Search results

• 2024

  Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking

  Johnson, E. C., Austin-Zimmerman, I., Thorpe, H. H., Levey, D. F., Baranger, D. A., Colbert, S. M., Demontis, D., Khokhar, J. Y., Davis, L. K., Edenberg, H. J., Forti, M. D., Sanchez-Roige, S., Gelernter, J. & Agrawal, A., 18 Jan 2024, MedRxiv.

  Research output: Working paper/Preprint › Preprint

  • Substance Abuse 100%

• Methylomic signature of current cannabis use in two first-episode psychosis cohorts

  Dempster, E. L., Wong, C. C. Y., Burrage, J., Hannon, E., Quattrone, D., Trotta, G., Rodriguez, V., Alameda, L., Spinazzola, E., Tripoli, G., Austin-Zimmerman, I., Li, Z., Gayer-Anderson, C., Freeman, T. P., Johnson, E. C., Jongsma, H. E., Stilo, S., La Cascia, C., Ferraro, L. & La Barbera, D. & 32 others, Lasalvia, A., Tosato, S., Tarricone, I., D’Andrea, G., Galatolo, M., Tortelli, A., Pompili, M., Selten, J. P., de Haan, L., Menezes, P. R., Del Ben, C. M., Santos, J. L., Arrojo, M., Bobes, J., Sanjuán, J., Bernardo, M., Arango, C., Jones, P. B., Breen, G., Mondelli, V., Dazzan, P., Iyegbe, C., Vassos, E., Morgan, C., Mukherjee, D., van Os, J., Rutten, B., O’Donovan, M. C., Sham, P., Mill, J., Murray, R. & Di Forti, M., 2024, (Accepted/In press) In: Molecular Psychiatry.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Epigenetics 100%
  • Gene 66%
  • Epigenetic Mechanism 33%
  • Methylation 33%
  • Gene Linkage 33%

• Systematic review and meta-analysis on the effects of chronic peri-adolescent cannabinoid exposure on schizophrenia-like behaviour in rodents

  Li, Z., Mukherjee, D., Duric, B., Austin-Zimmerman, I., Trotta, G., Spinazzola, E., Quattrone, D., Murray, R. & Di Forti, M., 5 Jul 2024, (Accepted/In press) In: Molecular Psychiatry.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Behavior (Neuroscience) 100%
  • Behavioral Test 12%
  • Locomotion 12%
  • Motivation 12%
  27 Downloads (Pure)
• 2023

  Associations of antidepressants and antipsychotics with lipid parameters: Do CYP2C19/CYP2D6 genes play a role? A UK population-based study

  Richards-Belle, A., Austin-Zimmerman, I., Wang, B., Zartaloudi, E., Cotic, M., Gracie, C., Saadullah Khani, N., Wannasuphoprasit, Y., Wronska, M., Dawda, Y., Osborn, D. P. & Bramon, E., Apr 2023, In: Journal of Psychopharmacology. 37, 4, p. 396-407 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Association 100%
  • CYP2D6 100%
  • Antidepressant 100%
  • Cytochrome P450 2D6 100%
  • Cytochrome P450 2C19 100%
  6 Citations (Scopus)

• Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case–control study

  Trotta, G., Rodriguez, V., Quattrone, D., Spinazzola, E., Tripoli, G., Gayer-Anderson, C., Freeman, T. P., Jongsma, H. E., Sideli, L., Aas, M., Stilo, S. A., La cascia, C., Ferraro, L., La barbera, D., Lasalvia, A., Tosato, S., Tarricone, I., D'andrea, G., Tortelli, A. & Schürhoff, F. & 30 others, Szöke, A., Pignon, B., Selten, J.-P., Velthorst, E., De haan, L., Llorca, P.-M., Rossi menezes, P., Del ben, C. M., Santos, J. L., Arrojo, M., Bobes, J., Sanjuán, J., Bernardo, M., Arango, C., Kirkbride, J. B., Jones, P. B., Richards, A., Rutten, B. P., Van os, J., Austin-Zimmerman, I., Li, Z., Morgan, C., Sham, P. C., Vassos, E., Wong, C., Bentall, R., Fisher, H. L., Murray, R. M., Alameda, L. & Di Forti, M., Nov 2023, In: Psychological Medicine. 53, 15, p. 7375-7384 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Schizophrenia 100%
  • Psychotic Disorder 100%
  • Gene-Environment Interaction 100%
  • Psychosocial Intervention 100%
  • Emotional Abuse 100%
  2 Citations (Scopus)

• Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration

  Million Veteran Program, Austin-Zimmerman, I., Levey, D. F., Giannakopoulou, O., Deak, J. D., Galimberti, M., Adhikari, K., Zhou, H., Denaxas, S., Irizar, H., Kuchenbaecker, K., McQuillin, A., Concato, J., Buysse, D. J., Gaziano, J. M., Gottlieb, D. J., Polimanti, R., Stein, M. B., Bramon, E. & Gelernter, J., 28 Sept 2023, In: Nature Communications. 14, 1, p. 6059

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genetic Correlation 100%
  • Heritability 50%
  • Single Nucleotide Polymorphism 50%
  • Mendelian Randomization 50%
  • Linkage Disequilibrium 50%
  5 Citations (Scopus)

• Psychosis Endophenotypes: A Gene-Set-Specific Polygenic Risk Score Analysis

  Genetic Risk and Outcome of Psychosis (GROUP) Study, Psychosis Endophenotypes International Consortium (PEIC) & Wang, B., Nov 2023, In: Schizophrenia Bulletin. 49, 6, p. 1625-1636 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Forebrain 100%
  • Brain 49%
  • Brain Development 49%
  • Bipolar Disorder 49%
  1 Citation (Scopus)

• The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study

  EU-GEI WP2 Group, Spinazzola, E., Quattrone, D., Rodriguez, V., Trotta, G., Alameda, L., Tripoli, G., Gayer-Anderson, C., Freeman, T. P., Johnson, E. C., Jongsma, H. E., Stilo, S., La Cascia, C., Ferraro, L., La Barbera, D., Lasalvia, A., Tosato, S., Tarricone, I., D'Andrea, G. & Galatolo, M. & 26 others, Tortelli, A., Tagliabue, I., Turco, M., Pompili, M., Selten, J.-P., de Haan, L., Rossi Menezes, P., Del Ben, C. M., Santos, J. L., Arrojo, M., Bobes, J., Sanjuán, J., Bernardo, M., Arango, C., Kirkbride, J. B., Jones, P. B., O'Donovan, M., Rutten, B. P., Van Os, J., Morgan, C., Sham, P. C., Austin-Zimmerman, I., Li, Z., Vassos, E., Murray, R. M. & Di Forti, M., Nov 2023, In: Psychological medicine. 53, 15, p. 7418-7427 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Psychotic Disorder 100%
  • Gene-Environment Interaction 100%
  1 Citation (Scopus)
• 2022

  Adolescent Verbal Memory as a Psychosis Endophenotype: A Genome-Wide Association Study in an Ancestrally Diverse Sample

  Wang, B., Giannakopoulou, O., Austin-zimmerman, I., Irizar, H., Harju-seppänen, J., Zartaloudi, E., Bhat, A., Mcquillin, A., Kuchenbäcker, K. & Bramon, E., 3 Jan 2022, In: Genes. 13, 1, p. 106 106.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genome Wide Association Study 100%
  • Psychosis 100%
  • Endophenotype 100%
  • Schizophrenia 33%
  • Inclusion 33%
  2 Citations (Scopus)

• CYP2D6 Genetic Variation and Antipsychotic-Induced Weight Gain: A Systematic Review and Meta-Analysis

