Greg Woszczek

Greg Woszczek

Dr

  • Phone020 7188 0597
  • SE1 9RT

    United Kingdom

  • 1173
    Citations

Personal profile

Research interests

Our research focuses on characterisation of G-protein coupled receptors (GPCRs) (the largest family of transmembrane signalling molecules) and their role in immune reactions leading to chronic inflammatory diseases, such as bronchial asthma and allergic diseases. Although, GPCRs are targets for more than 30% of all approved drugs, the expression and function of many of those receptors are incompletely characterized, and many remain orphans (without known ligands). The last years have seen remarkable advances in structural and functional biology of GPCRs that await now for translational medicine research. The understanding of GPCR responsiveness to lipid mediators such as leukotrienes, prostaglandins, lipoxins and lysophospholipids and their role in pathophysiology of asthma and allergic diseases is still based on data obtained long time ago and often does not agree with current discoveries. Newly developed molecular and cellular biology methods allow us to re-evaluate tissue and cell type specific expression, signalling and function of GPCRs and to redefine their role in processes leading to airway inflammation, bronchoconstriction, hyperresponsiveness and airway remodelling. A better understanding of GPCR biology may lead to development of new therapies for asthma and allergy.

Research interests (short)

G-protein coupled receptors in immune response and respiratory diseases.

Research interests

Editorial activity

Associate Editor – BMC Immunology (2012 - )

Editorial Board Member - Inflammation & Allergy – Drug Targets (2013 - )

Research interests

Research organisations

Board member- Immunology Section, European Academy of Allergy and Clinical Immunology (2013-2015)(2015-2017)

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Philosophy, Genetic predisposition for differential organ manifestation of atopic diseases, Medical University of Lodz

Award Date: 1 Jan 2000

Doctor of Medicine, Medical University of Lodz

Award Date: 1 Jan 1993

External positions

Principal Investigator, Asthma UK Centre in Allergic Mechanisms of Asthma

2009 → …

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