King's College London

Research portal

Dr Hugues de Lavallade

  1. Third-dose SARS-CoV-2 mRNA vaccine increases Omicron variant neutralisation in patients with chronic myeloid disorders

    Harrington, P., Kurshan, A., Delord, M., Lechmere, T., Sheikh, A., Saunders, J., Saha, C., Dillon, R., Woodley, C., Asirvatham, S., Curto-Garcia, N., O'Sullivan, J., Kordasti, S., Radia, D. H., McLornan, D. P., Malim, M. H., Harrison, C. N., Doores, K. J. & de Lavallade, H., 9 Sep 2022, (E-pub ahead of print) In: Blood Advances.

    Research output: Contribution to journalArticlepeer-review

  2. Chronic myeloid leukaemia patients at diagnosis and resistant to tyrosine kinase inhibitor therapy display exhausted T-cell phenotype

    Harrington, P., Dillon, R., Radia, D., McLornan, D., Woodley, C., Asirvatham, S., Raj, K., Curto-Garcia, N., Saunders, J., Kordasti, S., Harrison, C. & de Lavallade, H., Sep 2022, In: British Journal of Haematology. 198, 6, p. 1011-1015 5 p.

    Research output: Contribution to journalArticlepeer-review

  3. Single dose of BNT162b2 mRNA vaccine against SARS-CoV-2 induces high frequency of neutralising antibody and polyfunctional T-cell responses in patients with myeloproliferative neoplasms

    Harrington, P., de Lavallade, H., Doores, K. J., O'Reilly, A., Seow, J., Graham, C., Lechmere, T., Radia, D., Dillon, R., Shanmugharaj, Y., Espehana, A., Woodley, C., Saunders, J., Curto-Garcia, N., O'Sullivan, J., Raj, K., Kordasti, S., Malim, M. H., Harrison, C. N. & McLornan, D. P., Dec 2021, In: Leukemia. 35, 12, p. 3573-3577 5 p.

    Research output: Contribution to journalArticlepeer-review

  4. Repeated vaccination against SARS-CoV-2 elicits robust polyfunctional T cell response in allogeneic stem cell transplantation recipients

    Harrington, P., Doores, K. J., Saha, C., Saunders, J., Child, F., Dillon, R., Saglam, S., Raj, K., McLornan, D., Avenoso, D., Kordasti, S., O'Reilly, A., Espehana, A., Lechmere, T., Khan, H., Malim, M. H., Harrison, C., Mehra, V. & de Lavallade, H., 8 Nov 2021, In: CANCER CELL. 39, 11, p. 1448-1449 2 p.

    Research output: Contribution to journalLetterpeer-review

  5. Single dose of BNT162b2 mRNA vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) induces neutralising antibody and polyfunctional T-cell responses in patients with chronic myeloid leukaemia

    Harrington, P., Doores, K. J., Radia, D., O'Reilly, A., Lam, H. P. J., Seow, J., Graham, C., Lechmere, T., McLornan, D., Dillon, R., Shanmugharaj, Y., Espehana, A., Woodley, C., Saunders, J., Curto-Garcia, N., O'Sullivan, J., Raj, K., Kordasti, S., Malim, M. H., Harrison, C., & 1 othersde Lavallade, H., Sep 2021, In: British Journal of Haematology. 194, 6, p. 999-1006 8 p.

    Research output: Contribution to journalArticlepeer-review

  6. Large Scale Internet-based Survey of Patients With a Myeloproliferative Neoplasm: Opinions and Experiences Regarding SARS-CoV-2 (COVID-19) Vaccination Strategies in 2021

    Saunders, J., Curto-Garcia, N., Sriskandarajah, P., O'Sullivan, J., Woodley, C., Asirvatham, S., Campbell-Drew, M., Mathias, J., Ellis, T., Baker, N., Radia, D. H., Ali, S., Kordasti, S., Harrington, P., de Lavallade, H., McLornan, D. P. & Harrison, C. N., Jul 2021

    Research output: Other contribution

  7. Low-dose Splenic Irradiation in Conjunction With Ruxolitinib to Provide Symptomatic Relief in Heavily Treated, Advanced Stage Myelofibrosis: A Case Series From a UK Tertiary Referral Center

    Khan, A., Woodley, C., Radia, D., Mikhaeel, G. N., Brady, J., Garcia, N. C., Harrington, P., O'Sullivan, J., Kordasti, S., Francis, Y., Asirvatham, S., Ali, S., Sriskandarajah, P., Saunders, J., de Lavallade, H., McLornan, D. P. & Harrison, C. N., Jul 2021, In: HemaSphere. 5, 7, e611.

    Research output: Contribution to journalArticlepeer-review

  8. Immunological effects of ponatinib therapy in patients with chronic myeloid leukaemia

    Harrington, P., Radia, D., Lim, M., Dillon, R., Kordasti, S., Rezvani, K., Harrison, C. & de Lavallade, H., Apr 2020, In: British Journal of Haematology. 189, p. 72-73

    Research output: Contribution to journalMeeting Abstractpeer-review

  9. Epstein-Barr Virus and Monoclonal Gammopathy of Clinical Significance in Autologous Stem Cell Transplantation for Multiple Sclerosis

    Mehra, V., Rhone, E., Widya, S., Zuckerman, M., Potter, V., Raj, K., Kulasekararaj, A. G., McLornan, D. P., de Lavallade, H., Benson-Quarm, N., Lim, C., Ware, S., Sudhanva, M., Malik, O., Nicholas, R., Muraro, P. A., Marsh, J., Mufti, G. J., Silber, E., Pagliuca, A., & 1 othersKazmi, M., 30 Oct 2019, In: Clinical Infectious Diseases. 69, 10, p. 1757-1763 7 p.

