Ivor Mason
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Research interests

Cell-cell signalling processes that direct embryonic brain development. We use a variety of approaches and experimental systems both in vivo and in vitro to understand how local signalling processes direct various crucial aspects of brain development. These include closure of the neural tube, giving regional identity to parts of the brain, controling growth and differentiation of neurons and directing cell movements and axon pathfinding.

We study these processes in a range of vertebrate model organisms: transgenic mice, chick embryos and zebrafish embryos, while also using explant or cell culture approaches where applicable.

Currently our work focuses on signalling by FGFs, BMPs and through the planar cell polarity pathway. Our work on FGFs is set in context in the following review, which will give a flavour of our research interests:

Mason. I. (2007) Initiation to end-point: multiple roles of fibroblast growth factors in neural development. Nature Reviews Neuroscience 8, 583-596. PMID: 17637802

Research interests (short)

Cell-cell signalling processes that direct embryonic brain development.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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