King's College London

Research portal

Dr James MacCabe

  1. Negative symptoms in early-onset psychosis and their association with antipsychotic treatment failure

    Downs, J., Dean, H., Lechler, S., Sears, N., Patel, R., Shetty, H., Hotopf, M., Ford, T., Kyriakopoulos, M., Diaz-Caneja, C. M., Arango, C., MacCabe, J. H., Hayes, R. D. & Pina-Camacho, L. 1 Jan 2019 In : Schizophrenia Bulletin. 45, 1, p. 69-79 11 p.

    Research output: Contribution to journalArticle

  2. Accepted/In press

    Hyoscine for clozapine-induced hypersalivation: a double-blind, randomised, placebo-controlled crossover trial

    Segev, A., Evans, A., Hodsoll, J., Whiskey, E., Syed Sheriff, R., Shergill, S. S. & MacCabe, J. H. 10 Dec 2018 (Accepted/In press) In : International Clinical Psychopharmacology.

    Research output: Contribution to journalArticle

  3. Accepted/In press
  4. Neuropsychological function at first episode in treatment-resistant psychosis: Findings from the ÆsOP-10 study

    Kravariti, E., Demjaha, A., Zanelli, J., Ibrahim, F., Wise, C., Maccabe, J. H., Reichenberg, A., Pilecka, I., Morgan, K., Fearon, P., Morgan, C., Doody, G. A., Donoghue, K., Jones, P. B., Kaçar, A. Ş., Dazzan, P., Lappin, J. & Murray, R. M. 23 Oct 2018 In : Psychological Medicine.

    Research output: Contribution to journalArticle

  5. Constipation, ileus and medication use during clozapine treatment in patients with schizophrenia in Iceland

    Ingimarsson, O., MacCabe, J. H. & Sigurdsson, E. 22 Oct 2018 In : Nordic Journal of Psychiatry. p. 1-4 4 p.

    Research output: Contribution to journalArticle

  6. Biological predictors of clozapine response: A systematic review

    Samanaite, R., Gillespie, A., Sendt, K. V., McQueen, G., MacCabe, J. H. & Egerton, A. 26 Jul 2018 In : Frontiers in Psychiatry. 9, JUL, 327

    Research output: Contribution to journalReview article

  7. Artistic creativity and risk for schizophrenia, bipolar disorder and unipolar depression: a Swedish population-based case-control study and sib-pair analysis

    MacCabe, J. H., Sariaslan, A., Almqvist, C., Lichtenstein, P., Larsson, H. & Kyaga, S. Jun 2018 In : The British journal of psychiatry : the journal of mental science. 212, 6, p. 370-376

    Research output: Contribution to journalArticle

  8. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

    Pardiñas, A. F. , Holmans, P. , Pocklington, A. J. , Escott-Price, V. , Ripke, S. , Carrera, N. , Legge, S. E. , Bishop, S. , Cameron, D. , Hamshere, M. L. , Han, J. , Hubbard, L. , Lynham, A. , Mantripragada, K. , Rees, E. , MacCabe, J. H. , McCarroll, S. A. , Baune, B. T. , Breen, G. , Byrne, E. M. & 31 others Dannlowski, U., Eley, T. C., Hayward, C., Martin, N. G., McIntosh, A. M., Plomin, R., Porteous, D. J., Wray, N. R., Caballero, A., Geschwind, D. H., Huckins, L. M., Ruderfer, D. M., Santiago, E., Sklar, P., Stahl, E. A., Won, H., Agerbo, E., Als, T. D., Andreassen, O. A., Bækvad-Hansen, M., Mortensen, P. B., Pedersen, C. B., Børglum, A. D., Bybjerg-Grauholm, J., Djurovic, S., Durmishi, N., Pedersen, M. G., Golimbet, V., Grove, J., Collier, D. A. & GERAD1 Consortium: 26 Feb 2018 In : Nature Genetics.

    Research output: Contribution to journalArticle

  9. Validation of an algorithm-based definition of treatment resistance in patients with schizophrenia

    Ajnakina, O., Horsdal, H. T., Lally, J., MacCabe, J. H., Murray, R. M., Gasse, C. & Wimberley, T. 19 Feb 2018 In : Schizophrenia Research.