  Wannasuphoprasit, Y., Andersen, S. E., Arranz, M. J., Catalan, R., Jurgens, G., Kloosterboer, S. M., Rasmussen, H. B., Bhat, A., Irizar, H., Koller, D., Polimanti, R., Wang, B., Zartaloudi, E., Austin-zimmerman, I. & Bramon, E., 3 Feb 2022, In: Frontiers in Psychology. 12, 768748.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antipsychotic 100%
  • Cytochrome P450 2D6 100%
  • Body Mass Index 85%
  • Cohort Study 28%
  • Liver 12%
  11 Citations (Scopus)
• 2021

  Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study

  Thygesen, J. H., Presman, A., Harju-seppänen, J., Irizar, H., Jones, R., Kuchenbaecker, K., Lin, K., Alizadeh, B. Z., Austin-zimmerman, I., Bartels-velthuis, A., Bhat, A., Bruggeman, R., Cahn, W., Calafato, S., Crespo-facorro, B., De Haan, L., De Zwarte, S. M. C., Di Forti, M., Díez-revuelta, Á. & Hall, J. & 37 others, Hall, M.-H., Iyegbe, C., Jablensky, A., Kahn, R., Kalaydjieva, L., Kravariti, E., Lawrie, S., Luykx, J. J., Mata, I., Mcdonald, C., Mcintosh, A. M., Mcquillin, A., Muir, R., Ophoff, R., Picchioni, M., Prata, D. P., Ranlund, S., Rujescu, D., Rutten, B. P. F., Schulze, K., Shaikh, M., Schirmbeck, F., Simons, C. J. P., Toulopoulou, T., Van Amelsvoort, T., Van Haren, N., Van Os, J., Van Winkel, R., Vassos, E., Walshe, M., Weisbrod, M., Zartaloudi, E., Bell, V., Powell, J., Lewis, C. M., Murray, R. M. & Bramon, E., 1 Sept 2021, In: Molecular Psychiatry. 26, 9, p. 5307-5319

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cognition 100%
  • Cognitive Function 16%
  • Reasoning 16%
  • Block Design 16%
  21 Citations (Scopus)

• The Influence of CYP2D6 and CYP2C19 Genetic Variation on Diabetes Mellitus Risk in People Taking Antidepressants and Antipsychotics

  Austin-zimmerman, I., Wronska, M., Wang, B., Irizar, H., Thygesen, J. H., Bhat, A., Denaxas, S., Fatemifar, G., Finan, C., Harju-seppänen, J., Giannakopoulou, O., Kuchenbaecker, K., Zartaloudi, E., Mcquillin, A. & Bramon, E., 3 Nov 2021, In: Genes. 12, 11, p. 1758

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Transcriptome-wide association study reveals two genes that influence mismatch negativity

  Bhat, A., Irizar, H., Thygesen, J. H., Kuchenbaecker, K., Pain, O., Adams, R. A., Zartaloudi, E., Harju-seppänen, J., Austin-zimmerman, I., Wang, B., Muir, R., Summerfelt, A., Du, X. M., Bruce, H., O’donnell, P., Srivastava, D. P., Friston, K., Hong, L. E., Hall, M.-H. & Bramon, E., 16 Mar 2021, In: Cell Reports. 34, 11, 108868.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transcriptome 100%
  • Frontal Lobe 10%
  • Sensory Processing 10%
  10 Citations (Scopus)
• 2020

  The effect of CYP2D6 variation on antipsychotic-induced hyperprolactinaemia: a systematic review and meta-analysis

  Calafato, M. S., Austin-zimmerman, I., Thygesen, J. H., Sairam, M., Metastasio, A., Marston, L., Abad-santos, F., Bhat, A., Harju-seppänen, J., Irizar, H., Zartaloudi, E. & Bramon, E., 1 Oct 2020, In: PHARMACOGENOMICS JOURNAL. 20, 5, p. 629-637

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)