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  GO-MARK: Investigating Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine

  Jelen, L., Stone, J., Mehta, M. & Young, A.

  MRC Medical Research Council

  1/08/2020 → 31/07/2023

  Project: Research

• Improving Memory in Schizophrenia with PDE4 inibitor Roflumilast – A Phase 0 Proof of Concept Study

  Mehta, M. & Stone, J.

  NIHR National Institute For Health & Care Research

  6/05/2019 → 5/05/2020

  Project: Research

  • Proof-of-Concept 100%
  • Internals 100%
  • Roflumilast 100%
  • Memory 50%

• Gut Feeling: Understanding the Mechanisms Underlying the Antidepressant Properties of Probiotics

  Stone, J., Cleare, A. & Young, A.

  Probiotics International Ltd

  1/10/2018 → 31/03/2022

  Project: Research

• Investigating the role of AMPA receptor blockade in ketamine antidepressant response (IAMBIK)

  Stone, J., Williams, S. & Young, A.

  1/10/2017 → 30/09/2020

  Project: Research

• Neurobiological stratification of patients with first episode psychosis

  Stone, J.

  1/10/2017 → 30/09/2020

  Project: Research

• A pilot study of ketamine tolerance and efficiency for dissociative PTSD

  Reinders, S. & Stone, J.

  1/08/2017 → 31/01/2019

  Project: Research

• Valproate Modulation of Pitch Perception (VAMPP)

  Stone, J., Williams, S. & Young, A.

  1/04/2017 → 31/03/2020

  Project: Research

• Neurobiology of response to clozapine in treatment resistant schizophrenia

  Egerton, A., Barker, G., Howes, O., Maccabe, J., McGuire, P., Stone, J. & Zelaya, F.

  MRC Medical Research Council

  1/02/2017 → 31/08/2018

  Project: Research

• A technological platform for in-vivo validation of functional and metabolic magnetic resonance imaging

  Zelaya, F., Cash, D., Lythgoe, D., Stone, J., Turkheimer, F. & Williams, S.

  9/01/2017 → 31/12/2019

  Project: Research

• Valproate Modulation of Pitch Perception (VAMPP)

  Stone, J., Mill, J., Williams, S. & Young, A.

  1/01/2017 → 31/12/2019

  Project: Research

• The role of glutamate in the neurobiology and treatment of (dissociative) PTSD

  Reinders, S. & Stone, J.

  1/09/2016 → 29/02/2020

  Project: Research

• Dissociation, PTSD, and Ketamine (D-PaK): The role of glutamate in the neurobiology and treatment of (dissociative) PTSD

  Reinders, S., Barker, G., Mehta, M., Stone, J. & Zelaya, F.

  1/01/2016 → 31/12/2018

  Project: Research

• Probiotic supplementation in depressive disorder: a double-blind randomised placebo-controlled feasibility study - PRODEP-F

  Stone, J., Cleare, A. & Young, A.

  1/01/2016 → 31/12/2017

  Project: Research

• Evaluation of the glutamate system as a neurobiological marker for dissociation: A resting-state MRI study of trauma-related and induced dissociation

  Reinders, S., Barker, G., David, A., Dazzan, P., Mehta, M., Stone, J. & Zelaya, F.

  1/07/2015 → 30/06/2018

  Project: Research

• Improving depression treatment: from blood samples to brain insights

  Zunszain, P., Mehta, M., Pariante, C., Price, J., Stone, J., Thuret, S. & Vernon, A.

  1/05/2015 → 30/04/2016

  Project: Research

• Development of a sublingual formulation of ketamine for use in the treatment of depression

  Stone, J., Forbes, B. & Royall, P.

  1/04/2015 → 31/03/2016

  Project: Research

• Reopening of critical period learning with sodium valproate

  Stone, J., Young, A. & academic, A.

  1/04/2015 → 30/09/2016

  Project: Research

• Improving depression treatment: inflammatory and kynurenine pathways as mechanistic targets of ketamine action

  Zunszain, P., Pariante, C., Price, J., Srivastava, D., Stone, J. & Young, A.

  1/04/2015 → 30/09/2016

  Project: Research

• Neuroimaging scopolamine and ketamine antidepressant response

  Stone, J., Mehta, M., Pariante, C., Zelaya, F. & Zunszain, P.

  1/03/2015 → 28/02/2020

  Project: Research

• Synaptic and Neuronal Autoantibodies in Psychosis (SNAP): clinical significance, neuroimaging correlates, infective/immune risk factors

  Pollak, T., David, A., McGuire, P. & Stone, J.

