King's College London

Research portal

Dr James MacCabe

Research interests

After an intercalated BSc in Psychology and Basic Medical Sciences, Dr MacCabe qualified in medicine at the University of London in 1995 and completed his basic and higher specialist training in Psychiatry at the Maudsley Hospital from 1997 to 2004. He obtained a joint MRC/Department of Health Special Training Fellowship in Health of the population research in 2004, in collaboration with the Department of Medical Epidemiology and Biostatistics at Karolinska Institute, Stockholm. He obtained an MSc in Epidemiology from the London School of Hygiene and Tropical Medicine in 2006 and a PhD in 2008. In 2009 he was awarded a Clinical Senior Lectureship by the Higher Education Funding Council for England.

Dr MacCabe has been honorary consultant psychiatrist at the National Psychosis Unit since 2005, where he is responsible for treating inpatients with severe psychosis and conducting clinical trials. Dr MacCabe serves on the Board of Trustees of the mental health charity, SANE.

Dr MacCabe's research in treatment refractory schizophrenia personalised medicine mirrors his clinical work, and is geared towards helping people whose psychosis has not responded to standard antipsychotic treatment.  His research includes work on the epidemiology, genetics and neurochemistry underlying treatment refractory schizophrenia, and identifying biomarkers that may be used in personalised medicine. Much of his research is conducted in collaboration with UK and international partners. 

Editorial activity

Maudsley Publications Committee (Journal)

James MacCabe (Editor)
20102020

Activity: Publication peer-review and editorial workEditorial activity

European Psychiatry (Journal)

James MacCabe (Editorial board member)
2005 → …

Activity: Publication peer-review and editorial workEditorial activity

ial Board, European Psychiatry (Journal)

James MacCabe (Editor)
20052015

Activity: Publication peer-review and editorial workEditorial activity

Participation in conference

“Premorbid cognitive decline in schizophrenia: a longitudinal population based study”. Psychosis Studies Meeting, Institute of Psychiatry

James MacCabe (Invited speaker)
Feb 2011 → …

Activity: Participating in or organising an eventParticipation in conference

“Premorbid cognitive decline in schizophrenia: a longitudinal population based study”. Winter Workshop in Psychoses, Innsbruck, Austria

James MacCabe (Speaker)
Feb 2011 → …

Activity: Participating in or organising an eventParticipation in conference

“Trajectories of IQ during adolescence and risk for psychosis in adulthood.” University of Gothenberg, Sweden, ‘UGU’ meeting

James MacCabe (Invited speaker)
Oct 2010 → …

Activity: Participating in or organising an eventParticipation in conference

“Adverse effects of clozapine and how to treat them.” Symposium on treatment resistant psychosis, Royal College of Psychiatrists’ Annual Conference

James MacCabe (Keynote/plenary speaker)
Jun 2010 → …

Activity: Participating in or organising an eventParticipation in conference

“School performance and risk for psychosis: is mania brainier?” Seminar, Centre for Psychiatry, Barts and the London School of Medicine and Dentistry

James MacCabe (Invited speaker)
2010 → …

Activity: Participating in or organising an eventParticipation in conference

“Improving the tolerability of Clozapine” , Royal College of Psychiatrists, Faculty of Rehabilitation Annual conference

James MacCabe (Keynote/plenary speaker)
2010 → …

Activity: Participating in or organising an eventParticipation in conference

“The schizophrenia Paradox: Fertility in schizophrenic patients and their relatives”. Winter Workshop in Psychoses, Barcelona, Spain

James MacCabe (Invited speaker)
Nov 2009 → …

Activity: Participating in or organising an eventParticipation in conference

“Bipolars are Brilliant”. Schizophrenia – The Final Frontier: Feschrift for Prof Robin Murray

James MacCabe (Keynote/plenary speaker)
Nov 2009 → …

Activity: Participating in or organising an eventParticipation in conference

“Adverse pregnancy outcomes in mothers with affective psychosis”. Nordic Psychiatric Congress, Stockholm, Sweden

James MacCabe (Keynote/plenary speaker)
Oct 2009 → …

Activity: Participating in or organising an eventParticipation in conference

Nordic Psychiatric Congress, Stockholm, Sweden (Co-chaired session)

James MacCabe (Chair)
Oct 2009 → …

Activity: Participating in or organising an eventParticipation in conference

“Reproductive success in schizophrenia and bipolar disorder” Winter Workshop on schizophrenia research, Montreaux, Switzerland

James MacCabe (Speaker)
Nov 2008 → …

Activity: Participating in or organising an eventParticipation in conference

“There would be no genius without madness – 37th Maudsley Debate” (Chair)

James MacCabe (Chair)
Jul 2008 → …

Activity: Participating in or organising an eventParticipation in conference

“School performance in schizophrenia and bipolar disorder: is mania brainier?” Psychosis Interest Group, IoP

James MacCabe (Invited speaker)
Jun 2008 → …

Activity: Participating in or organising an eventParticipation in conference

“Lifecourse research on psychosis”. Centre for Health, Equity and Social Studies, University of Stockholm, Sweden

James MacCabe (Invited speaker)
May 2008 → …

Activity: Participating in or organising an eventParticipation in conference

“Pregnancy outcomes of mothers with bipolar disorders.” ISAD 4th biennial conference, Cape Town, South Africa

James MacCabe (Keynote/plenary speaker)
May 2008 → …

Activity: Participating in or organising an eventParticipation in conference

“What can psychiatric epidemiologists can learn from life-course epidemiology?” Seminar on Lifecourse Epidemiology, IoP