    Research output: Contribution to journalArticle

  10. Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

    Legge, S. E. , Hamshere, M. L. , Ripke, S. , Pardinas, A. F. , Goldstein, J. I. , Rees, E. , Richards, A. L. , Leonenko, G. , Jorskog, L. F. , Chambert, K. D. , Collier, D. A. , Genovese, G. , Giegling, I. , Holmans, P. , Jonasdottir, A. , Kirov, G. , McCarroll, S. A. , MacCabe, J. H. , Mantripragada, K. , Moran, J. L. & 9 others Neale, B. M., Stefansson, H., Rujescu, D., Daly, M. J., Sullivan, P. F., Owen, M. J., O'Donovan, M. C., Walters, J. T. R. & Clozapine-Induced Agranulocytosis Consortium Jan 2018 In : Molecular Psychiatry. 23, 1, p. 162-163 2 p.

    Research output: Contribution to journalArticle

  11. Mortality and Self-Harm in Association With Clozapine in Treatment-Resistant Schizophrenia

    Wimberley, T., MacCabe, J. H., Laursen, T. M., Sørensen, H. J., Astrup, A., Horsdal, H. T., Gasse, C. & Støvring, H. 1 Oct 2017 In : The American Journal of Psychiatry. 174, 10, p. 990-998 9 p.

    Research output: Contribution to journalArticle

  12. The Use of Granulocyte Colony-Stimulating Factor in Clozapine Rechallenge: A Systematic Review

    Lally, J., Malik, S., Krivoy, A., Whiskey, E., Taylor, D. M., Gaughran, F. P., Flanagan, R. J., Mijovic, A. & Maccabe, J. H. 1 Oct 2017 In : Journal of Clinical Psychopharmacology. 37, 5, p. 600-604 5 p.

    Research output: Contribution to journalReview article

  13. Polygenic Risk Score for Schizophrenia and Treatment-Resistant Schizophrenia

    Wimberley, T., Gasse, C., Meier, S. M., Agerbo, E., MacCabe, J. H. & Horsdal, H. T. Sep 2017 In : Schizophrenia Bulletin. 43, 5, p. 1064–1069

    Research output: Contribution to journalArticle

  14. Risk of diabetes and dyslipidemia during clozapine and other antipsychotic drug treatment of schizophrenia in Iceland

    Ingimarsson, O., MacCabe, J. H., Haraldsson, M., Jónsdóttir, H. & Sigurdsson, E. 20 Jun 2017 In : Nordic Journal of Psychiatry. p. 1-7 7 p.

    Research output: Contribution to journalArticle

  15. Educational level, underachievement and general mental health problems in 10 866 adolescents

    Tempelaar, W. M., de Vos, N., Plevier, C. M., van Gastel, W. A., Termorshuizen, F., MacCabe, J. H. & Boks, M. P. M. 26 Apr 2017 In : Academic Pediatrics.

    Research output: Contribution to journalArticle

  16. Predictors of nonhospitalization and functional response in clozapine treatment: A nationwide, population-based cohort study

    Köhler-Forsberg, O., Horsdal, H. T., Legge, S. E., MacCabe, J. & Gasse, C. 1 Apr 2017 In : Journal of Clinical Psychopharmacology. 37, 2, p. 148-154 7 p.

    Research output: Contribution to journalArticle

  17. Effects of a smoking ban on clozapine plasma concentrations in a nonsecure psychiatric unit

    Gee, S. H., Taylor, D. M., Shergill, S. S., Flanagan, R. & MacCabe, J. H. 1 Feb 2017 In : Therapeutic Advances in Psychopharmacology. 7, 2, p. 79-83 5 p.

    Research output: Contribution to journalArticle

  18. Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology

    Howes, O. D. , McCutcheon, R. , Agid, O. , de Bartolomeis, A. , van Beveren, N. J. M. , Birnbaum, M. L. , Bloomfield, M. A. P. , Bressan, R. A. , Buchanan, R. W. , Carpenter, W. T. , Castle, D. J. , Citrome, L. , Daskalakis, Z. J. , Davidson, M. , Drake, R. J. , Dursun, S. , Ebdrup, B. H. , Elkis, H. , Falkai, P. , Fleischacker, W. W. & 31 others Gadelha, A., Gaughran, F., Glenthøj, B. Y., Graff-Guerrero, A., Hallak, J. E. C., Honer, W. G., Kennedy, J., Kinon, B. J., Lawrie, S. M., Lee, J., Leweke, F. M., MacCabe, J. H., McNabb, C. B., Meltzer, H., Möller, H-J., Nakajima, S., Pantelis, C., Reis Marques, T., Remington, G., Rossell, S. L., Russell, B. R., Siu, C. O., Suzuki, T., Sommer, I. E., Taylor, D., Thomas, N., Üçok, A., Umbricht, D., Walters, J. T. R., Kane, J. & Correll, C. U. 6 Dec 2016 In : The American Journal of Psychiatry. appiajp201616050503

