Research output per year
Research output per year
Personal profile
Research interests
My work is focused on the development and application of diffusion MRI methods, particularly those that relate to the characterisation of white matter and its connectivity. I have worked particularly on:
- the design of acquisition schemes for high angular resolution diffusion imaging (HARDI);
- estimating fibre orientations in a crossing fibre context via spherical deconvolution;
- probabilistic tractography methods and related applications such as Track Density Imaging (TDI), Anatomically Constrained Tractography (ACT), andspherical deconvolution informed filtering of tracks (SIFT);
- Apparent Fibre Density (AFD) methods for group-wise fixel-based analysis of whole brain diffusion MRI data (fixel: fibre element - a fibre population within an imaging voxel);
- advocating the use of higher-order models for clinical applications, particularly neurosurgery.
I am currently interested in identifying the best imaging parameters for neonatal diffusion MRI, specifically for use in the Developing Human Connectome Project (dHCP). I am also investigating methods for the analysis of multi-shell HARDI data.
Software
Much of my research output is available for use in the open-source software package MRtrix, with the latest development efforts going into the next major release, MRtrix3 (already available, but currently still in beta).
Biographical details
I complete my PhD in 2003 under the supervision of Alan Connelly and Fernando Calamante in the UCL Institute of Child Health, In 2005, I joined the Brain Research Institute in Melbourne, Australia, which was later amalgamated into the Florey Institutes of Neuroscience and Mental Health. In 2013, I joined the Department of Biomedical Engineering at King's College London, working within the Department of Perinatal Imaging and Health, located within St Thomas's Hospital, London.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Diffusion tensor magnetic resonance imaging and fibre tractography in the brain, UCL University College London
Award Date: 1 Jan 2003
Master of Science, Evaluation of trabecular bone architecture using MRI data, University of Cambridge
Award Date: 1 Jan 1999
Bachelor of Arts, University of Cambridge
Award Date: 1 Jan 1998
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Collaborations and top research areas from the last five years
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Autism common variants associated with white matter alterations at birth: cross-sectional fixel-based analyses of 221 European term-born neonates from the developing human connectome project
Le, H., Bonthrone, A., Uus, A., Fenchel, D., Lautarescu, A., Dimitrakopoulou, K., Edwards, D., Hajnal, J., Counsell, S., Cordero-Grande, L., Christiaens, D., Batalle, D., Pietsch, M., Price, A., Patel, H., Curtis, C., Cullen, H., Deprez, M. & Tournier, J.-D., 21 Jan 2025, (Accepted/In press) In: Translational psychiatry.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Downloads (Pure) -
Autism spectrum disorder common variants associated with regional lobe volume variations at birth: cross-sectional study in 273 European term neonates in developing Human Connectome Project
Le, H., Fenchel, D., Dimitrakopoulou, K., Patel, H., Curtis, C., Cordero-Grande, L., Edwards, D., Hajnal, J., Tournier, J.-D., Deprez, M. & Cullen, H., 21 Jan 2025, (Accepted/In press) In: Translational psychiatry.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Downloads (Pure) -
Individualized cortical gyrification in neonates with congenital heart disease
Cromb, D., Wilson, S., Bonthrone, A., Chew, A., Kelly, C., Kumar, M., Cawley, P., Dimitrova, R., Tournier, J.-D., Pushparajah, K., Simpson, J., Rutherford, M., Hajnal, J., Edwards, D., Nosarti, C., O'Muircheartaigh, J. & Counsell, S., 7 Oct 2024, In: Brain Communications. 6, 5, fcae356.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
A Deep Learning Approach for Segmenting the Subplate and Proliferative Zones in Fetal Brain MRI
Sousa, H. S., Fukami-Gartner, A., Uus, A. U., Kyriakopoulou, V., Ziukaite, B., Anzak, I., O’Muircheartaigh, J., Hajnal, J. V., Tournier, J. D., Hammers, A., Rutherford, M. A. & Deprez, M., 12 Oct 2023, Perinatal, Preterm and Paediatric Image Analysis - 8th International Workshop, PIPPI 2023, Held in Conjunction with MICCAI 2023, Proceedings. Link-Sourani, D., Abaci Turk, E., Macgowan, C., Hutter, J., Hutter, J., Melbourne, A., Licandro, R. & Licandro, R. (eds.). Springer Science and Business Media Deutschland GmbH, p. 17-27 11 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 14246 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Conference paper › peer-review
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Diffusion MRI of the facial-vestibulocochlear nerve complex: a prospective clinical validation study