James MacCabe (Invited speaker)
Apr 2008 → …

Activity: Participating in or organising an eventParticipation in conference

Epidemiology Interest Group Symposium: The use, abuse and pitfalls of longitudinal data: What can we learn from a life course epidemiological approach? (Chair and organiser)

James MacCabe (Organiser)
Apr 2008 → …

Activity: Participating in or organising an eventParticipation in conference

Half-Day Seminar on Lifecourse Epidemiology, Institute of Psychiatry

James MacCabe (Chair)
Apr 2008 → …

Activity: Participating in or organising an eventParticipation in conference

“The Aetiology of Schizophrenia”. Ravenswood Medium Secure Unit, Portsmouth, UK

James MacCabe (Invited speaker)
Mar 2008 → …

Activity: Participating in or organising an eventParticipation in conference

“Fertility and Schizophrenia: a paradox no longer”. European Maudsley Forum, Palermo, Italy

James MacCabe (Keynote/plenary speaker)
2008 → …

Activity: Participating in or organising an eventParticipation in conference

European Maudsley Forum, Palermo, Italy. (also chaired two sessions)

James MacCabe (Chair)
2008 → …

Activity: Participating in or organising an eventParticipation in conference

“Scholastic antecedents of schizophrenia and bipolar disorder in a large Swedish cohort.” Congress of the Icelandic Psychiatric Association, Reykjavik, Iceland

James MacCabe (Speaker)
May 2007 → …

Activity: Participating in or organising an eventParticipation in conference

“School performance at age 16 has contrasting effects on risk of later bipolar disorder and schizophrenia

James MacCabe (Invited speaker)
Nov 2006 → …

Activity: Participating in or organising an eventParticipation in conference

“General psychiatry and Epidemiology research at the IoP”: Psychosis IRG “At Home” meeting, IoP

James MacCabe (Invited speaker)
Oct 2006 → …

Activity: Participating in or organising an eventParticipation in conference

Chaired session on psychosis, International Mental Health conference, IoP

James MacCabe (Chair)
Jul 2006 → …

Activity: Participating in or organising an eventParticipation in conference

“School performance at age 16 has contrasting effects on risk of later bipolar disorder and schizophrenia

James MacCabe (Keynote/plenary speaker)
Jun 2006 → …

Activity: Participating in or organising an eventParticipation in conference

Gender differences in age at onset in schizophrenia; a meta-analysis, International Congress on Schizophrenia Research, Savannah, GA, USA

James MacCabe (Speaker)
Mar 2005 → …

Activity: Participating in or organising an eventParticipation in conference

“Pregnancy Outcomes in Mothers with Affective Psychosis: a Swedish Population Register Study”, Epidemiology Seminar Series, IoP

James MacCabe (Invited speaker)
Sep 2004 → …

Activity: Participating in or organising an eventParticipation in conference

“Superphrenia: Is it possible to have schizophrenia with normal cognitive function?”, Cognition in Schizophrenia conference, IoP

James MacCabe (Speaker)
Apr 2004 → …

Activity: Participating in or organising an eventParticipation in conference

International Conference: Gene-Environment Interactions in Psychiatry

James MacCabe (Organiser)
2004 → …

Activity: Participating in or organising an eventParticipation in conference

“Pregnancy Outcomes in Bipolar Mothers”, Psychosis Interest Group, IoP

James MacCabe (Invited speaker)
Jun 2003 → …

Activity: Participating in or organising an eventParticipation in conference

“Cognitive decline is associated with reduced white matter in schizophrenia”, 27th Nordic Psychiatric Congress, Reykjavik, Iceland

James MacCabe (Speaker)
May 2003 → …

Activity: Participating in or organising an eventParticipation in conference

“Modest Excess of Obstetric complication in the offspring of bipolar mothers”, 27th Nordic Psychiatric Congress, Reykjavik, Iceland

James MacCabe (Speaker)
May 2003 → …

Activity: Participating in or organising an eventParticipation in conference

“Cognitive decline is associated with loss of white matter in schizophrenia”, Mt. Sinai Conference on Cognition in Schizophrenia, Davos, Switzerland

James MacCabe (Speaker)
Mar 2002 → …

Activity: Participating in or organising an eventParticipation in conference

“Aetiology and Outcome in Graduates with Schizophrenia”, Royal Coll. Psychiatrists Annual General Meeting, Birmingham

James MacCabe (Speaker)
Jun 1999 → …

Activity: Participating in or organising an eventParticipation in conference

“Aetiology and Symptomatology in Graduates with Schizophrenia”, Psychosis Interest Group, Institute of Psychiatry

James MacCabe (Invited speaker)
Apr 1999 → …

Activity: Participating in or organising an eventParticipation in conference

“Unitary Psychosis”. Journal Club, IoP

James MacCabe (Invited speaker)
Jun 1997 → …

Activity: Participating in or organising an eventParticipation in conference

Types of Public engagement and outreach - Public lecture/debate/seminar

Director of Maudsley Debates

James MacCabe (Host)
2008 → …

Activity: OtherTypes of Public engagement and outreach - Public lecture/debate/seminar

Publication peer-review

Referee to numerous international journals (Journal)

James MacCabe (Editor)
20002035

Activity: Publication peer-review and editorial workPublication peer-review

Types of Business and Community - Work on advisory panel to industry or government or non-government organisation

SANE

James MacCabe (Advisor)
2009 → …

Activity: OtherTypes of Business and Community - Work on advisory panel to industry or government or non-government organisation

Types of External academic engagement - Membership of external research organisation

the Royal College of Psychiatrists

James MacCabe (Member)
20002035

Activity: OtherTypes of External academic engagement - Membership of external research organisation

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