    Research output: Contribution to journalArticle

  19. Educational achievement in psychiatric patients and their siblings: a register-based study in 30 000 individuals in The Netherlands

    Tempelaar, W. M., Termorshuizen, F., MacCabe, J. H., Boks, M. P. M. & Kahn, R. S. 22 Nov 2016 In : Psychological Medicine. 9 p.

    Research output: Contribution to journalArticle

  20. Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

    Legge, S. E. , Hamshere, M. L. , Ripke, S. , Pardinas, A. F. , Goldstein, J. I. , Rees, E. , Richards, A. L. , Leonenko, G. , Jorskog, L. F. , Chambert, K. D. , Collier, D. A. , Genovese, G. , Giegling, I. , Holmans, P. , Jonasdottir, A. , Kirov, G. , McCarroll, S. A. , MacCabe, J. H. , Mantripragada, K. , Moran, J. L. & 9 others Neale, B. M., Stefansson, H., Rujescu, D., Daly, M. J., Sullivan, P. F., Owen, M. J., O'Donovan, M. C., Walters, J. T. R. & Clozapine-Induced Agranulocytosis Consortium 12 Jul 2016 In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  21. Sudden-Onset Catatonia Following Clozapine Withdrawal: A Case Report

    Koychev, I., Hadjiphilippou, S., Lynch, J., Whelan, P. & MacCabe, J. Jul 2016 In : Journal of Clinical Psychiatry. 77, 7, p. e899

    Research output: Contribution to journalLetter

  22. Inverse association between urbanicity and treatment resistance in schizophrenia

    Wimberley, T., Pedersen, C. B., MacCabe, J. H., Støvring, H., Astrup, A., Sørensen, H. J., Horsdal, H. T., Mortensen, P. B. & Gasse, C. 8 Apr 2016 In : Schizophrenia Research.

    Research output: Contribution to journalArticle

  23. Clozapine treatment and discontinuation in Iceland: A national longitudinal study using electronic patient records.

    Ingimarsson, O., MacCabe, J. H., Haraldsson, M., Jónsdóttir, H. & Sigurdsson, E. 6 Apr 2016 In : Nordic Journal of Psychiatry. PMID: 27049594

    Research output: Contribution to journalArticle

  24. Predictors of treatment resistance in patients with schizophrenia: a population-based cohort study

    Wimberley, T., Støvring, H., Sørensen, H. J., Horsdal, H. T., MacCabe, J. H. & Gasse, C. Apr 2016 In : The Lancet Psychiatry. 3, 4, p. 358–366

    Research output: Contribution to journalArticle

  25. Genetic overlap between type 2 diabetes and depression in Swedish and Danish twin registries

    Kan, C., Pedersen, N. L., Christensen, K., Bornstein, S. R., Licinio, J., MacCabe, J. H., Ismail, K. & Rijsdijk, F. 29 Mar 2016 In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  26. High educational performance is a distinctive feature of bipolar disorder: A study on cognition in bipolar disorder, schizophrenia patients, relatives and controls

    Vreeker, A., Boks, M. P. M., Abramovic, L., Verkooijen, S., Van Bergen, A. H., Hillegers, M. H. J., Spijker, A. T., Hoencamp, E., Regeer, E. J., Riemersma-Van Der Lek, R. F., Stevens, A. W. M. M., Schulte, P. F. J., Vonk, R., Hoekstra, R., Van Beveren, N. J. M., Kupka, R. W., Brouwer, R. M., Bearden, C. E., MacCabe, J. H. & Ophoff, R. A. 1 Mar 2016 In : Psychological Medicine. 46, 4, p. 807-818 12 p.

    Research output: Contribution to journalArticle

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