigator) & Mullen, G. (Co-Investigator)
Project: Research
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Zirconium-89 cell labelling platforms for in vivo cell tracking with PET
Ma, M. (Primary Investigator), Mullen, G. (Co-Investigator) & Terry, S. (Co-Investigator)
1/10/2016 → 31/07/2018
Project: Research
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Development of S100A8/A9-based Radionuclide Imaging to probe Exosome release andimmunomodulation in colorectal cancer patients (DES1REx)
Ng, T. (Primary Investigator), Blower, P. (Co-Investigator), Mullen, G. (Co-Investigator) & Schaeffter, T. (Co-Investigator)
1/11/2015 → 31/12/2019
Project: Research
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A prostate-specific PET tracer to evaluate therapy response in prostate cancer
Cook, G. (Primary Investigator), Weeks, A. (Primary Investigator), Ballinger, J. (Co-Investigator), Blower, P. (Co-Investigator), Goh, V. (Co-Investigator) & Mullen, G. (Co-Investigator)
1/07/2015 → 30/06/2016
Project: Research
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Development, application and dissemination of novel in vivo cell tracking technologies to support 3Rs principles
Blower, P. (Primary Investigator), Fruhwirth, G. (Co-Investigator), Mullen, G. (Co-Investigator), Page, C. (Co-Investigator), Thanou, M. (Co-Investigator) & academic, A. (Co-Investigator)
1/06/2014 → 31/05/2016
Project: Research
Activities
- 1 Types of Public engagement and outreach - Media article or participation
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Scan tracks the movement of white blood cells to show if your asthma drugs work
Mullen, G. (Interviewee)
8 Dec 2014Activity: Other › Types of Public engagement and outreach - Media article or participation