Shapey, J., Vos, S. B., Mancini, L., Sanders, B., Thornton, J. S., Tournier, J. D., Saeed, S. R., Kitchen, N., Khalil, S., Grover, P., Bradford, R., Dorent, R., Sparks, R., Vercauteren, T., Yousry, T., Bisdas, S. & Ourselin, S., Nov 2023, In: European Radiology. 33, 11, p. 8067-8076 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus)
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MRtrix: enabling advanced tractography and microstructure analysis of diffusion MRI in the brain
Tournier, J.-D. (Primary Investigator)
EPSRC Engineering and Physical Sciences Research Council
1/10/2022 → 30/09/2025
Project: Research
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Neurodevelopment from the fetus to childhood in individuals with congenital heart disease
Counsell, S. (Primary Investigator), Edwards, D. (Co-Investigator), Hajnal, J. (Co-Investigator), Nosarti, C. (Co-Investigator), Pushparajah, K. (Co-Investigator), Rutherford, M. (Co-Investigator) & Tournier, J.-D. (Co-Investigator)
1/03/2021 → 28/02/2026
Project: Research
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Wellcome/EPSRC Centre for Medical Engineering Extension
Ourselin, S. (Primary Investigator), Barker, G. (Co-Investigator), Barnes, A. (Co-Investigator), Barrington, S. (Co-Investigator), Bergeles, C. (Co-Investigator), Bishop, M. (Co-Investigator), Blower, P. (Co-Investigator), Booth, T. (Co-Investigator), Botnar, R. (Co-Investigator), Cardoso, J. (Co-Investigator), Carmichael, D. (Co-Investigator), Chiribiri, A. (Co-Investigator), Clough, R. (Co-Investigator), Cook, G. (Co-Investigator), Counsell, S. (Co-Investigator), Dasgupta, P. (Co-Investigator), De Vecchi, A. (Co-Investigator), De Vita, E. (Co-Investigator), Edwards, D. (Co-Investigator), Goh, V. (Co-Investigator), Hajnal, J. (Co-Investigator), Hammers, A. (Co-Investigator), Hutter, J. (Co-Investigator), Ipek, O. (Co-Investigator), King, A. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Liu, H. (Co-Investigator), Malik, S. (Co-Investigator), Marsden, P. (Co-Investigator), Modat, M. (Co-Investigator), Niederer, S. (Co-Investigator), Razavi, R. (Co-Investigator), Reader, A. (Co-Investigator), Rhode, K. (Co-Investigator), Roujol, S. (Co-Investigator), Rutherford, M. (Co-Investigator), Shapey, J. (Co-Investigator), Sparks, R. (Co-Investigator), T. M. de Rosales, R. (Co-Investigator), Terry, S. (Co-Investigator), Tournier, J.-D. (Co-Investigator), Vercauteren, T. (Co-Investigator), Williams, S. (Co-Investigator), Xia, W. (Co-Investigator), Young, A. (Co-Investigator) & academic, A. (Co-Investigator)
28/04/2022 → 27/10/2024
Project: Research
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Ultra-high resolution 7T MRI mapping of basal ganglia connectivity on an individual patient basis for Paediatric Deep Brain Stimulation (DBS)
Lumsden, D. (Primary Investigator), Edwards, D. (Co-Investigator), Hajnal, J. (Co-Investigator), Arichi, T. (Co-Investigator), McClelland, V. (Co-Investigator) & Tournier, J.-D. (Co-Investigator)
1/10/2020 → 30/09/2023
Project: Research
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Brain development and neurodevelopmental performance in children with congenital heart disease
Counsell, S. (Primary Investigator), Batalle, D. (Co-Investigator), Nosarti, C. (Co-Investigator), Tournier, J.-D. (Co-Investigator), Victor, S. (Co-Investigator) & Rutherford, M. (Co-Investigator)
1/04/2018 → 30/09/2020
Project: Research
Activities
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Discovery Outstanding Researcher Award
Tournier, J.-D. (Recipient)
1 Jan 2013 → 1 Sept 2013Activity: Other › Types of Award - Fellowship awarded competitively
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Frontiers in Neurology (Journal)
Tournier, J.-D. (Peer reviewer)
2013Activity: Publication peer-review and editorial work › Publication peer-review
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Diffusion MR Study Group, Program Director
Tournier, J.-D. (Recipient)
May 2011 → May 2013Activity: Other › Types of Award - Election to learned society
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PloS one (Journal)
Tournier, J.-D. (Peer reviewer)
2011Activity: Publication peer-review and editorial work › Publication peer-review
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Frontiers in Neuroscience (Journal)
Tournier, J.-D. (Peer reviewer)
2011Activity: Publication peer-review and editorial work › Publication peer-review
Prizes
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2014 Editor's Choice Award
Tournier, J.-D. (Recipient), Jun 2014
Prize: Prize (including medals and awards)
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Outstanding Teacher Award
Tournier, J.-D. (Recipient), May 2006
Prize: Prize (including medals and awards)
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