Research output per year
Research output per year
Personal profile
Research interests
Phase I trials of novel agents in solid tumours; discovery and development of novel immunotherapies; clinical development of new therapies for lung cancer and mesothelioma
Research interests (short)
Clinical trials; Phase 1 trials; Thoracic oncology.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of London
Award Date: 1 Jan 2002
Bachelor of Medicine, University of London
Award Date: 1 Jan 1995
Master of Arts, University of Oxford
Award Date: 1 Jan 1987
External positions
French National Cancer Institute: Integrated Cancer Research Sites - assessment panel
Nov 2023 → …
CHM Cancer Vaccines Expert Working Group
1 May 2023 → …
Scientific Advisory Board of HI-TRON Mainz
1 May 2023 → …
Lead, King's Health Partners Experimental Cancer Medicine Centre
1 Apr 2023 → …
CHM Expert Advisory Group on Oncology & Haematology
1 Apr 2021 → …
MRC Experimental Medicine Panel
1 Nov 2020 → 1 Apr 2023
Protocol Safety Review Board, CANCER RESEARCH UK
1 Jan 2020 → …
Chair, Paediatric ECMC National Network
16 Oct 2017 → 1 Apr 2023
Research Advisory Committee, Sarcoma UK
1 Jan 2015 → 1 Jul 2020
New Agents Committee, CANCER RESEARCH UK
1 Jan 2013 → 1 Jun 2019
British Thoracic Oncology Group Steering Committee
1 Jan 2012 → …
Member
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A phase 1 trial of human telomerase reverse transcriptase (hTERT) vaccination combined with therapeutic strategies to control immune-suppressor mechanisms
Zareian, N., Eremin, O., Pandha, H., Baird, R., Kwatra, V., Funingana, G., Verma, C., Choy, D., Hargreaves, S., Moghimi, P., Shepherd, A., Lobo, D. N., Eremin, J., Farzaneh, F., Kordasti, S. & Spicer, J., 31 Jan 2024, In: Experimental Biology and Medicine. 249, p. 10021 10021.Research output: Contribution to journal › Article › peer-review
Open Access -
A Phase II Study Evaluating PD-L1 Expression in Non-Small Cell Lung Cancer Using [99mTc]NM-01 SPECT/CT, a Technetium-99m Radiolabeled Anti-PD-L1 Single Domain Antibody
Chand, G., Hughes, D., Meszaros, L., Ting, H. H., Moore, A., Johnson, J., Adamson, K., Bailey, D., Spicer, J., Minchom, A. & Cook, G., Jun 2024, In: Journal of Nuclear Medicine. 65 (supplement 2), 241489.Research output: Contribution to journal › Meeting abstract › peer-review
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PD-L1 imaging with [99mTc]NM-01 SPECT/CT predicts early metabolic response to pembrolizumab with or without chemotherapy in advanced non-small cell lung cancer (NSCLC): results from the PECan study.
Hughes, D., Chand, G., Moore, A. E. B., Meszaros, L. K., Johnson, J., Adamson, K., Bailey, D., Tegala, R., Edmonds, S., Ndagire, S., Gennatas, S., Georgiou, A., Ghosh, S., Eleni, K., Josephs, D., McLean, E., Ting, H. H., Spicer, J., Goh, V. & Cook, G., Jun 2024, In: Journal of Nuclear Medicine. 65 (supplement 2), 241338.Research output: Contribution to journal › Meeting abstract › peer-review
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Plasmid DNA ionisable lipid nanoparticles as non-inert carriers and potent immune activators for cancer immunotherapy
Qin, Y., Rouatbi, N., Wang, J. T. W., Baker, R., Spicer, J., Walters, A. A. & Al-Jamal, K. T., May 2024, In: Journal of Controlled Release. 369, p. 251-265 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Predicting programmed death-ligand 1 (PD-L1) expression with fluorine-18 fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) metabolic parameters in resectable non-small cell lung cancer.
Hughes, D., Josephides, E., O'Shea, R., Manickavasagar, T., Horst, C., Hunter, S., Taniere, P., Nonaka, D., Van Hemelrijck, M., Spicer, J., Goh, V., Bille, A., Eleni, K. & Cook, G., 22 Feb 2024, In: European Radiology. 34, 9, p. 5889-5902 14 p.Research output: Contribution to journal › Article › peer-review
Open Access
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KHP Experimental Cancer Medicine Centre
Spicer, J., Gillett, C., Purushotham, A. & Sarker, D.
1/04/2023 → 31/03/2028
Project: Research
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CoL: CRUK City of London Centre renewal (COLMC)
Ng, T., Arnold, J., Blower, P., Ciccarelli, F., Dazzi, F., Farzaneh, F., Grigoriadis, A., Hayday, A., Irshad, S., Kong, A., Kordasti, S., Lawrence, T., Mishto, M., Papa, S., Purushotham, A., Quek, L., Ramsay, A., Reis Ferreira, M., Sarker, D., Sinkus, R., Spicer, J. & Witney, T.
1/04/2022 → 31/03/2027
Project: Research
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Antibody-drug conjugates (ADCs) for the treatment of solid tumours
1/10/2020 → 30/01/2025
Project: Research
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KHP Centre Award - Non-Clinical Training Award
Parker, P., Spicer, J., Ciccarelli, F., Dazzi, F., Farzaneh, F., Hayday, A., Maher, J., Ng, T., Papa, S., Purushotham, A. & Sarker, D.
1/04/2017 → 31/03/2025
Project: Research
Activities
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The Lancet Oncology (Journal)
James Spicer (Peer reviewer)
2014 → …Activity: Publication peer-review and editorial work › Publication peer-review
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European Journal of Cancer (Journal)
James Spicer (Peer reviewer)
2013 → …Activity: Publication peer-review and editorial work › Publication peer-review
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New Agents Committee
James Spicer (Member)
2012 → …Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
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British Journal of Cancer (Journal)
James Spicer (Peer reviewer)
2010 → …Activity: Publication peer-review and editorial work › Publication peer-review
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Journal of the National Cancer Institute (Journal)
James Spicer (Peer reviewer)
2010 → …Activity: Publication peer-review and editorial work › Publication peer-review