Irene Rebollo-Mesa
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Personal profile

Research interests

I started my research career with curiosity about individual differences and the genetic aetiology of behaviour. I then developed an interest for the complex interplay between genetics and environment with an increased aim of applying research results into useful interventions. I moved to the MRC centre for transplantation with the desire of getting involved in translational research.

 At the MRC Centre I have gained extensive experience across the translational pathway, and acquired expertise in the development and validation of diagnostic and predictive tests of clinical outcomes, making use of multiple omics data. My success as embedded statistician lays in my genuine interest to understand the problem and take active part in the research process. My research interests include 1) incorporating patients preferences in the development of medical tests, taking into account the differential risk associated to low sensitivity vs. low specificity; 2) development and application of complex trial design that facilitates the transition to personalised medicine, including biomarker stratified trials and adaptive designs; and 3) application of machine learning methods that ensure robustness of the results avoiding false positive outcomes. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Postgraduate Certificate , King's College London

Award Date: 1 Jan 2013

Doctor of Science, Dimensions of Personality: A Genetic Approach, VU Amsterdam

Award Date: 1 Jan 2006

Bachelor of Science in Psychology, Universidad Autónoma de Madrid

Award Date: 1 Jan 2001

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