    Research output: Contribution to journalArticlepeer-review

  10. Comparative analysis of melphalan versus busulphan T-cell deplete conditioning using alemtuzumab in unrelated donor stem cell transplantation for acute myeloid leukaemia

    Sellar, R. S., Mehra, V., Fox, T. A., Grigg, A., Kulasekararaj, A., Sarma, A., de Lavallade, H., McLornan, D., Raj, K., Mufti, G. J., Pagliuca, A., Mackinnon, S., Chakraverty, R., Fielding, A. K., Carpenter, B., Kottaridis, P. D., Khwaja, A., Peggs, K. S., Thomson, K. J., Morris, E. C., & 1 othersPotter, V. T., Oct 2019, In: British Journal of Haematology. 187, 1, p. E20-E24

    Research output: Contribution to journalLetterpeer-review

  11. Adenoviral infections in adult T-cell depleted allogeneic stem cell transplants for myeloid disorders: Pre-emptive approach and impact on outcomes

    Mehra, V., Simini, G., Barnwell, E., Boczek, U., Widya, S., Choy, A., Raj, K., Mclornan, D., Kulasekararaj, A., de Lavallade, H., Potter, V., Marsh, J., Mufti, G. & Pagliuca, A., Jul 2019, In: Bone Marrow Transplantation. 54, p. 424-425

    Research output: Contribution to journalMeeting Abstractpeer-review

  12. Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia: a population-based study

    Kizilors, A., Crisà, E., Lea, N., Passera, R., Mian, S., Anwar, J., Best, S., Nicolini, F. E., Ireland, R., Aldouri, M., Pocock, C., Corbett, T., Gale, R., Bart-Smith, E., Weston-Smith, S., Wykes, C., Kulasekararaj, A., Jackson, S., Harrington, P., McLornan, D., & 4 othersRaj, K., Pagliuca, A., Mufti, G. J. & de Lavallade, H., May 2019, In: The Lancet Haematology. 6, 5, p. e276-e284

    Research output: Contribution to journalArticlepeer-review

  13. Targeting expanded gut homing effector T cell lineages in GI-GVHD: a new therapeutic paradigm

    Pavlidis, P., Mehra, V., Hermangild Kottoor, S., Alberts, E., Digby-Bell, J., Tsui, T-L., Scotta, C., Nova Lamperti, E. A., Emlyn, G., Abuarqoub, H., Rice, C., McLornan, D., de Lavallade, H., Potter, V., Pagliuca, A., Mufti, G. J., Raj, K., Lombardi, G., Hayee, B. H. & Powell, N., 8 Jun 2018,  Targeting expanded gut homing effector T cell lineages in GI-GVHD: a new therapeutic paradigm .

    Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

  14. EBV Reactivation Incidence and Severity in Multiple Sclerosis Patients Treated with Autologous Haematopoietic Stem Cell Transplant and Comparing with Aplastic Anaemia Treated with ATG- Single Site Experience

    Mehra, V., Pagliuca, A., de Lavallade, H., McLornan, D., Mufti, G. J., Potter, V., Raj, K., Rice, C., Rhone, E. E., Widya, S., Zuckerman, M., ware, S., Lim, C., Mccormick, J., Marsh, J., Kazmi, M., Paolo, M., malik, O. & Benson-Quarm, N., 7 Dec 2017, EBV Reactivation Incidence and Severity in Multiple Sclerosis Patients Treated with Autologous Haematopoietic Stem Cell Transplant and Comparing with Aplastic Anaemia Treated with ATG- Single Site Experience .

    Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

  15. Outcomes of Patients with Pre-Existing Invasive Fungal Disease Undergoing Allogeneic Haematopoietic Stem Cell Transplantation — 5 Years Single Centre Experience

    Mehra, V., Barnwell, E., Boczek, U., Widya, S., Raj, K., De Lavallade, H., McLornan, D., Potter, V., Rice, C., Lim, C., Kenyon, M., Bisquera, A., Marsh, J., Ceesay, M. M., Pagliuca, A. & Mufti, G., 7 Dec 2017, In: Blood. 130, Suppl 1, p. 3216 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  16. A Novel PCM1-PDGFRB Fusion in a Patient with a Chronic Myeloproliferative Neoplasm and an ins(8;5)

    Ghazzawi, M., Mehra, V., Knut, M., Brown, L., Trapper, W., Chase, A., de Lavallade, H. & Cross, N. C. P., 24 Nov 2017, In: Acta Haematologica.

    Research output: Contribution to journalArticlepeer-review

  17. Nonmyeloablative Peripheral Blood Haploidentical Stem Cell Transplantation for Refractory Severe Aplastic Anemia

    Clay, J., Kulasekararaj, A. G., Potter, V., Grimaldi, F., McLornan, D., Raj, K., de Lavallade, H., Kenyon, M., Pagliuca, T., Mufti, G. & Marsh, J. C. W., Nov 2014, In: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. 20, 11, p. 1711-1716 6 p.

    Research output: Contribution to journalArticlepeer-review

  18. Tyrosine kinase inhibitors impair B-cell immune responses in CML through off-target inhibition of kinases important for cell signaling

    de Lavallade, H., Khoder, A., Hart, M., Sarvaria, A., Sekine, T., Alsuliman, A., Mielke, S., Bazeos, A., Stringaris, K., Ali, S., Milojkovic, D., Foroni, L., Chaidos, A., Cooper, N., Gabriel, I., Apperley, J., Belsey, S., Flanagan, B., Goldman, J., Shpall, E. J., & 3 othersKelleher, P., Marin, D. & Rezvani, K., 11 Jul 2013, In: Blood. 122, 2, p. 227-238 12 p.

    Research output: Contribution to journalArticlepeer-review

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