  Wellcome Trust

  4/02/2015 → 9/02/2019

  Project: Research

• Synaptic and Neuronal Autoantibodies in Psychosis (SNAP): clinical significance, neuroimaging correlates and immune/infective risk factors

  Pollak, T., David, A., McGuire, P. & Stone, J.

  4/02/2015 → 4/02/2018

  Project: Research

• GENESIS: Molecular and Imaging Markers of Drug Induced Cerebral Plasticity

  Vernon, A., Srivastava, D., Stone, J. & Turkheimer, F.

  1/02/2015 → 31/01/2016

  Project: Research

• GENESIS: Molecular and imaging markers of drug induced cerebral plasticity

  Vernon, A., Srivastava, D., Stone, J. & Turkheimer, F.

  KHP King's Health Partners

  1/02/2015 → 31/07/2016

  Project: Research

• STRATA - Schizophrenia: Treatment Resistance and Therapeutic Advances

  Maccabe, J., Barker, G., Egerton, A., Howes, O., Kapur, S., Lythgoe, D., McCrone, P., McGuire, P., Murray, R., Pickles, A., Rose, D. & Stone, J.

  MRC Medical Research Council

  1/10/2014 → 31/12/2019

  Project: Research

• STRATA - Schizophrenia: Treatment Resistance and Therapeutic Advances

  Maccabe, J., Barker, G., Egerton, A., Howes, O., Kapur, S., Lythgoe, D., McCrone, P., McGuire, P., Murray, R., Pickles, A., Rose, D. & Stone, J.

  MRC Medical Research Council

  1/10/2014 → 30/09/2019

  Project: Research

• Are the antidepressant effects of ketamine prolonged by lithium treatment?

  Morrison, P., Stone, J. & Young, A.

  1/10/2014 → 30/09/2015

  Project: Research

• Salvinorin A - A pilot investigation of potential antidepressant and anti-addictive properties.

  Stone, J. & Brittain, P.

  1/08/2014 → 31/07/2015

  Project: Research

• NEKTAR: Neuroimaging of Ketamine Treatment and Antidepressant Response

  Stone, J.

  1/03/2014 → 28/02/2019

  Project: Research

• Neurobiology of response to clozapine in treatment resistant schizophrenia

  Egerton, A., Barker, G., Howes, O., Maccabe, J., McGuire, P., Stone, J. & Zelaya, F.

  MRC Medical Research Council

  1/02/2014 → 31/01/2017

  Project: Research

• Neurobiological factors underlying the onset of psychosis.

  McGuire, P., DO NOT USE, P., Howes, O., Kapur, S., Mechelli, A., Stone, J. & Williams, S.

  Wellcome Trust

  1/09/2011 → 28/02/2017

  Project: Research

• Gaba and Glutamate balance in the early phase of psychosis - A Magnetic Resonance Spectroscopy study

  Barker, G., McGuire, P. & Stone, J.

  1/05/2009 → 30/04/2013

  Project: Research

• Gaba and glutamate balance in the early phase of psychosis

  McGuire, P., Stone, J. & Williams, S.

  1/10/2008 → 30/09/2012

  Project: Research

• GABA and glutamate interactions in the development of psychosis

  Stone, J. & Williams, S.

  1/10/2008 → 30/09/2011

  Project: Research

• Is glutamate involved in the development of psychosis? A magnetic Resonance Spectroscopy study

  Stone, J.

  1/07/2008 → 30/06/2010

  Project: Research

• Investigating consciousness with Tetrahydrocannabinol

  Morrison, P. & Stone, J.

  Beckley Foundation

  1/08/2007 → 31/07/2009

  Project: Research

• Investigating the role of brain glutamate in the aetiology of psychosis using magnetic resonance spectroscopy

  McGuire, P., Pilowsky, L., Stone, J. & academic, A.

  MRC Medical Research Council

  1/10/2005 → 30/09/2008

  Project: Research

• The impact of psychosis risk and antipsychotic drug treatment on brain biochemistry as measured by magnetic resonance spectroscopy

  Barker, G., McGuire, P., Murray, R., Pilowsky, L., Stone, J. & academic, A.

  1/06/2005 → 31/05/2008

  Project: Research

• Investigating the role of NMDA receptors in the pathology and treatment of bipolar affective disorder

  Stone, J. & Williams, S.

  1/09/2004 → 31/08/2006

  Project: Research